 | Vin Diesel als Ray Garrison / Bloodshot |
 | Eiza González als KT |
 | Sam Heughan als Jimmy Dalton |
 | Toby Kebbell als Martin Axe |
 | Talulah Riley als Gina Garrison |
 | Lamorne Morris als Wilfred Wigans |
 | Guy Pearce als Dr. Emil Harting |
 | Jóhannes Haukur Jóhannesson als Nick Baris |
 | Alex Hernandez als Tibbs |
 | Siddharth Dhananjay als Eric |
 | Tamer Burjaq als Mombasa Gunman |
 | Clyde Berning als Mombasa Hostage |
 | David Dukas als Merc Driver |
 | Tyrel Meyer als Merc |
 | Alex Anlos als Baris Merc |
 | Maarten Römer als Tech #2 |
 | Charlie Bouguenon als Merc Leader |
 | Nic Rasenti als Guard |
 | Ryan Michael Sin als Ex-RST Employee |
 | Michael Kirch als Ex-RST Employee |
 | Ryan Kruger als Ex-RST Employee |
 | Austin Rose als Ex-RST Employee |
| Gary Naidoo als Ex-RST Employee |
| Hilton Sun als Ex-RST Employee |
| Tsogt Baysgalan als Ex-RST Employee |
| Donovan Goliath als Police Officer #1 |
| Freyja Stern als Gina's Daughter |
 | Keeno Lee Hector als RST Tech |
 | Jeremy Jess Boado als RST Tech |
| Shelani Van Niekerk als RST Tech |
| Jason Goliath als Police Officer #2 |
 | Patrick Kerton als Truck Driver (uncredited) |
| Emmanuel Manzanares als Baris Merc (uncredited) |
 | David Davadoss als Guard |
 | Frans Steyn als Guard |
| Neal H. Moritz | Producer |
| Toby Jaffe | Producer |
| Dinesh Shamdasani | Producer |
| Jason Kothari | Executive Producer |
| Jacques Jouffret | Director of Photography |
| Tom Brown | Production Design |
| Steve Jablonsky | Original Music Composer |
| Jim May | Editor |
| John Papsidera | Casting |
| Tom Brown | Production Design |
| Simon Lamont | Supervising Art Director |
| Michele Barfoot | Set Decoration |
| Kimberly A. Tillman | Costume Design |
| Cheryl Eatock | Line Producer |
| Cheryl Eatock | Executive Producer |
| Eric Heisserer | Screenplay |
| Jeff Wadlow | Screenplay |
| Jeff Wadlow | Story |
| Kevin VanHook | Comic Book |
| Bob Layton | Comic Book |
| Don Perlin | Comic Book |
| Dave Wilson | Director |
| Matthew Antoun | Executive Producer |
| Jeffrey Chan | Executive Producer |
| Vin Diesel | Producer |
| Maurice Fadida | Executive Producer |
| Louis G. Friedman | Executive Producer |
| Jonathan Gray | Executive Producer |
| Rita LeBlanc | Executive Producer |
| Steve Matzkin | Executive Producer |
| Buddy Patrick | Executive Producer |
| Matthew Rhodes | Executive Producer |
| Sarah Schroeder-Matzkin | Executive Producer |
| Mark Strome | Executive Producer |
| Matthew Vaughn | Executive Producer |
| Dione Wood | Co-Producer |
| Yu Dong | Executive Producer |
| Graeme Cowie | Art Direction |
| Moray McGregor | Art Direction |
| Cristiana Serra | Standby Art Director |
| Kelsey Fowler | Additional Photography |
| Diederick Appelcryn | Unit Manager |
| Louis G. Friedman | Unit Production Manager |
| Joseph Gould | Unit Manager |
| James Muringani | Production Supervisor |
| Nadia Paine | Unit Production Manager |
| Kartiki Patil | Production Manager |
| Anne-Marie Roberge | Production Manager |
| Daniel Wee | Production Manager |
