 | Kenneth Branagh als Miguel (voice) |
 | Kevin Kline als Tulio (voice) |
 | Rosie Perez als Chel (voice) |
 | Armand Assante als Tzekel-Kan (voice) |
 | Edward James Olmos als Chief (voice) |
 | Jim Cummings als Cortes (voice) |
 | Frank Welker als Altivo (voice) |
 | Tobin Bell als Zaragoza (voice) |
 | Elton John als Narrator (voice) |
 | Duncan Marjoribanks als Acolyte (voice) |
| Elijah Chiang als Kid #1 (voice) |
| Cyrus Shaki-Khan als Kid #2 (voice) |
| Ted Elliott | Screenplay |
| Terry Rossio | Screenplay |
| Hans Zimmer | Original Music Composer |
| John Carnochan | Supervising Film Editor |
| John Powell | Original Music Composer |
| Jeffrey Katzenberg | Executive Producer |
| Jeffrey Katzenberg | Co-Director |
| Leslee Feldman | Casting |
| Elton John | Music |
| Dan Molina | Supervising Film Editor |
| Brooke Breton | Producer |
| Karey Kirkpatrick | Additional Dialogue |
| Bonne Radford | Producer |
| Bibo Bergeron | Director |
| Bill Damaschke | Co-Executive Producer |
| Fabrice Joubert | Animation |
| James P. Lay | Sound Effects Editor |
| Michael Schlingmann | Animation |
| Paul Lasaine | Art Direction |
| Dave Kupczyk | Animation |
| Ronnie del Carmen | Story Artist |
| Andy Nelson | Sound Re-Recording Mixer |
| Adam Milo Smalley | Supervising Music Editor |
| Anna Behlmer | Sound Re-Recording Mixer |
| Gregory King | Sound Designer |
| Gregory King | Supervising Sound Editor |
| Yann Delpuech | Supervising Sound Effects Editor |
| Vicki Hiatt | Editor |
| Vicki Hiatt | Music Editor |
| Seth Engstrom | Layout |
| Darlie Brewster | Supervising Animator |
| Simon Otto | Animation |
| Jean-Francois Rey | Animation |
| Kevin Turcotte | Background Designer |
| Al Holter | Sequence Leads |
| Mick De Falco | Layout |
| James Baxter | Animation Supervisor |
| Luc Desmarchelier | Visual Development |
| Christian Schellewald | Production Design |
| Gabriele Zucchelli | Animation |
| Frans Vischer | Supervising Animator |
| Kristof Serrand | Animation Supervisor |
| Harald Kraut | Layout |
| Michael Isaak | Layout |
| Lorenzo E. Martinez | Layout Supervisor |
| Jeff Snow | Story Artist |
| Raymond Zibach | Art Direction |
| Stephen Wood | 2D Artist |
| Jill Hopper | Production Manager |
| Mark Swift | Production Manager |
| Bud Myrick | 3D Artist |
| Don Paul | Director |
| Damon O'Beirne | Layout Supervisor |
| Dan Philips | Digital Supervisor |
| David S. Karoll | Modeling |
| Wendell Luebbe | Art Direction |
