 | Cameron Diaz als Elizabeth Halsey |
 | Jason Segel als Russell Gettis |
 | Justin Timberlake als Scott Delacorte |
 | Lucy Punch als Amy Squirrel |
 | John Michael Higgins als Principal Wally Snur |
 | Phyllis Smith als Lynn Davies |
 | Thomas Lennon als Carl Halabi |
 | Molly Shannon als Melody (Garrett's Mom) |
 | Eric Stonestreet als Kirk |
 | Dave Allen als Sandy Pinkus |
 | Matthew J. Evans als Garrett Tiara |
 | Kaitlyn Dever als Sasha Abernathy |
 | Jillian Armenante als Ms. Pavicic |
 | Kathryn Newton als Chase Rubin-Rosse |
| Igal Ben Yair als Arkady |
 | Aja Bair als Devon (Chase's Friend) |
 | Andra Nechita als Gaby |
 | Noah Munck als Tristan |
 | Finneas O'Connell als Spencer |
| Daniel Castro als Rodrigo (Acne Kid) |
 | Adrian Kali Turner als Shawn |
 | Paul Bates als School Superintendent |
| Jeff Judah als Janitor |
 | Nat Faxon als Mark |
 | Stephanie Faracy als Mrs. Pubich |
 | David Paymer als Doctor Vogel |
 | Alanna Ubach als Angela |
| Christine Smith als Danni |
 | Paul Feig als Dad at Carwash |
 | Deirdre Lovejoy als Sasha's Mother |
 | Melvin Mar als Male Teacher (Bathroom) |
 | Rose Abdoo als School Secretary |
 | Jerry Lambert als Morgan's Dad |
 | Jennifer Irwin als Chase's Mom |
| Christopher Rockwell als Chase's Dad |
| David Doty als Armando the Homeless Guy |
 | Rick Overton als Philip |
| Danny Trapp als Cowboy at Palace |
 | Matt Besser als Abraham Lincoln (Tour Guide) |
 | Lee Eisenberg als Blacksmith (Re-Enactor) |
 | Bruno Gunn als Police Officer |
| Jordan Van Vranken als Crying Girl |
| Kadee Noel Brown als Student in Elizabeth's Class (uncredited) |
 | Jennifer Holloway als Sheila (uncredited) |
 | Christina Gabrielle als 8th Grade Student (uncredited) |
| Jake Kasdan | Director |
| Gene Stupnitsky | Screenplay |
| Lee Eisenberg | Screenplay |
| David B. Householter | Producer |
| Gemma La Mana | Still Photographer |
| Jimmy Miller | Producer |
| Tara Timpone | Editor |
| Jefferson Sage | Production Design |
| Michael Andrews | Original Music Composer |
| Alar Kivilo | Director of Photography |
| Debra McGuire | Costume Design |
| Andrew Max Cahn | Art Direction |
| Ronald R. Reiss | Set Decoration |
| Amy McIntyre Britt | Casting |
| Anya Colloff | Casting |
| Lee Eisenberg | Executive Producer |
| Jake Kasdan | Executive Producer |
| Gene Stupnitsky | Executive Producer |
| Georgia Kacandes | Executive Producer |
| Matthew A. Petrosky | Steadicam Operator |
| Jillian Giacomini | Script Supervisor |
| Manish Raval | Music Editor |
| Manish Raval | Music Supervisor |
| Tom Wolfe | Music Supervisor |
| Ronald J. Webb | Music Editor |
| Selena Carrillo | Production Coordinator |
| Chris Baugh | Location Manager |
| Tateum Kohut | Sound Re-Recording Mixer |
| Gregg Landaker | Sound Re-Recording Mixer |
| Anne Couk | First Assistant Sound Editor |
| Brendan Beebe | Boom Operator |
| Robert Grieve | Sound Designer |
| Robert Grieve | Sound Effects Editor |
| Keith Bilderbeck | Sound Effects Editor |
| Paul Berolzheimer | Sound Effects Editor |
| Joel Shryack | Supervising Sound Editor |
| David M. Roberts | Boom Operator |
| Louise DeCordoba | Production Supervisor |
| Georgia Kacandes | Unit Production Manager |
| Ari Jacobs | Art Department Coordinator |
| Peter Robb-King | Makeup Department Head |
| Nina Paskowitz | Hair Department Head |
| Jessie Graff | Stunts |
| G.W. Brown | Dialogue Editor |
| Andrew M. Siegel | Property Master |
| John Pritchett | Sound Mixer |
| Malosi Leonard | Stunt Coordinator |
| Kelli Barksdale | Stunts |
| Joe Bucaro III | Stunts |
| Matt Leonard | Stunts |
| Terry Leonard | Stunts |