| Nadia Brand | Second Assistant Director |
| Steve DeCastro | Second Unit Director |
| Cameron Hadlow | Third Assistant Director |
| Vincent Lascoumes | First Assistant Director |
| Isabel Martens | Second Assistant Director |
| J.J. Perry | Second Unit Director |
| Andre Weavind | First Assistant Director |
| Robert Bentley | Location Scout |
| Dino Denton | Location Manager |
| Ashley Aldworth | Continuity |
| Travis Caverhill | Executive Story Editor |
| Elelwani Netshifhire | Continuity |
| Nua Watford | Assistant Script |
| Hamilton Sterling | Sound Effects Editor |
| Chris Harvey | Visual Effects Supervisor |
| Troy Robinson | Stunt Coordinator |
| Grant Hulley | Stunt Coordinator |
| J.J. Perry | Stunt Coordinator |
| Melissa Moritz | Assistant Costume Designer |
| Gillian Florence | Costume Supervisor |
| Christa Schoeman | Makeup Department Head |
| Natasha du Toit | Makeup Artist |
| Ciara Mulhearn | Makeup Artist |
| Kaylin Mentoor | Makeup Artist |
| Roxy D'Alonzo | Makeup Artist |
| Jaco Snyman | Prosthetic Supervisor |
| Jaco van Heerden | Art Direction |
| Christiana Serra | Art Direction |
| Storm Dysell | Art Direction |
| Brett Hirson | Set Designer |
| Stephanie Clerkin | Set Designer |
| Celene McDowell | Set Designer |
| Catherine Gaum | Set Designer |
| Irma van Heerden | Assistant Set Decoration |
| Paul N.J. Ottosson | Sound Re-Recording Mixer |
| Beau Borders | Sound Re-Recording Mixer |
| Paul N.J. Ottosson | Supervising Sound Editor |
| Paul N.J. Ottosson | Sound Designer |
| Greg ten Bosch | Sound Effects Editor |
| Bob Kellough | Sound Effects Editor |
| Casey Genton | Sound Effects Editor |
| Chuck Michael | Sound Effects Editor |
| Sebastien Francoeur | Visual Effects Supervisor |
| François Dumoulin | Visual Effects Supervisor |
| Arnaud Brisebois | Visual Effects Supervisor |
| Virginie Wintrebert | Visual Effects Producer |
| Philippe Desiront | Visual Effects Supervisor |
| Shaun Brown | Visual Effects Producer |
| Martyn Culpitt | Visual Effects Supervisor |
| Ana Ramos Dominguez | Visual Effects Producer |
| Aaron Eaton | Visual Effects Supervisor |
| Grace Hendley | Visual Effects Producer |
| Jesse Morrow | Visual Effects Supervisor |
| Michael A. Martinez | Digital Compositor |
| Bryan Haines | Digital Compositor |
| Steve Fraser | Visual Effects |
| Jacob Yorke | Digital Compositor |
| Joshua Young | Digital Compositor |
| Christopher Cheng | Digital Compositor |
| Jasper M. Baltzersen | Digital Compositor |
| Tanner Bartlett | Digital Compositor |
| Mario Anger | Digital Compositor |
| Patrick Bacon | VFX Artist |
| Udit Bhardwaj | VFX Artist |
| Don Perlin | Thanks |
| Justin Yu | Fight Choreographer |
| Emmanuel Manzanares | Fight Choreographer |
| Nathan Barris | Stunts |
| Dermot Brogan | Stunts |
| Tony Carbajal | Stunts |
| Ellette Craddock | Stunts |
| Leo Du Plessis | Stunts |
| Lance Elliot | Stunts |
| Warren Germishuys | Stunts |
| Owen Macrae | Stunts |
| Jeremy Marinas | Stunts |
| Minky Ndlovu | Stunts |
| Johann Spilhaus | Stunts |
| Reon Van Der Watt | Stunts |
