 | Steve Martin als Peter Sanderson |
 | Queen Latifah als Charlene Morton |
 | Eugene Levy als Howie Rottman |
 | Joan Plowright als Mrs. Virginia Arness |
 | Jean Smart als Kate Sanderson |
 | Kimberly J. Brown als Sarah Sanderson |
 | Angus T. Jones als Georgey Sanderson |
 | Missi Pyle als Ashley |
 | Michael Rosenbaum als Todd Gendler |
 | Betty White als Mrs. Kline |
 | Steve Harris als Widow |
 | Jim Haynie als Ed Tobias |
 | Aengus James als Mike |
 | Jernard Burks als Widow's Bodyguard |
| Bronzell Miller als Widow's Bodyguard |
 | Matt Lutz als Aaron |
 | Randy Oglesby als FBI Agent |
 | Jesse Corti als Italian FBI Agent |
 | Smalls als Doorman |
 | Victor Webster als Glen |
 | Teddy Lane Jr. als Big Man |
 | Vincent M. Ward als Big Man |
 | Michael Ensign als Daniel Barnes |
 | Tracey Cherelle Jones als Sofia |
| Josh Waters als College Party Boy |
 | Anne Fletcher als Saleslady |
 | John Prosky als Male Commentator |
 | Alonzo Bodden als Bear |
| Seth Howard als Caddy |
 | Diana Carreno als Hip Hopper |
| Tim Stevenson als Hip Hopper |
 | Eddie Garcia als Hip Hopper |
| Sundy Carter als Flygirl |
 | Anne Bellamy als Hostess |
| Robin Michelle McClamb als Bartender |
 | Walter Addison als Mr. Kline |
 | Gina Morelli als Rosa |
| Seth Altschull als Waiter |
 | Deezer D als Heavy Guy |
 | Kelly Price als Nightclub Singer |
| Candace Jackson als Backup Singer |
| Erika Nuri als Backup Singer |
| Faida Amana Brigham als Down Low Dancer |
| Aminah Abdul-Jillil als Down Low Dancer |
| Barry Lee Youngblood als Down Low Dancer |
 | Cris Judd als Down Low Dancer |
| Oscar Orosco als Down Low Dancer |
| Garland Spencer als Down Low Dancer |
 | Montrose Hagins als Charlene's Neighbor |
| Laura Grady als Hotel Hostess |
 | Erik Betts als House Guest #4 |
 | Christianna Carmine als Club Goer |
| Wahayn Inello Clayton als Club Goer |
| Paul Hopkins als Party Guest |
| Daymond Johnson als Partygoer |
 | Michelle McGinty als Attorney in Photo |
| Lucas Meyers als Valet |
| Bibi Nshimba als Club Goer |
| Lalo Schifrin | Original Music Composer |
| Jason Filardi | Screenplay |
| Ashok Amritraj | Producer |
| Julio Macat | Director of Photography |
| David Hoberman | Producer |
| Queen Latifah | Executive Producer |
| Jane Bartelme | Executive Producer |
| Adam Shankman | Director |
| Gerald B. Greenberg | Editor |
| Aaron Wolf | Production Assistant |
| Victoria Thomas | Casting |
| Michael McQuarn | Music Supervisor |
| Todd Lieberman | Co-Producer |
| Pamela Withers | Costume Design |
| Linda DeScenna | Production Design |
| Daryl Kass | Unit Production Manager |
| Daniel Silverberg | First Assistant Director |
| Cookie Carosella | Associate Producer |
| John Medlen | Stunt Coordinator |
| Robert Jauregui | Stunts |
| Erik Betts | Stunts |
| Jwaundace Candece | Stunts |
| Ron McCord | Stunts |
| Elle Alexander | Stunts |
| Tom Harper | Stunts |
| David Hugghins | Stunts |
| Barbara Bernhardt | Stunts |
| David M. Morizot | Stunts |
| C.C. Taylor | Stunts |
| Mary Fallick | Stunts |
| William Washington | Stunts |
| Ben Jensen | Stunts |
| Chris Daniels | Stunts |
| James Nedza | Art Direction |
| Mitch Sutton | Art Department Coordinator |
| Ric McElvin | Set Decoration |
| Nancy Gilmore | Leadman |
| Virginia Burton | Costume Supervisor |
| Jill Korengold | Set Costumer |
| Tom Macdonald | Costumer |
| Jennifer Dozier | Costumer |
| Lynda Gurasich | Key Hair Stylist |
| Mary Guerrero | Assistant Hairstylist |
| Julie Taylor | Hairstylist |
| Felicity Bowring | Key Makeup Artist |
| Amy Schmiederer | Assistant Makeup Artist |
| Frank Griffin | Makeup Artist |
| Sharron Reynolds-Enriquez | Script Supervisor |
| David MacMillan | Sound Mixer |
| Harrison D. Marsh | Boom Operator |
| Kevin E. Patterson | Utility Sound |
| Ellen Adolph | Production Accountant |
| Gary Levy | First Assistant Accountant |
| Marlene Marks | Payroll Accountant |
| Angie Ryan | Second Assistant Accountant |
| Kim Taylor-Coleman | Casting Associate |
| Nicole Abellara Hallman | Casting Assistant |
| David E. Diano | "A" Camera Operator |
| Rob Morey | First Assistant "A" Camera |
| Craig Kohlhoff | Second Assistant "A" Camera |
| Andy Shuttleworth | "B" Camera Operator |
| David Chameides | Steadicam Operator |
| David Chameides | "B" Camera Operator |
| Andy Shuttleworth | Steadicam Operator |
| David Richert | First Assistant "B" Camera |
| Renee Treyball | Second Assistant "B" Camera |
| Danny Miller | First Assistant Editor |
| David A. Whittaker | Supervising Sound Editor |
