 | Kenneth Branagh als Hercule Poirot |
 | Tom Bateman als Bouc |
 | Annette Bening als Euphemia Bouc |
 | Russell Brand als Windlesham |
 | Ali Fazal als Andrew Katchadourian |
 | Dawn French als Bowers |
 | Gal Gadot als Linnet Ridgeway |
 | Armie Hammer als Simon Doyle |
 | Rose Leslie als Louise Bourget |
 | Emma Mackey als Jacqueline de Bellefort |
 | Sophie Okonedo als Salome Otterbourne |
 | Jennifer Saunders als Marie Van Schuyler |
 | Letitia Wright als Rosalie Otterbourne |
 | Michael Rouse als Private Laurin |
 | Alaa Safi als Corporal |
 | Orlando Seale als Captain Rens |
 | Charlie Anson als Sergeant Verhaeren |
 | Danny Hughes als Soldier 1 |
| Sam James Page als Soldier 2 |
 | James Schofield als German Soldier 1 |
 | George Jaques als German Soldier 2 |
 | Jonah Rzeskiewicz als German Soldier 3 |
| Eleanor de Rohan als Nurse |
 | Susannah Fielding als Katherine |
 | Adam Garcia als Syd (Photographer) |
 | Rick Warden als Monsieur Blondin |
 | Noel White als Maître 'D Chez Ma Tente |
| Edward Riches als Rhythm Guitar (Band) |
| Dan Ellis als Drums (Band) |
| Megan Affonso als Piano (Band) |
| Gwen Reed als Upright Bass (Band) |
| Jay Phelps als Trumpet (Band) |
| Lois Au als Saxophone (Band) |
 | Rosie Dwyer als Hotel Staff 2 |
 | Niamh Lynch als Female Porter |
 | Nari Blair-Mangat als Hotel Staff 3 |
 | Sid Sagar als Concierge |
| Brenda-Jane Newhouse als Receptionist |
 | Rhiannon Clements als Hotel Administrator |
| Daniel Cook als Hotel Staff 1 |
| Heider Ali als Spice Market Merchant |
 | Hayat Kamille als Snake Handler |
 | Crispin Letts als Officier Besner |
 | Victor Alli als Marc Yves |
| Rachel Feeney als Maxine Cardiff |
| Sarah Eve als Hattie Pyne |
| Aron Julius als Will Goodwin |
| Francis Lovehall als Allerton McNaught |
 | Stacy Abalogun als Elinor Glyn |
| Naveed Khan als Captain Mahmoud |
| Katie Smale als Berel Genevese |
| Kemi Awoderu als Alessande Johar |
| Kenneth Branagh | Director |
| Agatha Christie | Novel |
| Haris Zambarloukos | Director of Photography |
| Patrick Doyle | Original Music Composer |
| Jim Clay | Production Design |
| Kenneth Branagh | Producer |
| Judy Hofflund | Producer |
| Ridley Scott | Producer |
| Kevin J. Walsh | Producer |
| Matthew Jenkins | Executive Producer |
| James Prichard | Executive Producer |
| Mathew Prichard | Executive Producer |
| Michael Green | Screenplay |
| Jamie Hearing | VFX Artist |
| Úna Ní Dhonghaíle | Editor |
| Steven Lawrence | Art Direction |
| Katrina Mackay | Art Direction |
| Mike Stallion | Art Direction |
| Stephen Swain | Art Direction |
| Dominic Masters | Supervising Art Director |
| Abi Groves | Set Decoration |
| Shreya Patel | Makeup Supervisor |
| Alice Biddle | Assistant Art Director |
| Rupert Hancock | Set Dresser |
| Richard Hardy | Assistant Art Director |
| Celene McDowell | Assistant Art Director |
| Mike Dowson | Sound Re-Recording Mixer |
| Gilbert Lake | Sound Re-Recording Mixer |
| Jed Loughran | Sound Effects Editor |
| David Mackie | Sound Effects Editor |
| James Mather | Supervising Sound Editor |
| Kevin Penney | Sound Effects Editor |
| Rowan Watson | Sound Effects Editor |
| Scott Balkcom | Visual Effects |
| Jon Bowen | Visual Effects Supervisor |
| Annie Cliche | Visual Effects Producer |
| Jacinthe Côté | Visual Effects Producer |
| Claudia Dehmel | Visual Effects Producer |
| Daniel Hazeltine | VFX Artist |
| Sunil Kamath | Visual Effects Supervisor |
| Ketan Karekar | Visual Effects Producer |
| Owen McGonigle | VFX Artist |
| David Moreno Hernandez | Visual Effects Supervisor |
| George Murphy | Visual Effects Supervisor |
| Mathieu Raynault | Visual Effects Supervisor |
| Maïté Chemin | Set Costumer |
| Christof Roche-Gordon | Costume Supervisor |
| Alice Speak | Set Costumer |
| Lucy Bevan | Casting |
| Paco Delgado | Costume Design |
| Mark Gordon | Executive Producer |
| Simon Kinberg | Executive Producer |
| Leo Woodruff | Stunts |
| Reg Wayment | Stunts |
| Elmo Walker | Stunts |
| Chris Waite | Stunt Driver |
| Arran Topham | Stunt Double |
| Peter Syckelmoore | Stunts |
| Laura Swift | Stunt Double |
| Shane Steyn | Stunt Driver |
| Sam Stefan | Stunt Double |
| Jamie Stanley | Stunts |
| Jon Slayer | Stunts |
| Caroline Simonnet | Utility Stunts |
| Christina Petrou | Stunts |
| James O'Donnell | Stunt Coordinator |
| Kye Mckee | Stunts |
| Freddie Mason | Stunts |
| Nora Henderson | Stunts |
| Renars Latkovskis | Stunts |
| Jack Jagodka | Stunt Double |
| Luke Gomes | Stunt Double |
| James Embree | Stunts |
| Josh Dyer | Stunts |
| Dom Dumaresq | Stunt Double |
| Tim Davies | Stunts |
| Christoph Cordell | Stunts |
| Liam Coote | Stunt Double |
| Joel Conlan | Stunts |
| Neil Chapelhow | Stunts |
| Dacio Caballero | Utility Stunts |
| Emma Britton | Stunts |
| Tom Boney | Stunts |
| Matt Crook | Stunts |
| Lucy Allen | Stunts |
| Colin Nicolson | Sound Mixer |
