 | Seth Rogen als Herschel Greenbaum / Ben Greenbaum |
 | Sarah Snook als Sarah Greenbaum |
 | Molly Evensen als Clara |
 | Eliot Glazer als Christian |
 | Kalen Allen als Kevin |
 | Kevin O'Rourke als Dane Brunt |
 | Sean Whalen als Scientist |
 | Geoffrey Cantor als David Greenbaum |
 | Carol Leifer als Susan Greenbaum |
 | Jorma Taccone als Liam |
 | Marsha Stephanie Blake als Inspector Sanders |
 | Alyse Zwick als News Anchor |
 | Dalon Huntington als Border Patrol Agent |
 | Jeremy Michael Grey als Border Patrol Agent |
 | Efka Kvaraciejus als Fish Monger |
 | Darryl Bailey Smith II als Teenage Drone Operator |
| Dino Rende als Teenage Kid |
| Peter Kybart als Old Man |
 | Joanna Adler als Professor Kim Ecklund |
 | Herb Mendelsohn als Rabbi |
 | Norm Golden als Wedding Rabbi |
 | Al Nazemian als Cab Driver |
| Adam Dunhoff als Congregant |
| Mark Diamond als Congregant |
| Leib Cohen als Congregant |
 | Liz Cackowski als Susan O'Malley |
 | Tim Robinson als Prosecuting Attorney |
 | Betsy Sodaro als Defense Attorney |
 | Quinta Brunson als Female Interviewee |
 | Kurt Braunohler als Male Interviewee |
 | Michael Weaver als Judge |
| David Flick als Construction Worker |
| Raymond Neil Hernandez als Officer Kadushin |
 | John Walpole als Seltzer Man |
| Ian Poake als Devon |
 | Charles Rogers als Ellis Island Officer |
| Jess Stark als Female Cashier |
 | Jon Donahue als Local Reporter |
| Amy Marsalis als Reporter |
| Paul Monte Jr. als Second Reporter |
| Julie Mun als Third Reporter |
| Allan Snyder als Moderator |
 | Fabio Polanco als Audience Member |
| Havilah Brewster als Second Audience Member |
| Francis Capone als Manager |
| Alex McAtee als Bartender |
| Dionysius Akeem als Cliff |
 | Nick Arapoglou als Todd (uncredited) |
 | Paul Castro Jr. als Freegan (uncredited) |
 | Alexandre Chen als Chinese Worker (uncredited) |
 | Kristin Cochell als Nika (uncredited) |
 | Chuck Filipov als Schlupsk Man (uncredited) |
 | David Mattey als Ivan (uncredited) |
 | Jeff Daniel Phillips als Actor (uncredited) |
| Adam Ratcliffe als ICE Agent (uncredited) |
| Estes Tarver als ICE Agent (uncredited) |
| Brandon Trost | Director |
| Seth Rogen | Producer |
| Evan Goldberg | Producer |
| James Weaver | Producer |
| Alex McAtee | Executive Producer |
| Ted Gidlow | Executive Producer |
| Lisa Zeno Churgin | Editor |
| Francine Maisler | Casting |
| William Arnold | Production Design |
| Karuna Karmarkar | Set Decoration |
| Brenda Abbandandolo | Costume Design |
| Simon Rich | Screenplay |
| John Guleserian | Director of Photography |
| Nami Melumad | Original Music Composer |
| Michael Babcock | Sound Re-Recording Mixer |
| Chad Djubek | Boom Operator |
| Simon Rich | Short Story |
| Simon Rich | Executive Producer |
| Lynn Kressel | Local Casting |
| Gabe Hilfer | Music Supervisor |
| John Koyama | Stunt Coordinator |
| Hunter Baxley | Stunts |
| Alex Benevent | Stunts |
| Heather Bonomo | Stunts |
| Brian Brown | Stunts |
| Ryan Brown | Stunts |
| Sergei Dmitriev | Stunts |
| Brian Duffy | Stunts |
| Shawn Howell | Stunts |
| Dennis Keiffer | Stunts |
| Krisztian Kery | Stunts |
| Chad Knorr | Stunts |
| Matt Leonard | Stunts |
| Cliff McLaughlin | Stunts |
| Donald Mills | Stunts |
| Paul Nandzik | Stunts |
| Simon Potter | Stunts |
| Matthew Rugetti | Stunts |
| Jason Silvis | Stunts |
| Justin A. Williams | Stunts |
| Ted Gidlow | Unit Production Manager |
| Mark Anthony Little | First Assistant Director |
| Frederic Roth | Second Assistant Director |
| Austin Lapierre | Production Supervisor |
| Gary Kosko | Art Direction |
| Matthew Cavaliero | Property Master |
| Scott Peterson | Script Supervisor |
| Michael Fuchs | "A" Camera Operator |
| Brian Outland | "B" Camera Operator |
| John Ruiz | First Assistant "A" Camera |
| Jason Cianella | Second Assistant "A" Camera |
| Deb Peterson | First Assistant "B" Camera |
| Brian Bresnehan | Second Assistant "B" Camera |
| Chase A. Abrams | Digital Imaging Technician |
| Terra Stuart | Costume Supervisor |
| Tasha Goldthwait | Key Costumer |
| Gina La Monica | Costumer |
| Sierra Mendoza | Costumer |
| James Eidel | Costumer |
| Tori Musial | Costumer |
