 | Joaquin Phoenix als Beau Wassermann |
 | Patti LuPone als Mona Wassermann |
 | Amy Ryan als Grace |
 | Nathan Lane als Roger |
 | Kylie Rogers als Toni |
 | Denis Ménochet als Jeeves |
 | Parker Posey als Elaine Bray |
 | Zoe Lister-Jones als Young Mona |
 | Armen Nahapetian als Teen Beau |
 | Julia Antonelli als Teen Elaine |
 | Stephen McKinley Henderson als Therapist |
 | Richard Kind als Dr. Cohen |
 | Hayley Squires als Penelope |
 | Julian Richings als Strange Man |
 | Bill Hader als UPS Guy |
 | Alicia Rosario als Liz |
 | James Cvetkovski als Boy Beau |
 | Catherine Bérubé als Hero Beau's Wife |
 | Stephanie Herrera als Martha |
 | Bradley Fisher als Birthday Boy Stab Man |
| Peter Seaborne als Ceiling Man |
 | Michael Esper als Officer Johnson |
 | Manuel Tadros als Cheapo Depot Cashier |
| Karl Roy als Man with Face Tattoos |
| Marc-André Brisebois als Comatose Junkie |
 | Tyrone Benskin als Rattled Businessman |
| Ernest-James Chuipka als Crazy Man |
 | Archie Madekwe als Laughing Man |
| Greg Halpin als Crust Punk (Eye Gouger) |
 | Luis Oliva als Crust Punk (Eyes Gouged) |
| Charles Hardy als Boat Boy |
 | Marie-Michelle Garon als Fraught Mother Looking for Boat Boy |
 | Maev Beaty als Angel / Play Narrator |
 | Patrick Kwok-Choon als Orphan Hero |
 | Michael Gandolfini als Beau’s Son |
 | Théodore Pellerin als Beau’s Son |
 | Mike Taylor als Beau’s Son |
| Luke Alexander James McPhail als Hero Beau's Young Son |
 | Ryan S. Hill als Hero Beau's Young Son |
 | Bentley Hughes als Hero Beau's Young Son |
 | Kwasi Songui als Orphan Ladybug Man |
| Sylvain Landry als Orphan Man w/Mandolin |
 | Tristan D. Lalla als Costume Designer Orphan |
 | Emmanuel Schwartz als Orphan Chorus Member |
 | Cat Lemieux als Orphan Chorus Member |
 | Lily Bird als Samanda |
 | Arthur Holden als Duncan / God on Cloud / Hero Beau’s Wife |
| François Paquette als Yesekov's Body |
 | Alex Bisping als Orphan Production Designer |
| Lucas Gosselin als Orphan Papa Boy |
 | Joe Cobden als News Correspondent (Brian Galloway) |
 | Harry Strandjofski als Superintendent / Catering Manager |
 | Anana Rydvald als Teen Elaine's Mother |
 | Isabelle Brabant als Nurse |
| Tarah Schwartz als News Anchor (BB Stab Man) |
| Barry Morgan als News Anchor (MW Obit) |
 | David Mamet als Rabbi |
| John Walsh als Hearse Driver |
 | Karim Babin als Caterer |
 | Lee Villeneuve als Mona Henchman Who Throws Lawyer |
| Steve Newburn als Monster Puppeteer |
| Kayla Dobilas als Monster Puppeteer |
 | Gord Robertson als Monster Puppeteer |
| Pamela Iveta als Monster Puppeteer |
| Jason Detheridge als Monster Puppeteer |
| Luz Tercero als Mourning Woman |
| Geneviève Marin als Elaine Body Double |
| Julien Fortin als Beau's Twin in Attic |
 | Marc-André Casavant als Dancer (uncredited) |
| Ari Aster | Director |
| Ari Aster | Writer |
| Ari Aster | Producer |
| Lars Knudsen | Producer |
| Pawel Pogorzelski | Director of Photography |
| Fiona Crombie | Production Design |
| Alice Babidge | Costume Design |
| Steve Newburn | Prosthetic Designer |
| Colin Penman | Makeup Department Head |
| Ronald Gilbert | Production Manager |
| Renato De Cotiis | Second Assistant Director |
| Louis Depelteau | Graphic Designer |
| Tyler Gibb | Storyboard Artist |
