 | Gerard Butler als Dracula |
 | Christopher Plummer als Matthew Van Helsing |
 | Jonny Lee Miller als Simon Sheppard |
 | Justine Waddell als Mary Heller |
 | Vitamin C als Lucy Westerman |
 | Jennifer Esposito als Solina |
 | Omar Epps als Marcus |
 | Sean Patrick Thomas als Trick |
 | Danny Masterson als Nightshade |
 | Lochlyn Munro als Eddie |
 | Tig Fong als Dax |
 | Tony Munch als Charlie |
 | Jeri Ryan als Valerie Sharpe |
 | Shane West als JT |
 | Nathan Fillion als Father David |
 | Tom Kane als Anchor Man |
 | Jonathan Whittaker als Gautreaux |
 | Robert Verlaque als Dr. Seward |
 | Randy Butcher als Stakeman #1 |
 | Bill Davidson als Stakeman #2 |
| Peter Cox als Stakeman #3 |
| Chris Lamon als Stakeman #4 |
| Herb Reischl Jr. als Stakeman #5 |
 | Duncan McLeod als Stakeman #6 |
| Wayne Downer als Desk Guard |
 | Robert Racki als Door Guard |
 | William Prael als Parade Cop |
| Kaaron Briscoe als Teen Co-Worker |
| Scarlett Huntley als Blood Doll |
| Harold Short als Black Angel of Death |
| David J. Francis als Jesus |
| Shimmy Silverman als Barker |
| Christopher Boyes | Sound Re-Recording Mixer |
| Bill Abbott | Music Editor |
| Bob Weinstein | Executive Producer |
| Harvey Weinstein | Executive Producer |
| Peter Pau Tak-Hai | Director of Photography |
| Dan Hubbard | Casting |
| Marco Beltrami | Original Music Composer |
| Marco Beltrami | Music Supervisor |
| Sarah Halley Finn | Casting |
| Wes Craven | Executive Producer |
| Wes Craven | Presenter |
| Steve Boeddeker | Sound Designer |
| Carol Spier | Production Design |
| Brian Jagersky | Stunts |
| David M. Dunlap | Additional Photography |
| Denise Cronenberg | Costume Design |
| Elinor Rose Galbraith | Art Direction |
| Laeta Kalogridis | Thanks |
| Joel Soisson | Screenplay |
| Joel Soisson | Producer |
| Joel Soisson | Story |
| Randi Hiller | Casting |
| Marianne Maddalena | Executive Producer |
| Patrick Lussier | Director |
| Patrick Lussier | Story |
| Peter Devaney Flanagan | Editor |
| Erik Henry | Visual Effects Supervisor |
| W.K. Border | Producer |
| Brian Campbell | Unit Production Manager |
| Andrew Rona | Executive Producer |
| Eileen Weisinger | Stunts |
| Gary J. Tunnicliffe | Special Effects Makeup Artist |
| Ron Schmidt | Co-Producer |
| Eric Bryson | Stunts |
| Ken Quinn | Stunt Double |
| Claire Jane Vranian | Special Effects Makeup Artist |
| Vasile Albineț | Stunts |
| Dicu Aurel | Stunts |
| Gary Rizzo | Sound Re-Recording Mixer |
| Koichi Sakamoto | Stunt Coordinator |
| Kurt Bryant | Stunts |
| Jim Kaufman | Second Unit Director |
| Jeff Galpin | Stunts |
| Stacy Kelly | Makeup Artist |
| Peter Nicolakakos | Set Decoration |
| David Ebner | Visual Effects Supervisor |
| Donna Chance | Set Costumer |
| Wayne Downer | Stunts |
| Marese Langan | Makeup Artist |
| Paul Mitchnick | Second Unit Director of Photography |
| Linda Gardar | Costume Supervisor |
| Frank E. Eulner | Supervising Sound Editor |
| Gwendolyn Yates Whittle | ADR Supervisor |
| Branko Racki | Stunts |
| Chris Howard | Gaffer |
| Chris Scarabosio | Sound Effects Editor |
| Mary Frances Eglin | Art Department Coordinator |
| Donna Spahn | Makeup Department Head |
| Daniele Colajacomo | Visual Effects Supervisor |
| Michael Madden | Set Designer |
| Gordon White | Set Designer |
| Brenda Gilles | Assistant Costume Designer |
| Dawn Rivard | Art Department Coordinator |
| Ion Carangea | Stunts |
| Mary-Lou Green-Benvenuti | Key Hair Stylist |
| Brad Kuehn | Visual Effects Supervisor |
| Howard Rothschild | First Assistant Director |
| Daniel K. Arredondo | Co-Producer |
| Randy Butcher | Stunts |
| Ed Gerrard | Music Supervisor |
| Gray Marshall | Visual Effects Supervisor |
| Courtney Gross | Casting Associate |
| Uel Hormann | Visual Effects Supervisor |
| Sean Sansom | Special Effects Makeup Artist |
| Taryn Ash | Stunts |
| Douglas Ganton | Production Sound Mixer |
| Reynald Trudel | Production Sound Mixer |
| Tony Steinberg | Associate Producer |
| Tony Steinberg | First Assistant Director |
| Kevin Hourigan | Third Assistant Director |
| Dave Van Zeyl | Stunts |
| Daryl Patchett | Stunts |
| Marla Casey | Stunts |
| Steven Lawrence | Special Effects Makeup Artist |
| Leigh Bianco | Stunts |
| Jennifer Vey | Stunts |
| Mic Jones | Stunts |
| Erin Jarvis | Stunts |
| Don Stockford | Stunt Double |
| Henry Korhonen | Stunt Double |
| Bryan J. Thomas | Stunts |
| G. Michael Currie | Second Assistant Director |
| Peter Cox | Stunts |
| Erron Gee | Stunts |
| Wendi Lynn Avignone | Makeup Artist |
| Chad Keens-Douglas | Stunts |
| Ted Ross | Special Effects Coordinator |