| Lisa Layman | Makeup Department Head |
| Eve Negley | Key Makeup Artist |
| Doug Fairall | Makeup Artist |
| Vanessa Price | Hair Department Head |
| Candace Orlandi | Key Hair Stylist |
| Robert Sciretta | Chief Lighting Technician |
| Matt Feiler | Assistant Chief Lighting Technician |
| Allan Barch | Lighting Technician |
| Donald Klinefelter | Lighting Technician |
| Jacob Hoyson | Lighting Technician |
| Tom Klabnik | Lighting Technician |
| Sean Murray | Lighting Technician |
| Eliott Acevedo | Lighting Technician |
| Keith Seymour | Key Grip |
| Nick Zinobile | Best Boy Grip |
| Gregory L. Edwards | Dolly Grip |
| Jason Kirker | Dolly Grip |
| David A. Dwyer | Key Rigging Grip |
| Brian Powers | Grip |
| Doug Cronin | Grip |
| John E. Tremba | Grip |
| Taylor Flick | Grip |
| Dan Flick | Grip |
| Jonathan Curotola | Grip |
| Geoff Maxwell | Production Sound Mixer |
| Russell Tyrrell | Special Effects Supervisor |
| Dean Tyrrell | Special Effects Coordinator |
| Shawn Boyachek | Location Manager |
| Jason Calabro | Assistant Location Manager |
| Larry Geyer | Assistant Location Manager |
| James A. Mahathey | Assistant Location Manager |
| Joni Smith | Production Coordinator |
| Gabrielle Gonnella | Production Secretary |
| Lisa Smith-Reed | Assistant Production Coordinator |
| Allison A. Millican | Travel Coordinator |
| Tanoa Parks | Production Accountant |
| Sheruldon P. Herron | First Assistant Accountant |
| Betsy Butterworth | Second Assistant Accountant |
| Grayson Maxwell | Second Assistant Accountant |
| Nathan Matt | Second Assistant Accountant |
| Buster Pile | Construction Coordinator |
| Brad Towell | Graphic Designer |
| Raquel Bouvy | Graphic Designer |
| Joel Cash | Art Department Coordinator |
| Justin Pelissero | Leadman |
| Robin Richesson | Storyboard Artist |
| Adele Plauche | Set Designer |
| Ella Thompson | Assistant Art Director |
| Mike Matesic | Construction Foreman |
| Chip Eccles | Construction Foreman |
| Jolene Dames | Standby Painter |
| C. Scott Baker | Set Designer |
| John Youngblood | Assistant Property Master |
| Jesse Ross | Assistant Property Master |
| Sheryl Main | Unit Publicist |
| Hopper Stone | Still Photographer |
| Jonathan Medeiros | Second Second Assistant Director |
| Molly Rose | Casting Assistant |
| Donna M. Belajac | Local Casting |
| Katie Shenot | Extras Casting |
| Elizabeth Berra | Casting Associate |
| Richard A. Koenig | Transportation Captain |
| Marc Scott | Transportation Coordinator |
| Amanda Bauder | Set Medic |
| Jessica Drake | Dialect Coach |
| Adam Rowland | Visual Effects Supervisor |
| Nancy Kirhoffer | Post Production Supervisor |
| Michael Babcock | Supervising Sound Editor |
| Jeremy Peirson | Sound Effects Editor |
| Jeremy Peirson | Sound Re-Recording Mixer |
| Branden Spencer | Supervising Sound Editor |
| Jeff Sawyer | Sound Effects Editor |
| Laurent Kossayan | Sound Effects Editor |
| Dan Kenyon | Sound Effects Editor |
| Michael Hertlein | Dialogue Editor |
| Shane Hayes | Dialogue Editor |
| Chris Dold | Assistant Editor |
| Jesse Millward | Assistant Editor |
| Michael Costello | First Assistant Editor |
| Sarah Monat | Foley Artist |
| Robin Harlan | Foley Artist |
| Nerses Gezalyan | Foley Mixer |
| Aaron Hasson | ADR Mixer |
| James A. Moore | ADR Mixer |
| Mike Greenberg | ADR Mixer |
| Jason Oliver | ADR Mixer |
| Tran Hong-Thai | Assistant Sound Editor |
| Adam Levin | Assistant Sound Editor |
| Ashley Lambert | ADR Voice Casting |
| Ranjani Brow | ADR Voice Casting |
| Wendy Hoffmann | ADR Voice Casting |
| Paul Apelgren | Music Editor |
| Jeff Kryka | Orchestrator |
| Dennis S. Sands | Scoring Mixer |
| Marshall Bowen | Conductor |
| Andrea Chlebak | Digital Colorist |
| Vanessa Galvez | Digital Intermediate Producer |
| Patrick M. Allen | Digital Intermediate Producer |
| Vikki Chapman | Visual Effects Producer |
| Jason Evans | Visual Effects Supervisor |
| Gregory Oehler | Visual Effects Supervisor |
| Elijah Watson | Visual Effects Coordinator |
| Derek Ledbetter | Visual Effects Supervisor |
| Vincent Robert Rosas | Visual Effects Producer |
| Esme Coleman | Digital Compositor |
| Matt Leonard | Stunt Coordinator |
