 | Lily Tomlin als Edith Ann (voice) |
 | Thom Sharp als Dad (voice) |
 | Pamela Adlon als Irene (voice) |
 | Amy Ziff als Mom / Ida Milfred (voice) |
| Kellen Hathaway als Hub Matthews (voice) |
 | Carolyn Lawrence als Becca / Pam Glam (voice) |
 | Jarrett Lennon als Torky Alden (voice) |
| Sherry Lynn als Nita / Tooie Larson (voice) |
| Adam Ryen als Thomas Valdez (voice) |
 | Kath Soucie als Birdie / Vic (voice) |
| Tamara Varga | Director |
| Gábor Csupó | Executive Producer |
| Sherry Gunther | Producer |
| Arlene Klasky | Executive Producer |
| Lily Tomlin | Executive Producer |
| Jane Wagner | Executive Producer |
| Rusty Andrews | Music |
| Mark Mothersbaugh | Music |
| Bill Wilner | Editor |
| David L. Allen | Background Designer |
| Peter S. Carlstedt | Supervising Sound Editor |
| Andy Jolliff | Digital Compositor |
| Rick Arbuckle | Dialogue Editor |
| Carol Stoddard | Still Photographer |
| Denis M. Hannigan | Additional Music |
| Jane Wagner | Writer |