| Shaun Verth | Stunts |
| Ian Williamson | Stunts |
| Coy Aune | Camera Operator |
| George Loxton | Camera Operator |
| Jimmy E. Jensen | First Assistant Camera |
| Stephen Early | First Assistant Camera |
| Meike Chinnery | First Assistant Camera |
| Andrew Little | First Assistant Camera |
| Nigel Tompkins | Digital Imaging Technician |
| Nicholas McLachlan | Digital Imaging Technician |
| Margaret Muggleston | Second Assistant Camera |
| Isaura Alfonso | Second Assistant Camera |
| Tshepo Nthako | Second Assistant Camera |
| Alexander Ortscheit | Second Assistant Camera |
| Maryke Nel | Key Costumer |
| Tristan Makka | Costumer |
| Alex-Ann Keppie | Costumer |
| Justin Paterson | Chief Lighting Technician |
| Ludwe Balintulo | Rigging Gaffer |
| Dudley Fillies | Rigging Gaffer |
| Phillip Mhlabane | Assistant Chief Lighting Technician |
| Paul Chunkanson | Assistant Chief Lighting Technician |
| Robert Fischer | Key Grip |
| Storm Leonard Williamson | Key Grip |
| Regan Mitchell | Rigging Grip |
| Marius Swart | Grip |
| Lawrence Kutala | Dolly Grip |
| Zahir Karriem | Dolly Grip |
| Nico Louw | Production Sound Mixer |
| Simon Rankin | Boom Operator |
| Maccoh Pingiriasi | Boom Operator |
| Deon Du Preez | Location Manager |
| Wikus van der Merwe | Location Manager |
| Shayne Fuller | Assistant Location Manager |
| Jean Roux | Assistant Location Manager |
| Aqeel Isaacs | Production Coordinator |
| Aphiwe Tshele | Assistant Production Coordinator |
| Viwe Jack-Gcilishe | Production Secretary |
| Billi Bruins | Production Accountant |
| David Krudis | Assistant Accountant |
| Valerie Du Preez | Assistant Accountant |
| Ashley Williams | Payroll Accountant |
| Clive Pollick | Construction Manager |
| Carmen Lötz | Leadman |
| Darren Christian | Concept Artist |
| Jacques Van Rooyen | Art Department Coordinator |
| Clinton Fish | Assistant Property Master |
| Jos Joubert | Assistant Property Master |
| Antoine F. Kock | Assistant Property Master |
| Dezi Rorich | Unit Publicist |
| Graham Bartholomew | Still Photographer |
| Steve M. Ngo | Assistant Editor |
| Esther Sokolow | Assistant Editor |
| Kim Winther | Casting Associate |
| Emily Bohbrink | Casting Assistant |
| J.P. van der Merwe | Extras Casting |
| Lars Cox | Second Unit Director of Photography |
| Andre Weavind | Second Unit First Assistant Director |
| Daniel Saxlid | Supervising ADR Editor |
| Robert Chen | ADR Editor |
| Robert Troy | Dialogue Editor |
| Russell Farmarco | Dialogue Editor |
| Curt Schulkey | Dialogue Editor |
| Ryan Juggler | Assistant Sound Editor |
| Brad Sokol | Assistant Sound Editor |
| Adrian Medhurst | Foley Artist |
| Ryan Squires | Foley Recordist |
| Brendan Croxon | Foley Mixer |
| Howard London | ADR Mixer |
| Paul Pirola | Foley Supervisor |
| Jamie Famularo | Foley Editor |
| Brendan Hill | Foley Editor |
| Darrell Hall | Music Editor |
| Daniel Pinder | Music Editor |
| Nick Glennie-Smith | Conductor |
| Penka Kouneva | Orchestrator |
| Larry Rench | Orchestrator |
| Dan Mintz | Executive Producer |
| Duy Pham | Visual Effects |
