 | Matt Lanter als Will |
 | Vanessa Lachey als Amy |
 | Gary 'G. Thang' Johnson als Calvin |
 | Nicole Parker als Enchanted Princess / Amy Winehouse Look-A-Like / Jessica Simpson Look-A-Like |
 | Crista Flanagan als Juney / Hannah Montana |
 | Kim Kardashian als Lisa |
 | Ike Barinholtz als Wolf / Javier Bardem Look-A-Like / Police Officer / Hellboy / Batman / Beowulf / Prince Caspian |
 | Carmen Electra als Beautiful Assassin |
 | Tony Cox als Indiana Jones |
 | Tad Hilgenbrink als Prince |
 | Nick Steele als Underwear Model |
 | John Di Domenico als Dr. Phil Look-A-Like / Love Guru |
 | Jason Boegh als Male Carrie |
 | Valerie Wildman als Samantha |
 | Abe Spigner als Flava-Flav Look-A-Like |
 | Noah Harpster als Jonah |
 | Austin Michael Scott als McLover |
 | Devin Crittenden als Michael Cera Look-A-Like |
| Dana Seltzer als Head On Voice |
 | Robin Atkin Downes als Emergency Broadcaster (voice) |
 | Michelle Lang als Hot Girl |
| Jonas Neal als Justin Timberlake Look-A-Like |
| Walter Harris als Hancock |
 | Jacob Tolano als Bruce Banner |
| Hal Olofsson | Executive Producer |
| Peter Safran | Producer |
| Christopher Lennertz | Original Music Composer |
| Jason Friedberg | Producer |
| Aaron Seltzer | Producer |
| Peck Prior | Editor |
| Shawn Maurer | Director of Photography |
| Aaron Seltzer | Director |
| Jason Friedberg | Director |
| Jason Friedberg | Writer |
| Aaron Seltzer | Writer |
| Jerry P. Jacobs | Co-Producer |
| Kenny Yates | Associate Producer |
| William A. Elliott | Production Design |
| Frank Helmer | Costume Design |
| Dave Jordan | Music Supervisor |
| Jojo Villanueva | Music Supervisor |
| Amanda Koblin | Casting |
| Jerry P. Jacobs | Unit Production Manager |
| Hal Olofsson | First Assistant Director |
| Jennifer Booth | Production Supervisor |
| Keith Adams | Stunt Coordinator |
| Henry Kingi Jr. | Stunts |
| Terra Abroms | Post Production Supervisor |
| Daniel A. Lomino | Art Direction |
| Steven M. Saylor | Set Designer |
| Teresa Visinare | Set Decoration |
| Robert Lucas | Leadman |
| James Allen Bradley | Set Dresser |
| Ed Burcham | Set Dresser |
| Phillip Joffrion | Set Dresser |
| Jon Baronn Farmer | Still Photographer |
| William D. Barber | "A" Camera Operator |
| Jeffrey N. Civa | First Assistant "A" Camera |
| Brandon Dauzat | Second Assistant "A" Camera |
| Greg Williams | "B" Camera Operator |
| Brouke Franklin | First Assistant "B" Camera |
| Danny Horne | Second Assistant "B" Camera |
| Alfredo Rosado | First Assistant "C" Camera |
| Darby Newman | Second Assistant "C" Camera |
| Dustin W. Logan | Video Assist Operator |
| Larry Long | Sound Mixer |
| Misty Conn | Boom Operator |
| Don Miloyevich | Property Master |
| Andrew Wert | Assistant Property Master |
| Jody Blose | Script Supervisor |
| Michael T. Ryan | Supervising Music Editor |
| Anna MacKenzie | Supervising Sound Editor |
| Adam Jenkins | Sound Re-Recording Mixer |
| Orest Sushko | Sound Re-Recording Mixer |
| Jeremy Launais | Gaffer |
| Darwin Montana Browne | Key Grip |
| Mary Matthews | Costume Supervisor |
| Paul Corricelli | Key Costumer |
| Douglas Noe | Makeup Department Head |
| Leslie Devlin | Key Makeup Artist |
| Jack Lazzaro | Makeup Artist |
| Matthew W. Mungle | Makeup Effects Designer |
| Richard Redlefsen | Special Effects Makeup Artist |
| Gary J. Perticone | Hair Department Head |
| Roxanne Ferguson | Key Hair Stylist |
| John Mattingly | Second Second Assistant Director |
| Daniel Coe | Construction Coordinator |
| Jeff Dash | Production Accountant |
| Jim Swidarski | Payroll Accountant |
| Susan Steeno | Unit Publicist |
| Greg Faucett | Transportation Coordinator |
| Mike Sowa | Digital Intermediate Colorist |
| Ryan Helsley | Digital Intermediate Producer |
| Donnie Creighton | Digital Intermediate Producer |
| Valance Eisleben | Digital Intermediate Editor |
| Cory Milano | Music Editor |
| Rebekah Johnson | Music Coordinator |
| Dino DiMuro | Sound Effects Editor |
| Glynna Grimala | Sound Effects Editor |
| Harry Cohen | Sound Effects Editor |
| Peter Staubli | Sound Effects Editor |
| Karen Vassar Triest | Sound Effects Editor |
| Dan Hegeman | Sound Effects Editor |
| Zack Davis | Dialogue Editor |
| Laura Harris Atkinson | Dialogue Editor |
| Frederick H. Stahly | Dialogue Editor |
| Robert Deschaine | ADR Mixer |
| Tami Treadwell | ADR Mixer |
| Martin Schloemer | ADR Recordist |
| Zane D. Bruce | Foley Artist |
| Joseph T. Sabella | Foley Artist |
| Jeff Gunn | Foley Artist |
| James B. Howe | Foley Mixer |
| Don Givens | Foley Mixer |
| Caitlin McKenna | ADR Voice Casting |
| Jeremy Hunt | Visual Effects Supervisor |
| Harry Muller | Color Timer |
| James Wright | Dolby Consultant |
| Helena Barrett | Stunts |
| Deven MacNair | Stunts |
| Jared S. Eddo | Stunts |
| Kym Stys | Stunt Double |
