 | Fiona Dourif als Nica Pierce |
 | Brad Dourif als Chucky (voice) |
 | Alex Vincent als Andy Barclay |
 | Jennifer Tilly als Tiffany Valentine |
 | Michael Therriault als Dr. Foley |
 | Adam Hurtig als Michael |
 | Elisabeth Rosen als Madeline |
 | Zak Santiago als Nurse Carlos |
 | Ali Tataryn als Nurse Ashley |
 | Grace Lynn Kung als Claire |
 | Marina Stephenson Kerr als Angela |
 | Allison Dawn Doiron als Rachel |
 | Summer H. Howell als Alice Pierce |
 | Tom Anniko als Chaplain |
 | Darren Wall als Asylum Guard |
| Dan De Jaeger als Orderly #1 |
| Matthew Stefanson als Orderly #2 |
| Dennis Scullard als Asylum Patient (uncredited) |
 | Aidan Ritchie als Asylum Patient (uncredited) |
 | Linden Porco als Body (uncredited) |
 | Lorrie Papadopoulos als Asylum Patient (uncredited) |
| Dustin Kuschnereit als Bartender (uncredited) |
| Paolo Bryant als Orderly (uncredited) |
 | Christine Elise als Kyle |
| Don Mancini | Writer |
| Don Mancini | Director |
| David Kirschner | Producer |
| Ogden Gavanski | Producer |
| Michael Marshall | Director of Photography |
| Randy Bricker | Editor |
| Tony Gardner | Associate Producer |
| Patricia J. Henderson | Costume Design |
| Joseph LoDuca | Original Music Composer |
| Adrien Morot | Makeup Effects |
| Carmen Kotyk | Casting |
| Craig Sandells | Production Design |
| Tanya Mazur | Script Supervisor |
| Gary Oldroyd | Visual Effects Supervisor |
| Michael Chirsky | Picture Car Coordinator |
| Brad Crosbie | Camera Operator |
| Lloyd Brandson | Scenic Artist |
| Marc Reichel | Special Effects Coordinator |
| Shauna Townley | Camera Operator |
| Dries Derycke | Visual Effects Editor |
| Andrew Garrett Lange | Sound Re-Recording Mixer |
| Jonathan Kennedy | Lighting Technician |
| Donna Jenkyns | Art Department Coordinator |
| Laura Souter | Art Department Assistant |
| Laurens Bekaert | Visual Effects Supervisor |
| Callum Graham | Epk Camera Operator |
| Pieter Jongbloed | Assistant Costume Designer |
| Scott Francisco | Music Editor |
| Christel Schoeffaerts | Visual Effects Producer |
| Clint White | Visual Effects Coordinator |
| Chris Van Osselaer | Visual Effects Producer |
| Eric Neufeld | Boom Operator |
| Reil Munro | Dolly Grip |
| Bill Mills | Key Grip |
| Kristy Greig | Assistant Makeup Artist |
| Kim Wright | Assistant Makeup Artist |
| Brenda Magalas | Hairstylist |
| Travis Marszalek | Hairstylist |
| Leanne Neiser | Hairstylist |
| Stacey Mendoza | Key Hair Stylist |
| Alisha Talbot | Makeup Department Head |
| Mathieu Baptista | Special Effects Makeup Artist |
| Doug Morrow | Special Effects Makeup Artist |
| Vague Vartanian | Special Effects Makeup Artist |
| Réjean Labrie | Art Direction |
| C. Summer Holmes | Set Decoration |
| Aaron W.R. Johnston | Assistant Property Master |
| Robert Kestler | Assistant Set Decoration |
| Myles Cook | Carpenter |
| Carey Siddorn | Carpenter |
| Brian Smith | Construction Coordinator |
| Mark Stratton | Property Master |
| Steve Benson | Set Dresser |
| Rachel Kendall | Set Dresser |
| Rob Laurie | Set Dresser |
| Greg Warkentin | Set Dresser |
| Nick Burns | Storyboard Artist |
| Martin Surya | Title Designer |
| Rachael Poklitar | Costumer |
| Barb Myrvold | Seamstress |
