 | Kenneth Branagh als William Shakespeare |
 | Judi Dench als Anne Shakespeare |
 | Ian McKellen als Earl of Southampton |
 | Kathryn Wilder als Judith Shakespeare |
 | Lydia Wilson als Susanna Hall |
 | Hadley Fraser als John Hall |
 | Jack Colgrave Hirst als Tom Quiney |
 | John Dagleish als Rafe Smith |
| Sean Foley als John Lane |
 | Gerard Horan als Ben Jonson |
 | Jimmy Yuill als Edward Woolmer |
 | Alex MacQueen als Sir Thomas Lucy |
| Eleanor de Rohan als Margaret Wheeler |
 | Nonso Anozie als Actor |
 | Lolita Chakrabarti als Lena |
| Darryl Clark als Mr. Wheeler |
| Doug Colling als Douglas |
| Clara Duczmal als Elizabeth Hall |
 | Phil Dunster als Harry |
| Freya Durkan als Young Judith Shakespeare |
| Sam Ellis als Hamnet Shakespeare |
| Matt Jessup als Frank |
 | Harry Lister Smith als Jack Cade |
 | Hamish McColl als Judge |
| Sabi Perez als Maria |
 | Michael Rouse als Francis Collins |
 | Penny Ryder als Mrs. Wheeler |
 | Kate Tydman als Lady Thomas Lucy |
| Ian Hearnshaw als Townsman |
| Kenneth Branagh | Director |
| Zac Nicholson | Director of Photography |
| Patrick Doyle | Original Music Composer |
| Úna Ní Dhonghaíle | Editor |
| James Merifield | Production Design |
| Tamar Thomas | Producer |
| Ben Elton | Screenplay |
| Lucy Bevan | Casting |
| Colin Nicolson | Sound Mixer |
| Judy Hofflund | Executive Producer |
| Becca Kovacik | Executive Producer |
| Ted Gagliano | Producer |
| Michael O'Connor | Costume Design |
| Matthew Jenkins | Executive Producer |
| Martin Curry | First Assistant Director |
| Anna Brabbins | Second Assistant Director |
| Laura Berwick | Executive Producer |
| Emily Brockmann | Casting |
| Kenneth Branagh | Producer |
| Andy Nelson | Sound Re-Recording Mixer |
| Deryn Stafford | Production Manager |
| Louise Killin | Line Producer |
| Hannah Spice | Set Decoration |
| David Watkins | Special Effects Supervisor |
| Gavin Rose | Supervising Sound Editor |
| Rob Youngson | Still Photographer |
| Annie Penn | Script Supervisor |
| Larry S. Prinz | Gaffer |
| Dean Marsh | Property Master |
| Charlotte Hutchings | Art Direction |
| Emily Lutyens | Researcher |
| Dillon Bennett | Supervising Sound Editor |
| Tom Sayers | Sound Designer |
| Kellie Waugh | Graphic Designer |
| Vanessa White | Makeup Designer |
| Vanessa White | Hair Designer |
| Ben Brown | First Assistant Camera |
| Bennett Clarke | Second Assistant Camera |
| Harry Bennett-Snewin | Digital Imaging Technician |
| Johannes Lohmann | Camera Trainee |
| Charlotte Hutchings | Standby Art Director |
| Ewa Galak | Art Department Assistant |
| James Gemmill | Scenic Artist |
| Rohan Harris | Scenic Artist |
| Clive Sait | Best Boy Electric |
| Ian Ogden | Key Grip |
| Andy Woodcock | Key Grip |
| Peter Myslowski | Grip |
| Keith Mead | Grip |
| Garth Sewell | Grip |
| Gordon Harmer | Costume Supervisor |
| Anna Kot | Assistant Costume Designer |
| Andrew Joslin | Costume Assistant |
| Martin Chitty | Costume Assistant |
| Jordan Colls | Costume Assistant |
| Carin Hoff | Costume Assistant |
| Manuela Harding | Costume Assistant |
| Hayley Clair Stewart | Costume Assistant |
| John Usher | Costume Assistant |
| Oliver Wilson | Costume Assistant |
| Lesley Altringham | Makeup & Hair |
| Cathy Burczak | Makeup & Hair |
| Linda Wilson | Makeup & Hair |
| Adam James Phillips | Hairdresser |
| Neill Gorton | Prosthetic Designer |
| Isabel Chick | Production Accountant |
| Nick Chaffey | Assistant Accountant |
| Sarah Unwin | Production Coordinator |
| Marina Heumann | Production Secretary |
| Olivia Grant | Casting Associate |
| Cat Gregory | First Assistant Editor |
| Freddie Tyson Brown | Assistant Location Manager |
| Will Hannan | Unit Manager |
| Wojciech Duczmal | Assistant Editor |
| Niv Adiri | Sound Re-Recording Mixer |
| Michael Maroussas | Dialogue Editor |
| Davide Favargiotti | Dialogue Editor |
| Grace Averbuch | Sound Effects Editor |
| Matt Waites | Sound Effects Editor |
| Sebastian Dale | ADR Editor |
| Emmet O'Donnell | Assistant Sound Editor |
| Matthias Schwab | Sound Re-Recording Mixer |
| Phoebe Scholfield | ADR Voice Casting |
| Sophia Hardman | ADR Recordist |
| Carsten Richter | Foley Artist |
| Daniel Weis | Foley Artist |
| Hanse Warns | Foley Mixer |
| Patrick Doyle | Conductor |
| Patrick Doyle | Orchestrator |
| Mark Willsher | Music Editor |
| Colin Nicolson | Production Sound Mixer |
