 | Owen Wilson als Lightning McQueen (voice) |
 | Larry the Cable Guy als Mater (voice) |
 | Bonnie Hunt als Sally Carrera (voice) |
 | Paul Newman als Doc Hudson (voice) |
 | Tony Shalhoub als Luigi (voice) |
 | Cheech Marin als Ramone (voice) |
 | Michael Wallis als Sheriff (voice) |
 | George Carlin als Fillmore (voice) |
 | Paul Dooley als Sarge (voice) |
 | Jenifer Lewis als Flo (voice) |
 | Guido Quaroni als Guido (voice) |
 | Richard Petty als The King (voice) |
 | Michael Keaton als Chick Hicks (voice) |
 | Katherine Helmond als Lizzie (voice) |
 | John Ratzenberger als Mack / Hamm Car / Abominable Snow Plow / P.T. Flea Car (voice) |
 | Joe Ranft als Red/Peterbilt (voice) |
 | Jeremy Piven als Harv (voice) |
 | Dale Earnhardt Jr. als Junior (voice) |
 | Mario Andretti als Mario Andretti (voice) |
 | Michael Schumacher als Michael Schumacher Ferrari (voice) |
 | Jay Leno als Jay Limo (voice) |
 | Tom Hanks als Woody Car (voice) |
 | Tim Allen als Buzz Lightyear Car (voice) |
 | Billy Crystal als Mike Car (voice) |
 | John Goodman als Sullivan Truck (voice) |
 | Dave Foley als Flik Car (voice) |
 | Bob Costas als Bob Cutlass (voice) |
 | Darrell Waltrip als Darrell Cartrip (voice) |
 | Richard Kind als Van (voice) |
 | Edie McClurg als Minny (voice) |
 | Humpy Wheeler als Tex (voice) |
 | Tom Magliozzi als Rusty Rust-eze (voice) |
 | Ray Magliozzi als Dusty Rust-eze (voice) |
| Lynda Petty als Mrs. The King (voice) |
 | Andrew Stanton als Fred (voice) |
| Mike Nelson als Not Chuck (voice) |
 | Jan Rabson als T.J. Hummer (voice) |
 | Jonas Rivera als Boost (voice) |
 | Lou Romano als Snotrod (voice) |
| Adrian Ochoa als Wingo (voice) |
| E.J. Holowicki als DJ (voice) |
 | Elissa Knight als Tia (voice) |
 | Lindsey Collins als Mia (voice) |
| Larry Benton als Motorhome Race Fan (voice) |
| Douglas Keever als Motorhome Race Fan (voice) |
 | Sherry Lynn als Additional Voices (voice) |
 | Mickie McGowan als Additional Voices (voice) |
 | Jack Angel als Additional Voices (voice) |
 | Michael Bell als Additional Voices (voice) |
 | Bob Bergen als Additional Voices (voice) |
 | Susan Blu als Additional Voices (voice) |
| Andrea Boerries als Additional Voices (voice) |
| Marco Boerries als Additional Voices (voice) |
 | Rodger Bumpass als Additional Voices (voice) |
| Torbin Xan Bullock als Additional Voices (voice) |
| Richard Cawood als Additional Voices (voice) |
 | Scott Clark als Additional Voices (voice) |
| Kathy Coates als Additional Voices (voice) |
 | John Cygan als Additional Voices (voice) |
 | Jennifer Darling als Additional Voices (voice) |
 | Paul Eiding als Additional Voices (voice) |
 | Bill Farmer als Additional Voices (voice) |
 | Brian Fee als Additional Voices (voice) |
 | Teresa Ganzel als Additional Voices (voice) |
| Craig Good als Additional Voices (voice) |
 | Jess Harnell als Additional Voices (voice) |
| Artie Kempner als Additional Voices (voice) |
| Hooman Khalili als Additional Voices (voice) |
| Sonoko Konishi als Additional Voices (voice) |
| Erik Langley als Additional Voices (voice) |
 | Danny Mann als Additional Voices (voice) |
 | Laraine Newman als Additional Voices (voice) |
 | Teddy Newton als Additional Voices (voice) |
 | Colleen O'Shaughnessey als Additional Voices (voice) |
 | Bob Peterson als Additional Voices (voice) |
 | Steve Purcell als Additional Voices (voice) |
| A.J. Riebli III als Additional Voices (voice) |
 | Dan Scanlon als Additional Voices (voice) |
 | Stephen Schaffer als Additional Voices (voice) |
 | Ken Schretzmann als Additional Voices (voice) |
| Bob Scott als Additional Voices (voice) |
| Matt Staudt als Additional Voices (voice) |
| Jay Ward als Additional Voices (voice) |
 | Jim Ward als Additional Voices (voice) |
 | Colette Whitaker als Additional Voices (voice) |
