 | Johnny Depp als Sam |
 | Mary Stuart Masterson als Juniper 'Joon' Pearl |
 | Aidan Quinn als Benjamin 'Benny' Pearl |
 | Julianne Moore als Ruthie |
 | Oliver Platt als Eric |
 | CCH Pounder als Dr. Garvey |
 | Dan Hedaya als Thomas |
 | Joe Grifasi als Mike |
 | William H. Macy als Randy Burch |
 | Liane Curtis als Claudia |
 | Eileen Ryan als Mrs. Smail |
 | Lynette Walden als Female Customer |
 | Waldo Larson als Waldo |
| Don Hamilton als UPS man |
| Leslie Laursen als Admitting Nurse |
| John Grant Phillips als Policeman |
| Irvin Johnson als Orderly |
| Shane Nilsson als Orderly |
| Faye Killebrew als Video Customer |
 | Ramsin Amirkhas als Video Clerk |
| Amy Alizabeth Sanford als Young Joon |
| Brian Keevy als Young Benny |
| Tony Lincoln als Local |
| Noon Orsatti als Patron |
 | Dan Kamin als Patron |
| Gregory Cook als Guy in the Park (uncredited) |
| Aaron Haedt als Bicyclist (uncredited) |
| Jeremiah S. Chechik | Director |
| Barry Berman | Writer |
| Lesley McNeil | Writer |
| Bill Badalato | Executive Producer |
| Carol Littleton | Editor |
| Donna Roth | Producer |
| Susan Arnold | Producer |
| Lesley McNeil | Associate Producer |
| J. Paul Huntsman | Supervising Sound Editor |
| Lucy Coldsnow-Smith | Foley Editor |
| Jeff Rosen | Foley Editor |
| Pat Tagliaferro | Art Direction |
| Myron Nettinga | Sound Effects Editor |
| Mark Streapy | Second Unit Director of Photography |
| Ralph Osborn | Dialogue Editor |
| Adam Sawelson | Dialogue Editor |
| Suzanne Spangler | First Assistant Editor |
| Pat McCormick | Dialogue Editor |
| Rachel Portman | Original Music Composer |
| Allan Mason | Music Supervisor |
| John Schwartzman | Director of Photography |
| Neil Spisak | Production Design |
| Kimberly Harris | Supervising ADR Editor |
| K.C. Colwell | First Assistant Director |
| Patty York | Key Makeup Artist |
| Martin Lasowitz | Property Master |
| Aggie Guerard Rodgers | Costume Design |
| Mitchell Amundsen | Camera Operator |
| Matthew Sawelson | Dialogue Editor |
| Barbara Munch | Set Decoration |
| Gary C. Bourgeois | Sound Re-Recording Mixer |
| Fríða Aradóttir | Key Hair Stylist |
| Risa Bramon Garcia | Casting |
| Lisa Krueger | Script Supervisor |
| Bruce Birmelin | Still Photographer |
| John Haeny | Supervising Sound Editor |
| Jessica Gallavan | ADR Editor |
| Michael J. Cerone | ADR Recordist |
| James Thornton | Production Sound Mixer |
| David Halbert | Boom Operator |
| Joseph Pisani | Extras Casting |
| Chuck Velasco | Costume Supervisor |
| Heidi Levitt | Casting |
| Noon Orsatti | Stunt Coordinator |
| J.D. Streett | Special Effects Coordinator |
| Paul J. Zydel | ADR Mixer |
| Scott Millan | Sound Re-Recording Mixer |
| Elmo Ponsdomenech | Sound Re-Recording Mixer |
