 | Virginie Efira als Sister Benedetta Carlini |
 | Charlotte Rampling als Sister Felicita |
 | Daphné Patakia als Bartolomea |
 | Lambert Wilson als Nuncio |
 | Olivier Rabourdin als Alfonso Cecchi |
 | Louise Chevillotte als Sister Christina |
 | Hervé Pierre als Paolo Ricordati |
 | Clotilde Courau als Midea Carlini |
 | David Clavel als Giuliano Carlini |
 | Guilaine Londez als Sister Jacopa |
 | Gaëlle Jeantet als Sister Petra |
 | Justine Bachelet als Sister Juliana |
 | Lauriane Riquet als Sister Roasanna |
 | Eléna Plonka als Young Benedetta |
 | Héloïse Bresc als Christina enfant |
 | Jonathan Couzinié als Jésus-Christ |
 | Vinciane Millereau als Doctor |
 | Jérôme Chappatte als Secretary |
 | Ewan Ribard als Executioner |
 | Nicolas Béguinot als Writer |
 | Satya Dusaugey als Mercenary Dragon |
 | Nicolas Gaspar als Captain of the Mercenaries |
 | Benjamin Penemaria als Captain of Soldiers |
 | Antoine Lelandais als Lieutenant |
 | Frédéric Sauzay als Shepherd |
 | Sophie Breyer als Novice |
 | Célia Kaci als Young Novice |
 | Alexia Chardard als Sister Giulia |
 | Sébastien Chabane als Passerby |
 | Boris Gillot als Merchant |
 | Léa Lopez als Teenager from Pescia #1 |
 | Olga Milshtein als Teenager from Pescia #2 |
 | Pascal Le Corre als Flagellant |
| Raphaël Potier als Plague Victim |
| Philippe Saunier als Resident of Pescia |
 | Fabrice Cals als City Resident |
 | Quentin D'Hainaut als Villager (uncredited) |
| Paul Verhoeven | Director |
| Saïd Ben Saïd | Producer |
| Michel Merkt | Producer |
| Job ter Burg | Editor |
| David Birke | Screenplay |
| Paul Verhoeven | Screenplay |
| Jérôme Seydoux | Producer |
| Jeanne Lapoirie | Director of Photography |
| Anne Dudley | Original Music Composer |
| Katia Wyszkop | Production Design |
| Eric Bourges | Art Direction |
| Pierre-Jean Larroque | Costume Design |
| Jean-Paul Mugel | Sound Mixer |
| Stéphane Batut | Casting |
| Katia Boutin | ADR Supervisor |
| Katia Boutin | Dialogue Editor |
| Antoine Citrinot | Assistant Sound Editor |
| Charles de Ville | Sound Editor |
| Cyril Holtz | Sound Re-Recording Mixer |
| Jules Laurin | Foley Editor |
| Damien Lazzerini | Sound Re-Recording Mixer |
| Damien Luquet | Boom Operator |
| Florian Penot | Assistant Foley Artist |
| Philippe Penot | Foley Artist |
| Alexis Place | Sound Supervisor |
| Margot Saada | ADR Editor |
| Ayelen Camiña | Visual Effects Coordinator |
| Alain Carsoux | Visual Effects Director |
| Marion Frelat | Visual Effects Coordinator |
| Guillaume Le Gouez | Visual Effects Supervisor |
| Emilia Napame | Visual Effects |
| Conchita Airoldi | Executive Producer |
| Kevin Chneiweiss | Associate Producer |
| Fabrice Delville | Co-Producer |
| Arnold Heslenfeld | Co-Producer |
| Teun Hilte | Co-Producer |
| Kateryna Merkt | Associate Producer |
| Laurette Schillings | Co-Producer |
| Job ter Burg | Associate Producer |
| Christophe Toulemonde | Co-Producer |
| Frans van Gestel | Co-Producer |
| Patrick Vandenbosch | Co-Producer |
| Judith C. Brown | Book |
| Thomas Lechevallier | Set Designer |
| Sophie Martel | Set Dresser |
| Thierry Poulet | Assistant Art Director |
| Andrea Grossi | Additional Camera |
| Pascal Bonitzer | Script Consultant |
| Olivier Afonso | Special Effects Makeup Artist |
| Karine Atalla | Makeup Artist |
| Diego Avolio | Makeup Artist |
| Priscilla Baratiny | Makeup Artist |
| Veronica Beffa | Assistant Makeup Artist |
| Véronique Boslé | Hairstylist |
| Amélie Bouilly | Makeup Artist |
| Guillaume Castagné | Special Effects Makeup Artist |
| Sara Cattani | Assistant Makeup Artist |
| Valérie Chapelle | Makeup Artist |
| Antoine Delannoy | Special Effects Makeup Artist |
| Eleonora Dessi | Assistant Makeup Artist |
| Virginie Duranteau | Key Hair Stylist |
| Odile Fourquin | Key Makeup Artist |
| Christine Giugno | Makeup Artist |
| Mathieu Guéraçague | Key Hair Stylist |
| Panos Kondylis | Makeup Artist |
| Frédéric Lainé | Special Effects Makeup Artist |
| Céline Llerena | Special Effects Makeup Artist |
| Alexandra Moulié | Special Effects Makeup Artist |
| Laura Ozier | Key Makeup Artist |
| Francesca Piani | Hairstylist |
| Stefania Piovesan | Assistant Makeup Artist |
| France Rossi | Hairstylist |
| Floris Schuller | Special Effects Makeup Artist |
| Marine Tesson | Makeup Artist |
| Justine Landais | Makeup Trainee |