 | Frank Welker als Frank the combine (voice) (uncredited) |
| John Lasseter | Director |
| Dan Fogelman | Screenplay |
| Darla K. Anderson | Producer |
| Randy Newman | Original Music Composer |
| Ken Schretzmann | Editor |
| William Cone | Production Design |
| Bob Pauley | Production Design |
| Bruno Coon | Music Editor |
| Teresa Eckton | Sound Effects Editor |
| Tom Myers | Supervising Sound Editor |
| David Munier | Special Effects |
| Jessica Giampietro McMackin | Visual Effects Supervisor |
| Joe Ranft | Screenplay |
| John Lasseter | Screenplay |
| Kiel Murray | Screenplay |
| Phil Lorin | Screenplay |
| Jorgen Klubien | Screenplay |
| Kevin Reher | Casting |
| John Lasseter | Original Story |
| Jerome Ranft | Sculptor |
| Hoon H. Kim | Editorial Manager |
| Doug Sweetland | Supervising Animator |
| Laura Leganza Reynolds | Manager of Operations |
| Shannon Mills | Sound Effects Editor |
| Jeremy Lasky | Director of Photography |
| Gary Summers | Sound Re-Recording Mixer |
| Dee Selby | Sound Effects Editor |
| Michael Silvers | Supervising Sound Editor |
| Tom Myers | Sound Designer |
| Thomas Porter | Associate Producer |
| Joe Ranft | Original Story |
| Jorgen Klubien | Original Story |
| Eben Ostby | Supervising Technical Director |
| Scott Clark | Supervising Animator |
| Jonas Rivera | Production Manager |
| Chris Montan | Executive Music Producer |
| Joe Ranft | Script Supervisor |
| Susan E. Levin | Script Supervisor |
| Jean-Claude Kalache | Director of Photography |
| Lee Unkrich | Other |
| Bud Luckey | Character Designer |
| Joe Ranft | Co-Director |
| Joe Ranft | In Memory Of |
| John Zudell | Thanks |
| Ryan Pemberton | Thanks |
| Antonio Ghini | Thanks |
| Connor Funk | Thanks |
| Jay Faye | Thanks |
| Mario Andretti | Thanks |
| Paul Cichocki | Post Production Supervisor |
| Cynthia Slavens | Post Production Supervisor |
| Mark Nielsen | Story Manager |
| Mark Andrews | Additional Storyboarding |
| James S. Baker | Additional Storyboarding |
| Nelson 'Rey' Bohol | Set Designer |
| Anthony Christov | Character Designer |
| Josh Cooley | Additional Storyboarding |
| Brian Fee | Storyboard Artist |
| Dalton Grant | Additional Storyboarding |
| Stephanie Hamilton | Art Department Coordinator |
| Jorgen Klubien | Additional Storyboarding |
| Ellen Moon Lee | Graphic Designer |
| Buck Lewis | Visual Development |
| Albert Lozano | Production Artist |
| Bud Luckey | Concept Artist |
| Bud Luckey | Additional Storyboarding |
| Ted Mathot | Additional Storyboarding |
| Nathaniel McLaughlin | Character Designer |
| Bobby Podesta | Additional Storyboarding |
| Dan Scanlon | Storyboard Artist |
| Gary Schultz | Character Designer |
| Gary Schultz | Set Designer |
| Jay Shuster | Character Designer |
| Jay Ward | Art Department Coordinator |
| Andrea Warren | Art Department Manager |
| Patrick Siemer | Digital Storyboarding |
| Christopher Barrick | Foley Editor |
| Vince Caro | ADR Recordist |
| Sean England | Foley Recordist |
| Ellen Heuer | Foley Artist |
| Larry Hopkins | Production Sound Mixer |
| Doc Kane | ADR Mixer |
| Al Nelson | Assistant Sound Designer |
| Jonathan Null | Foley Editor |
| Juan Peralta | Sound Mix Technician |
| Frank Rinella | Foley Mixer |
| Jurgen Scharpf | Sound Mix Technician |
| Tony Sereno | Sound Mix Technician |
| Steve Slanec | ADR Editor |
| Dennie Thorpe | Foley Artist |
| Jana Vance | Foley Artist |
| Robert Anderson | Layout |
| Carlos Baena | Animation |
| Shane M. Thomas | Art Department Manager |
| Michael Kilgore | Shading |
| Bert Berry | CG Painter |
| Andrew Jimenez | CG Artist |
| Brandon Onstott | CG Artist |
| Jeremy Vickery | CG Artist |
| Neil Blevins | CG Artist |
| Phat Phuong | CG Artist |
| Glenn Kim | CG Painter |
| Jamie Frye | CG Painter |