| Sam Fischer | Color Assistant |
| Adrian Knight | Location Manager |
| Len Blavatnik | Executive Producer |
| Danny Cohen | Executive Producer |
| Elisa Alvares | Executive Producer |
| Timo Argillander | Executive Producer |
| Lucian Johnston | Editor |
| Julie Breton | Casting |
| Jim Carnahan | Casting |
| Kayla Dobilas | Special Effects Makeup Artist |
| Melissa Fafard | Makeup Artist |
| Erik Gosselin | Special Effects Makeup Artist |
| Félix Larivière | Hair Designer |
| Marcelo Padovani | Makeup Department Head |
| Louis Craig | Special Effects Supervisor |
| Claude La Haye | Production Sound Mixer |
| Jonathan Meunier | Sound Assistant |
| Francis Péloquin | Boom Operator |
| David Gaucher | Supervising Art Director |
| Veronique Meunier | Art Direction |
| Jean-Pierre Paquet | Art Direction |
| Charlotte Rouleau | Art Direction |
| Carly Paige Salzman | Makeup Artist |
| Frédéric Amblard | Set Designer |
| Simon Théberge | Set Designer |
| Louis Morin | Visual Effects Supervisor |
| Ryan Terk | VFX Production Coordinator |
| Bobby Krlic | Original Music Composer |
| Marc-André Tratch | Set Designer |
| Nicolas Gosselin | Set Designer |
| Clothilde Caillé-Levesque | Set Designer |
| Stéban Sanfaçon | Art Direction |
| Gillian Nasser | Assistant Art Director |
| Yen-Chao Lin | Assistant Art Director |
| Mario Hébert | Assistant Art Director |
| Philippe Bertrand-Hudon | Makeup Artist |
| Aarif Attarwala | VFX Artist |
| Yuval Levy | Visual Effects Supervisor |
| Keegan McDougall | VFX Artist |
| Jorge Cañada Escorihuela | VFX Supervisor |
| Ann Ruark | Executive Producer |
| Luca Borghese | Co-Producer |
| Vincent Bélisle-Ducharme | Third Assistant Director |
| Florelle Del Burgo | First Assistant Director |
| Dave Flynch | Foley Supervisor |
| Emily Goguen | Sound Recordist |
| Paul Hsu | Supervising Sound Editor |
| Paul Hsu | Sound Re-Recording Mixer |
| Deanna Marano | ADR Recordist |
| Bill Orrico | Dialogue Editor |
| François Pecard | ADR Recordist |
| Jack Rudy | ADR Recordist |
| Brad Tigwell | ADR Recordist |
| David McKeown | Stunt Coordinator |
| Léon Leclerc | Stunts |
| Alex Stines | Stunts |
| Camille Baduraux | Second Assistant Camera |
| Marie-Julie Besse | First Assistant "B" Camera |
| Cristóbal León | Animation |
| Joaquín Cociña | Animation |
| Tyler Campellone | Co-Producer |
| Dylan Twigg | Hairstylist |
| Benjamin Kitchens | Additional Photography |
| Marco Venditto | Gaffer |
| David Dinel | Key Grip |
| Geoffroy St-Hilaire | Steadicam Operator |
| Geoffroy St-Hilaire | "A" Camera Operator |
| Patrick Lima | Dolly Grip |
| Véronique Marchessault | Assistant Costume Designer |
| Myriam Hanahem | Key Costumer |
| Elizabeth Tremblay | Script Supervisor |
| Anne-Lore Vinals | Assistant Set Decoration |
| Marie-Michelle Claveau | Assistant Makeup Artist |
| Hélèna Laliberté | Stunt Driver |
| Alexandre Bleau | Casting Associate |
| Billy Mayo | In Memory Of |
| Alain Clouâtre | In Memory Of |
| Bo Burnham | Thanks |
| David Fincher | Thanks |
| Ruben Östlund | Thanks |
| Paul Thomas Anderson | Thanks |
| Rooney Mara | Thanks |
| Bill Hader | Thanks |
| Lorene Scafaria | Thanks |
| Spike Jonze | Thanks |
| Alain Clouâtre | Set Decoration |
| Joseph Grundfast | VFX Artist |
