 | Denzel Washington als John Coltrane (voice) |
 | Antonia Andrews als Self - Stepdaughter |
 | Bill Clinton als Self - Politician |
| Michelle Coltrane als Self - Stepdaughter |
| Oran Coltrane als Self - Son |
 | Ravi Coltrane als Self - Son |
 | Common als Self - Musician |
 | John Densmore als Self - Musician |
| Yasuhiro Fujioka als Self - Coltrane's Collector |
| Osaharu Fukushima als Self - Nagasaki Gig Assistant (1966) |
 | Benny Golson als Self - Musician |
| Jimmy Heath als Self - Musician |
| Ashley Kahn als Self - Biographer |
 | Wynton Marsalis als Self - Musician |
| Lewis Porter als Self - Musician |
| Ben Ratliff als Self - Music Critic |
 | Sonny Rollins als Self - Musician |
 | Carlos Santana als Self - Musician |
 | Wayne Shorter als Self - Musician |
 | McCoy Tyner als Self - Musician |
| Kamasi Washington als Self - Musician |
 | Cornel West als Self - Philosopher |
| Reggie Workman als Self - Musician |
| Alice Coltrane als Self - Musician / 2nd Wife (archive footage) |
 | John Coltrane als Self - Musician (archive footage) |
 | Miles Davis als Self - Musician (archive footage) |
 | Martin Luther King Jr. als Self - Civil Rights Activist (archive footage) |
| John Scheinfeld | Director |
| Spencer Proffer | Producer |
| Scott Pascucci | Producer |
| John Scheinfeld | Writer |
| Dave Harding | Producer |
| Stan Taylor | Director of Photography |
| John Beug | Producer |
| Peter S. Lynch II | Editor |
| Peter S. Lynch II | Co-Producer |
| Mark Pinkus | Executive Producer |
| Bruce Resnikoff | Executive Producer |
| Sig Sigworth | Executive Producer |
| John Coltrane | Music |
| Kiku Lani Iwata | Story Manager |
| Kathleen Ermitage | Associate Producer |
| Victoria Thomas | Casting Consultant |
| Dave Harding | First Assistant Camera |
| Aaron Berman | Production Manager |
| Colin Hatton | Production Manager |
| Annette Powlis-Greaux | Production Manager |
| Fred Salkind | Graphic Designer |
| Fred Salkind | Visual Effects |
| Doug Lebow | Graphic Designer |
| Doug Lebow | Visual Effects |
| David Rogers | Graphic Designer |
| David Rogers | Visual Effects |
| Patrick Martin | Photo Retouching |
| Shane Ross | Colorist |
| Marcus Pardo | Sound Re-Recording Mixer |
| Ravi Coltrane | Technical Advisor |
| Paul Bang | Sound |
| Robert Ghiraldini | Sound |
| John Oh | Sound |
| Saul Rouda | Sound |
| Dave Wendlinger | Sound |