| Japeth Pieper | CG Painter |
| Laura Phillips | CG Painter |
| Yvonne Herbst | CG Painter |
| Keith Daniel Klohn | VFX Artist |
| Mach Tony Kobayashi | VFX Artist |
| David MacCarthy | VFX Artist |
| David MacCarthy | Visual Effects Technical Director |
| Brad Winemiller | VFX Artist |
| Ferdi Scheepers | VFX Artist |
| Gary Bruins | VFX Artist |
| Jon Reisch | VFX Artist |
| Michael O'Brien | VFX Artist |
| Sandra Ford Karpman | VFX Artist |
| Erdem Taylan | Visual Development |
| Erdem Taylan | VFX Artist |
| Kamal Mistry | VFX Artist |
| Kamal Mistry | Shading |
| Jack Paulus | VFX Artist |
| Jack Paulus | Visual Effects Technical Director |
| Brad Kane | Visual Effects Coordinator |
| Steve May | Visual Effects Supervisor |
| Bob Whitehill | Layout |
| Evan Pontoriero | Modeling |
| Evan Pontoriero | Layout |
| Lisa Kim | Modeling |
| Andrew Pienaar | Lighting Artist |
| Jeremy Birn | Lighting Artist |
| Keith Cormier | Lighting Artist |
| Lloyd Bernberg | Lighting Artist |
| Michael Sparber | Lighting Artist |
| Steven James | Lighting Artist |
| Sungyeon Joh | Lighting Artist |
| Dale Ruffolo | Lighting Artist |
| Dale Ruffolo | Modeling |
| Airton Dittz Jr. | Master Lighting Artist |
| Ken Lao | Master Lighting Artist |
| Tim Best | Master Lighting Artist |
| Ernesto Nemesio | Matte Painter |
| John Lee | Matte Painter |
| Paul Topolos | Matte Painter |
| Lucas Ives | Software Engineer |
| Gordon D.B. Cameron | Software Engineer |
| Christina Garcia Weiland | Set Dressing Artist |
| Mark Leone | Software Engineer |
| Wayne Wooten | Software Engineer |
| Susan Fisher Fong | Software Engineer |
| David Sotnick | Systems Administrators & Support |
| Alison Leaf | Set Dressing Artist |
| Andrew Butts | Shading |
| Andy Whittock | Shading |
| Patrick Guenette | Shading |
| Kiril Vidimce | Software Engineer |
| Holly Lloyd | Visual Effects |
| Joshua Hollander | Visual Effects Producer |
| Kathleen Relyea | Animation Department Coordinator |
| Chris DiGiovanni | Animation Manager |
| Adam Burke | Animation |
| Andrew Gordon | Animation |
| Anthony Ho Wong | Animation |
| Bob Scott | Animation |
| Bobby Beck | Animation |
| Brett Coderre | Animation |
| Brett Pulliam | Animation |
| Brett Schulz | Animation |
| Dan Nguyen | Animation |
| Dave Mullins | Animation |
| David Earl Smith | Animation |
| Don Crum | Animation |
| Ian White | Animation |
| Jason Boose | Animation |
| Jean-Claude Tran | Animation |
| Jon Mead | Animation |
| Karen Kiser | Animation |
| Matt Majers | Animation |
| Matt Nolte | Animation |
| Michael Stocker | Animation |
| Michael Wu | Animation |
| Michal Makarewicz | Animation |
| Rodrigo Blaas | Animation |
| Ron Zorman | Animation |
| Shawn Krause | Animation |
| Marco da Silva | Animation |
| Steve Mason | Animation |
| Tom Gately | Animation |
| Travis Hathaway | Animation |
| Victor Navone | Animation |
| Jaime Landes Roe | Animation |
| Sarah Mercey-Boose | Animation |
| Tasha Wedeen | Animation |
| Bobby Podesta | Animation Director |
| James Ford Murphy | Animation Director |
| Cortney Armitage | Layout |
| Gabriel Schlumberger | Layout |
| Gregg Olsson | Layout |
| Mark Sanford | Layout |
| Sukwon Park | Layout |
| Sungyeon Joh | Layout |
| Suny Behar | Layout |
| Sophie Vincelette | Set Supervisor |
| David Skelly | Story Artist |
| Matthew Luhn | Story Artist |
| Maxwell Brace IV | Story Artist |
| Lee Unkrich | Additional Editor |
| Nicholas C. Smith | Additional Editor |
| Stan Webb | Additional Editor |
| Terry Claborn | Color Timer |
| David Lortsher | Colorist |
| Brice R. Parker | Editorial Coordinator |
| Amera Rizk | Editorial Production Assistant |
| Glenn Kasprzycki | Editorial Services |
| Anna Wolitzky | First Assistant Editor |
| Tessa Swigart | Post Production Assistant |
