 | Michael Chiklis als Slade Wilson / Deathstroke (voice) |
 | Sasha Alexander als Adeline 'Addie' Kane Wilson (voice) |
 | Chris Jai Alex als Jackal (voice) |
 | Faye Mata als H.I.V.E. Queen / Jade (voice) |
 | Griffin Puatu als Joseph Wilson / Jericho (voice) |
 | Asher Bishop als Young Joseph Wilson (voice) |
 | Imari Williams als President Nicholas / H.I.V.E. Pilot (voice) |
 | Colin Salmon als William Wintergreen (voice) |
 | Delbert Hunt als Bronze Tiger (voice) |
 | Panta Mosleh als Lady Shiva / Nurse (voice) |
 | Noshir Dalal als Kapoor / Doctor 2 (voice) |
 | Castulo Guerra als General Suarez / Doctor (voice) |
 | Minae Noji als Newscaster / Secretary of State (voice) |
| Sung Jin Ahn | Director |
| J. M. DeMatteis | Screenplay |
| Kevin Riepl | Music |
| Robbee Jones | Production Manager |
| Tristan Warren | Sound Mixer |
| James Lucero | Sound Supervisor |
| Bret Johns | Sound Designer |
| Michael Britt | Sound Editor |
| Sung Jin Ahn | Storyboard Artist |
| Matthew Bordenave | Storyboard Artist |
| JJ Conway | Storyboard Artist |
| Adam Ford | Storyboard Artist |
| Emily Hu | Storyboard Artist |
| Sinae Jung | Storyboard Artist |
| Brandon McKinney | Storyboard Artist |
| Douglas Einar Olsen | Storyboard Artist |
| Kevin Reed | Storyboard Artist |
| Jam Respicio | Storyboard Artist |
| Fill Marc Sagadraca | Storyboard Artist |
| Sung Shin | Storyboard Artist |
| Erin Won | Storyboard Designer |
| Jing Ouyang | Character Designer |
| Justin Schultz | Animation Coordinator |
| Greg Emerson | Post Production Supervisor |
| Brian E.S. Jones | Executive In Charge Of Production |
| Tracy Nicoletti | Production Assistant |
| Sam Register | Executive Producer |
| Greg Berlanti | Executive Producer |
| Sarah Schechter | Executive Producer |
| Marv Wolfman | Characters |
| George Pérez | Characters |
| Todd Raleigh | Editor |
| Colin A.B.V. Lewis | Line Producer |
| Matthew Girardi | Supervising Technical Director |
| Ben Kalina | Production Supervisor |
| Chris Prynoski | Production Supervisor |
| Shannon Prynoski | Production Supervisor |
| Kyle O'Connor | Sound Editor |