| Cliff Latimer | ADR Supervisor |
| James Matheny | Dialogue Editor |
| Donald Flick | Sound Editor |
| Mary Ruth Smith | Sound Editor |
| Shawn Kennelly | Foley Mixer |
| Sean Rowe | Foley Artist |
| Laura Macias | Foley Artist |
| Chris David | Sound Re-Recording Mixer |
| Terry Rodman | Sound Re-Recording Mixer |
| Eric Thompson | ADR Mixer |
| Chris Navarro | ADR Recordist |
| Terri Douglas | ADR Voice Casting |
| Bob E. Krattiger | Gaffer |
| Lonnie S. Gatlin | Best Boy Electric |
| Tim Marshall | Rigging Gaffer |
| Michael Anderson | Key Grip |
| Audie Aragon | Dolly Grip |
| Butch Von Bulow | Dolly Grip |
| Ellen Freund | Property Master |
| David Saltzman | Assistant Property Master |
| Marc A. Hammer | Production Coordinator |
| Lois Walker | Production Coordinator |
| Erin Engman | Assistant Production Coordinator |
| Nancy Deren | Set Designer |
| Rich Romig | Set Designer |
| Dennis DeWaay | Construction Coordinator |
| Steve Fegley | Construction Foreman |
| Molly Allen | Location Manager |
| Kei Rowan-Young | Assistant Location Manager |
| Briana Burke | Assistant Location Manager |
| Shelley Kirkwood | Unit Publicist |
| Paul Murphey | Video Assist Operator |
| Anne Fletcher | Choreographer |
| Griff Ruggles | Transportation Coordinator |
| Ronald Stinton | Transportation Captain |
| Darrell Hall | Music Editor |
| Ira Hearshen | Orchestrator |
| David Orr | Color Timer |
| John Medlen | Second Unit Director |
| Johnny E. Jensen | Second Unit Director of Photography |
| Jennifer Van Shay | Stunts |
| Von L. Roddy | Stunts |
| Larnell Stovall | Stunts |
| Steve Baruch | Stunts |
| Michael Roberts | Stunts |
| Eric J. Van Wagoner | Costumer |
| Shawn Ian Kerkhoff | Assistant Sound Editor |
| Julie Feiner | Dialogue Editor |
| Malcolm Doran II | Second Company Grip |
| James E. Krattiger | Electrician |
| Kenny Schneider | Electrician |
| Glen Magers | Electrician |
| John Fine | Electrician |
| Don Nesmith | Electrician |
| Eugene B. Kerry | Grip |
| Rod Farley | Grip |
| Steve Graves | Grip |
| Bill Slemmons | Grip |
| Christopher Reynolds | Grip |
| Jason Selsor | Rigging Grip |
| James Alden | Rigging Grip |
| William T. Jones | Rigging Grip |
| John Pontrelli | Second Second Assistant Director |
| Kim Meade | Producer's Assistant |
| John McElroy | On Set Dresser |
| Randy Severino | Swing |
| Mark Tuttle | Swing |
| Mark Boucher | Swing |
| Mike Buenfil | Transportation Captain |
| Justin Nelson | Producer's Assistant |
| Teena Deocales | Executive Producer's Assistant |
| LaWanda Black | Executive Producer's Assistant |
| Ilene Waterstone | Actor's Assistant |
| Tracy Mallozzi | Actor's Assistant |
| Andrea Milford | Producer's Assistant |
| Jenny Fumarolo | Production Secretary |
| Naomi Yospe | Production Secretary |
| William Livingston | Construction Foreman |
| Richard Girod Jr. | Standby Painter |
| John Chisholm | Studio Teacher |
| John Shaughnessy | Assistant Location Manager |
| Seth Rappaport | Music Coordinator |
| John E. Rhone | Music Coordinator |
| Gustavo Borner | Scoring Mixer |
| Ruy Folguera | Music Programmer |
| Geoff Levin | Music Programmer |
| Stacy Basil | Animal Wrangler |
| Lisa Bloch-Tobey | Second Unit First Assistant Director |
| Johnny E. Jensen | Director of Photography |
| Peter McKernan | Pilot |
| Peter McKernan Sr. | Pilot |
| Julie Asbury | Production Assistant |
| Solo Douglas | Production Assistant |
| Joe Morganella | Production Assistant |
| Ryan Chavez | Production Assistant |
| Iain Robertson | Production Assistant |
| Jennifer Weiland | Production Assistant |
| Matthew Boeka | Production Assistant |
| Steve Curtiss | Production Assistant |
| Tony Fonseca | Production Assistant |
| Aaron Roberts | Production Assistant |
| Dana Wagner | Production Assistant |
| Sam Emerson | Still Photographer |
| Jean Quay | Set Medic |
| John K. Wright | Craft Service |
| John C.V. Wright | Craft Service |
| Kerry Lyn McKissick | Script Supervisor |
| Mike Strong | Key Rigging Grip |
| Walter Nichols | Gaffer |
| Wayne Marshall | Electrician |
| Adam Glick | Electrician |
| Ralph Stiers | Electrician |
| Gary Mayer | Electrician |
| James Fredburg | Special Effects Supervisor |
| James Lorimer | Special Effects Technician |
| F. Van Way | Special Effects Technician |
| Earl Thielen | Props |
| Jamale Case | Set Medic |
| Angela Amaro | Set Costumer |
| Maggie Hayes | Hairstylist |
| John Zinskey | Craft Service |
| Conte Mark Matal | Second Assistant Director |
| Trey Clinesmith | First Assistant "B" Camera |