| Noah Newman | Post Production Coordinator |
| John Hazelton | Projection |
| Kevin Nolting | Second Film Editor |
| Torbin Xan Bullock | Second Film Editor |
| Randy Newman | Conductor |
| Charles Paley | Music Editor |
| David Slusser | Music Editor |
| Lydia Paweski | Music Coordinator |
| Tom MacDougall | Music Supervisor |
| George Doering | Musician |
| Karl Vincent | Musician |
| Kevin Connolly | Musician |
| Frank Marocco | Musician |
| Bruce Morganthaler | Musician |
| Gabe Witcher | Musician |
| James Thatcher | Musician |
| Tommy Morgan | Musician |
| Tom Boyd | Musician |
| Don Williams | Musician |
| Greg Huckins | Musician |
| Frank Wolf | Scoring Mixer |
| Bill Liston | Orchestrator |
| Jonathan Sacks | Orchestrator |
| Chris Schoeneman | Software Engineer |
| Jane Yen | Software Engineer |
| Josh Minor | Software Engineer |
| Malcolm Blanchard | Software Engineer |
| Michael Chann | Software Engineer |
| Paul Strauss | Software Engineer |
| Brendan Donohoe | Software Engineer |
| Tom Lokovic | Software Engineer |
| Lisa S. Young | Software Engineer |
| Jerremy Holland | Software Team Lead |
| Martin Reddy | Software Team Lead |
| Gareth Davis | Software Team Lead |
| Andy Thomas | Systems Administrators & Support |
| Auburn C. 'Aubie' Schmidt | Systems Administrators & Support |
| BoB 'Naked BoB' Morgan | Systems Administrators & Support |
| Chris Lasell | Systems Administrators & Support |
| Gabriel Benveniste | Systems Administrators & Support |
| Ian Westcott | Systems Administrators & Support |
| James G. Dashe | Systems Administrators & Support |
| Jason 'Jayfish' Hull | Systems Administrators & Support |
| Jay Weiland | Systems Administrators & Support |
| Jose Ignacio | Systems Administrators & Support |
| Lars R. Damerow | Systems Administrators & Support |
| Ling Hsu | Systems Administrators & Support |
| Matthew Lindahl | Systems Administrators & Support |
| Peter Ward | Systems Administrators & Support |
| Ross Dickinson | Systems Administrators & Support |
| Terry Lee Moseley | Systems Administrators & Support |
| Will Phan | Systems Administrators & Support |
| Elle Yoko Suzuki | Systems Administrators & Support |
| Nelson Siu | Systems Administrators & Support |
| Craig Foster | Graphic Designer |
| Craig Foster | Title Designer |
| Ellen Moon Lee | Title Designer |
| Gerald E. Hackett III | Security |
| Keith Kops | Security |
| Kristine Javier | Security |
| Marlon Castro | Security |
| Michael Hitson | Security |
| Noah Skinner | Security |
| Paul Chideya | Security |
| Candelaria Lozano | Craft Service |
| Guillermo Segovia | Craft Service |
| Kristen Light | Craft Service |
| Luigi Passalacqua | Craft Service |
| Marie Nilsson | Craft Service |
| Olga Velaszquez | Craft Service |
| Osvaldo Tomatis | Craft Service |
| Erik Forman | Information Systems Manager |
| Bob Roden | Legal Services |
| Dana Basinger | Projection |
| Andy Witkin | Researcher |
| John R. Anderson | Researcher |
| Michael Kass | Researcher |
| Rob Cook | Researcher |
| Tony DeRose | Researcher |
| Mickie McGowan | ADR Coordinator |
| Brad Kane | Special Effects Coordinator |
| Nick Berry | Production Coordinator |
| Erik Langley | Production Assistant |
| Karen Dunn | Project Manager |
| Kay Seirup | Project Manager |
| Renee Adams | Project Manager |
| Tamsen Mitchell | Project Manager |
| Ray Felipe | Script Researcher |
| Adrian Ochoa | Story Coordinator |
| Louis Gonzales | Digital Storyboarding |
| Dustin Cawood | Assistant Sound Editor |
| Jay Kriss | Camera Operator |
| Tom Sanocki | Characters |
| Francisco Figueroa | Craft Service |
| Mark Rinaldi | Dialogue Editor |
| Mickie McGowan | ADR Voice Casting |
| Tia W. Kratter | Shading |
| Tom Myers | Sound Re-Recording Mixer |
| Enrico Casarosa | Story Artist |
