 | Casey Kasem als Shaggy (voice) |
 | Grey DeLisle als Daphne (voice) |
 | Mindy Cohn als Velma (voice) |
 | Kathy Kinney als Sheriff Ellen Perkins (voice) |
 | Frank Welker als Fred / Scooby-Doo / Headless Snowman (voice) |
 | Peter Scolari als Professor William Fagen Higginson (voice) |
 | Mark Hamill als Tommy's Father (voice) |
 | Daryl Sabara als Tommy (voice) |
 | Jim Belushi als Asa Buckwald (voice) |
| Scott Jeralds | Director |
| Jonathan Collier | Writer |
| George Doty IV | Writer |
| James Krieg | Writer |
| Ed Scharlach | Writer |
| Joseph Barbera | Executive Producer |
| Pieterjan Kneynsburg | Supervising Producer |
| Sander Schwartz | Executive Producer |
| Marcus Williams | Storyboard Artist |
| Gigi Meroni | Original Music Composer |
| Rich Dickerson | Original Music Composer |
| Chuck Sheetz | Producer |
