 | Dennis Quaid als Frank Towns |
 | Tyrese Gibson als AJ |
 | Giovanni Ribisi als Elliott |
 | Miranda Otto als Kelly |
 | Tony Curran als Rodney |
 | Sticky Fingaz als Jeremy |
 | Jacob Vargas als Sammi |
 | Hugh Laurie als Ian |
 | Scott Michael Campbell als Liddle |
 | Kevork Malikyan als Rady |
 | Jared Padalecki als Davis |
 | Paul Ditchfield als Dr. Gerber |
 | Martin Hindy als Newman |
 | Bob Brown als Kyle |
 | Anthony Brandon Wong als Lead Smuggler |
 | Derek Barton als Voice Actor (voice) |
 | Jim Lau als Voice Actor (voice) |
| Yi-ding Wang als Smuggler #2 |
| Kee-yick Cheng als Smuggler #3 |
| Vernon Lehmann als Smuggler #4 |
| Dennis McNeill | Color Timer |
| John Moore | Director |
| William Aldrich | Producer |
| Edward Burns | Screenplay |
| Brendan Galvin | Director of Photography |
| Wyck Godfrey | Producer |
| Don Zimmerman | Editor |
| John Davis | Producer |
| Scott Frank | Screenplay |
| Alex Blum | Producer |
| Ric Kidney | Executive Producer |
| Bill Abbott | Music Editor |
| Alan Hook | Art Direction |
| Tricia Wood | Casting |
| George L. Little | Costume Design |
| Deborah Aquila | Casting |
| Patrick Lumb | Production Design |
| James M. Churchman | Stunt Coordinator |
| David B. Nowell | Helicopter Camera |
| Gregory W. Smith | Steadicam Operator |
| Eliza Solesbury | Set Decoration |
| Des Whelan | Camera Operator |
| Matthew Sullivan | Set Decoration |
| Adam Cameron | Leadman |
| Adriana Dardas | Set Designer |
| Kevin Morrissey | Set Designer |
| Ciarán Barry | Camera Operator |
| Annette Keet | Makeup Artist |
| Karen M. Murphy | Visual Effects Producer |
| Egon Endrényi | Still Photographer |
| Bruce Bisbey | Art Department Coordinator |
| Jennifer Blatt | Assistant Art Director |
| Peter Brown | Sound Effects Editor |
| James Bolt | Sound Re-Recording Mixer |
| Jerry Pooler | Visual Effects Supervisor |
| Ron Berkeley | Makeup Artist |
| Dezi Rorich | Publicist |
| Christopher Bass | Art Direction |
| David Goldberg | Visual Effects Supervisor |
| Nada Pinter | Script Supervisor |
| Fiona Connon | Makeup Department Head |
| Scott Gordon | Visual Effects Supervisor |
| Kelly Nelson | Hairstylist |
| Bob Brown | Stunt Coordinator |
| Steve Dellerson | Visual Effects Producer |
| Michael McDermott | Gaffer |
| Tiffany Smith | Visual Effects Producer |
| Gary Nolin | Visual Effects Producer |
| Dan Zimmerman | First Assistant Editor |
| David Wilson | Publicist |
| Rick Findlater | Makeup Artist |
| Jay Wilkinson | Supervising Sound Editor |
| Derek Spears | Visual Effects Supervisor |
| Kelly L'Estrange | Visual Effects Producer |
| Darion Hing | Costume Supervisor |
| Skip Longfellow | First Assistant Sound Editor |
| Eric Pender | CG Supervisor |
| Mark Shoaf | CG Supervisor |
| Peter Belcher | Camera Operator |
| Marco Beltrami | Original Music Composer |
| Andrew Menzies | Supervising Art Director |
| Ryan Cosgrove | Art Department Assistant |
| Geraldine Jones | Hair Department Head |
| John Ash | Electrician |
| Beverley House | Key Hair Stylist |
| Wallace David February | Painter |
| Lance Peters | Armorer |
| Jason Frazier | Stand In |
| William Boston | Orchestrator |
| Kevin Greene | Camera Technician |
| Buck Sanders | Additional Music |
| Simon Firsht | Boom Operator |
| Jack Cloete | Carpenter |
| Guy Nockels | Production Manager |
| Ian Voigt | Production Sound Mixer |
| Matthys Boshoff | Standby Painter |
| Patrick Esposito | Post-Production Manager |