| Angela Wells | Set Costumer |
| Michelle Boulet | Truck Costumer |
| Shelly Anthis | Extras Casting |
| Aaron Judlowe | Additional First Assistant Camera |
| Casey Harrison | Assistant Camera |
| James Chrysler | Best Boy Electric |
| Conroy Finnigan | Best Boy Grip |
| Marcus James | Camera Operator |
| Daniel Quesnel | Digital Imaging Technician |
| Steve Madden | Dolly Grip |
| Vince Syposh | Dolly Grip |
| Jack Tunnicliffe | Drone Pilot |
| Trevor Bennett | Drone Cinematographer |
| Blaine Komatich | Electrician |
| Thayer Macinnis | Electrician |
| Aaron Merasty | Electrician |
| Jeremiah Milmine | Electrician |
| Caley Gibson | First Assistant Camera |
| Pascal Boisvert | First Assistant Camera |
| Laurence Mardon | Gaffer |
| Marvin Klein | Generator Operator |
| Wes Reid | Grip |
| Paul Skirzyk | Grip |
| Craig Leatherdale | Grip |
| Devon Unrau | Second Assistant Camera |
| Perry Thompson | Second Assistant Camera |
| Steven K. Johnson | Second Assistant Camera |
| Douglas Mitchell | First Assistant Director |
| Reed Makayev | Second Assistant Director |
| Cody McCullough | Third Assistant Director |
| Travis Dultz | Additional Editor |
| Eric Potter | Assistant Editor |
| Gregg Garvin | Digital Intermediate Colorist |
| Craig Price | Digital Intermediate Editor |
| Carl S.G. Moore | Digital Intermediate Producer |
| Colin Rogers | ADR Mixer |
| Dallas Pomedli | Cableman |
| Tim Chilton | Foley Artist |
| Brandon Sanchez | Foley Artist |
| Colin Rogers | Foley Mixer |
| Leon Johnson | Production Sound Mixer |
| Emilie Corpuz | Sound Mix Technician |
| Patrick Cyccone Jr. | Sound Re-Recording Mixer |
| Verna Mandel | Sound Recordist |
| Tony Gardner | Animatronics Supervisor |
| Davin MacRae | Special Effects Technician |
| Laurent De Greef | Digital Compositor |
| Bert Steyaert | Digital Compositor |
| Daan Tanghe | Digital Compositor |
| Kevin Van Asch | Digital Compositor |
| Jan Van Eetvelt | Digital Compositor |
| Kwinten Debien | Digital Compositor |
| Emiel Strijker | Modeling |
| Olivier Antignac | VFX Artist |
| Roel Herrebrugh | VFX Artist |
| Kumar Gaurav | Visual Effects Producer |
| Pamela B. Green | Creative Director |
| George Goodwin | First Assistant Accountant |
| Tracey Phillips | Payroll Accountant |
| Missy Eustermann | Post Production Accountant |
| Ira Friedlander | Production Accountant |
| Joan Turgeon | Production Accountant |
| Casandra Brescacin | Production Assistant |
| Puneet Chawla | Production Assistant |
| Chris Gabb | Production Assistant |
| Tamara Mauthe | Production Coordinator |
| Sophia Hedlund | Production Executive |
| Liam Karp | Set Production Assistant |
| Karen Tyrell | Unit Publicist |
| Ellen Rutter | Production Manager |
| Sean Skene | Stunt Coordinator |
| Kristen Sawatzky | Stunt Double |
| Brent Poplawski | Stunt Double |
| Brad Crosbie | Steadicam Operator |
| Allen Fraser | Still Photographer |
| Barbara Harris | ADR Voice Casting |
| Mark Simon | Storyboard Artist |
| Don Mancini | Characters |
| Don Mancini | Executive Producer |
| Ellen Rutter | Co-Producer |
| Aaron Graham | Assistant Production Coordinator |
| Echo Andersson | Actor's Assistant |
| Andrew Degryse | Visual Effects Supervisor |