| Brian Munce | Stunts |
| Kimberly Shannon Murphy | Stunts |
| K.T. Wiegman | Stunts |
| Thom Williams | Stunts |
| Carey Dietrich | First Assistant Director |
| Bill Purple | Second Assistant Director |
| Carey Dietrich | Associate Producer |
| Melvin Mar | Associate Producer |
| Matt Riley | Associate Producer |
| Monty Rowan | "A" Camera Operator |
| Jimmy E. Jensen | First Assistant "A" Camera |
| Brent Egan | Second Assistant "A" Camera |
| Joseph V. Cicio | "B" Camera Operator |
| Louie DeMarco | First Assistant "B" Camera |
| Tony Muller | Second Assistant "B" Camera |
| Joseph T. Mastrolia | Costume Supervisor |
| Katrina Mastrolia | Key Costumer |
| Maggie Fung | Key Makeup Artist |
| Laurene Alvarado | Makeup Artist |
| Pierce Austin | Hairstylist |
| Soo-Jin Yoon | Hairstylist |
| Richard Thomas | Chief Lighting Technician |
| Joseph Guerino | Assistant Chief Lighting Technician |
| Travis Panarisi | Rigging Gaffer |
| Michael Kenner | Key Grip |
| John Morris | Grip |
| George Santo Pietro | Dolly Grip |
| Michael Herron | Video Assist Operator |
| Gene Rizzardi | Special Effects |
| Michael Betz | Assistant Location Manager |
| Kate Galbraith | Assistant Production Coordinator |
| Tara Guckeen | Production Secretary |
| Jill Rosenblatt | Production Accountant |
| Michelle DeMayo | First Assistant Accountant |
| Rick Roesch | Payroll Accountant |
| Chris Santini | Construction Coordinator |
| Marty Atwell | Construction Foreman |
| Jeffrey A. Brooks | Construction Foreman |
| Carmine Goglia | Standby Painter |
| James E. Tocci | Set Designer |
| Josh Sheppard | Storyboard Artist |
| Bruce Luizzi | Leadman |
| John Herrera McElroy | On Set Dresser |
| Josue Rodriguez | Assistant Property Master |
| Chela Fiorini | Assistant Property Master |
| Amy Cohn | Unit Publicist |
| Audrey Clark Austin | Second Second Assistant Director |
| Steve Windle | Assistant Director Trainee |
| Rhana Alhaid | Producer's Assistant |
| Heinz Healey | Producer's Assistant |
| Ebner Sobalvarro | Producer's Assistant |
| Nathan Kelly | Producer's Assistant |
| Yulia Gershenzon | Costumer |
| Robin Fredriksz | Makeup Artist |
| Lona Vigi | Hairstylist |
| Jesse Lutz | Actor's Assistant |
| Catherine Burt | Actor's Assistant |
| Isaac Kellman Carlen | Production Assistant |
| Katy Galow | Production Assistant |
| Howie E. Kremer | Production Assistant |
| Jason Kumalo | Production Assistant |
| Gavin McGuire | Production Assistant |
| Francine Moss | Production Assistant |
| Joshua Sankar | Production Assistant |
| Chad Witt | Production Assistant |
| Henry Wyler | Production Assistant |
| Juliet Seniff | Casting Associate |
| Nick Mestrundrea | Craft Service |
| Tom Goodrich | Studio Teacher |
| Craig Fehrman | Transportation Captain |
| Melvin Langford, Jr. | Transportation Co-Captain |
| Bethany Orlemann | First Assistant Editor |
| John Dietrick | Assistant Editor |
| Douglas I. Schwartz | Post Production Assistant |
| Shaughnessy Hare | Foley Editor |
| Sarah Monat | Foley Artist |
| Robin Harlan | Foley Artist |
| Randy Singer | Foley Mixer |
| Howard London | ADR Mixer |
| Wendy Hoffman | Loop Group Coordinator |
| Ranjani Brow | Loop Group Coordinator |
| Bruce Botnick | Scoring Mixer |
| Tom Calderaro | Conductor |
| Tom Calderaro | Orchestrator |
| Stephen Kaye | Music Consultant |
| Jonathan Leahy | Music Coordinator |
| Gina Zimmitti | Other |
| Jamie Dixon | Visual Effects Supervisor |
| Michelle Eisenreich | Visual Effects Producer |
| Margo Hunt McKay | Driver |
| Kimberly Shannon Murphy | Stunt Double |
| Jeff Kunkle | Dolly Grip |