| Charlie Davis | Post Production Supervisor |
| Richard Berkeley | Set Production Assistant |
| Danny Green | Assistant Director |
| John Eaves | Production Illustrator |
| Ana Alves | Video Assist Operator |
| Doug Hemphill | Sound Mixer |
| Judith Bell | Digital Compositors |
| Brad Peterman | First Assistant Camera |
| Daniel J. Lester | Assistant Costume Designer |
| John E. Gray | Special Effects Coordinator |
| Doc D. Charbonneau | Stunts |
| Lynette Ely | Production Coordinator |
| Jennifer L. Smith | Casting Associate |
| John Andrew Baker | Set Dressing Artist |
| Romek Delmata | Storyboard |
| Lonnie A. Mathes | Post Production Assistant |
| Anne C. Ford | Production Accountant |
| Lisa Spence | Digital Producer |
| Jean-Roux Viljoen | Unit Manager |
| Ric Kidney | Unit Production Manager |
| Mark Chavez | 3D Artist |
| Dani Leff | Visual Effects Coordinator |
| Shelly Kidney | Production Supervisor |
| John Kurlander | Scoring Mixer |
| James J. Atkinson | Lighting Supervisor |
| Robert Fischer | Grip |
| Jimmy N. Roberts | Stunt Coordinator |
| Dennis Rogers | Sound Recordist |
| Robert Troy | Dialogue Editor |
| Craig Heath | Sound Recordist |
| Tim Gomillion | Sound Recordist |
| Susan Dawes | Dialogue Editor |
| Mark Auret | Property Master |
| Sarah Trevis | Local Casting |
| Caitlin McKenna | ADR Voice Casting |
| Chris Jensen | Digital Colorist |
| Gary Burritt | Negative Cutter |
| Jeff Carson | Supervising Music Editor |
| Joni Jacobson | Digital Supervisor |
| Philip Murphy | Key Rigging Grip |
| Rowan Miles | Pilot |
| Carolyn Marston | Key Costumer |
| Stan Spry | Production Secretary |
| Sean Devereaux | Visual Effects Compositor |
| Desi Ortiz | Visual Effects Editor |
| Michele Perrone | ADR Editor |
| Derek Casari | ADR Engineer |
| Steve Austin | Special Effects Technician |
| Etienne Changuion | Stunt Double |
| Catherine Pantazopoulos | Colorist |
| Ferdi Burger | Second Second Assistant Director |
| Yaa Boaa Aning | Costumer |
| Doc Kane | ADR Mixer |
| Shahida April | Wardrobe Assistant |
| Curtis Lindersmith | Digital Intermediate Editor |
| Willem Bezuidenhout | Animal Wrangler |
| Andrew Silvestri | Matchmove Supervisor |
| Tilu Khalayi | Second Assistant Accountant |
| Etienne Smit | Swing |
| John Uribe | First Assistant Accountant |
| Dylan Cole | Matte Painter |
| John T. Cucci | Foley Artist |
| Pamela Choules | Assistant Editor |
| Deborah J. Chesebro | Assistant Accountant |
| Jac Joel | Draughtsman |
| Philip McKeon | Assistant Camera |
| Jennifer Ricchiazzi | Casting Assistant |
| Anthony Harris | Digital Color Timer |
| Scott Dougherty | Head of Production |
| Jimmy N. Roberts | Second Unit Director |
| Thomas Brown | Second Assistant Camera |
| Lewis Menga | Production Assistant |
| Pete Anthony | Conductor |
| Josh R. Jaggars | Digital Effects Producer |
| Adrienne Greshock | Costume Assistant |
| David Paris | Aerial Coordinator |
| Christopher Pace | Generator Operator |
| Vicki Routs | Set Dressing Buyer |
| David Lucarelli | ADR Recordist |
| Rodger Pardee | Sound Effects Designer |
| Telfer Barnes | Focus Puller |
| Alison van Biljon | Assistant Production Coordinator |
| Jeff Barnes | Production Executive |
| Boris Rivett-Carnac | Assistant Property Master |
| Dan O'Connell | Foley Artist |
| Jim Brookshire | ADR Supervisor |
| Terra Bliss | Digital Intermediate Producer |
| Lukas Heller | Scenario Writer |
| Casey O'Neill | Stunts |
| Dean Zimmerman | First Assistant Editor |
