 | Adam Devine als Raphael (voice) |
 | Eric Bauza als Donatello (voice) |
 | Anders Holm als Leonardo (voice) |
 | Blake Anderson als Michelangelo (voice) |
 | Matthew Yang King als Splinter / Shredder (voice) |
| Jhonen Vasquez | Writer |
| Sung Jin Ahn | Director |
| Andrew Huebner | Producer |
| Laura Sreebny | Production Manager |
| Joshua Hoskison | Production Coordinator |
| Larisa Perelman | Production Coordinator |
| Gene Vassilaros | Casting Director |
| Shiondre Austin | Casting |
| Morgann Franson | Casting Coordinator |
| Courtney Moon | Casting Assistant |
| Anna Adams | Dialogue Editor |
| Justin Brinsfield | Sound Director |
| Yi Song | Animation |
| Parker Simmons | Animation |
| Johnny Koester | Animation |
| Brian Pak | Animation |
| Hanho Heung Up | Animation |
| Jason Lazarus | Original Music Composer |
| Konrad Pinon | Sound Re-Recording Mixer |
| Peter Laird | Characters |
| Kevin Eastman | Characters |
