 | Tim Allen als Jason Nesmith |
 | Sigourney Weaver als Gwen DeMarco |
 | Alan Rickman als Alexander Dane |
 | Tony Shalhoub als Fred Kwan |
 | Sam Rockwell als Guy Fleegman |
 | Daryl Mitchell als Tommy Webber |
 | Enrico Colantoni als Mathesar |
 | Robin Sachs als Sarris |
 | Jed Rees als Teb |
 | Justin Long als Brandon |
 | Missi Pyle als Laliari |
 | Patrick Breen als Quellek |
 | Jeremy Howard als Kyle |
 | Sam Lloyd als Neru |
 | Rainn Wilson als Lahnk |
 | J.P. Manoux als Excited Alien |
 | Dian Bachar als Nervous Tech |
 | Heidi Swedberg als Brandon's Mom |
 | Kevin McDonald als Announcer (as Kevin Hamilton McDonald) |
 | Kaitlin Cullum als Katelyn |
| Jonathan Feyer als Hollister |
 | Corbin Bleu als Young Tommy |
 | Isaac C. Singleton Jr. als Sarris' Guard |
 | Joel McKinnon Miller als Warrior Alien |
 | Todd Giebenhain als Teen in the Bathroom #2 |
| Jerry Penacoli als Reporter |
 | Jennifer Manley als Shy Girl |
 | Matt Winston als Technician #1 |
 | Marcio Rosario als Sarri's Guard (uncredited) |
 | Morgan Rusler als Fan #2 |
| Dean Parisot | Director |
| David Howard | Screenplay |
| Mark Johnson | Producer |
| Charles Newirth | Producer |
| David Newman | Original Music Composer |
| Jerzy Zielinski | Director of Photography |
| Don Zimmerman | Editor |
| Debra Zane | Casting |
| Linda DeScenna | Production Design |
| James Nedza | Art Direction |
| Ric McElvin | Set Decoration |
| Albert Wolsky | Costume Design |
| Charles Newirth | Unit Production Manager |
| J.J. George | Music Editor |
| Keith Marbory | Special Effects Coordinator |
| William N. Greene III | Special Effects |
| Mat Beck | Visual Effects Supervisor |
| David S. Dranitzke | Visual Effects |
| Andy Armstrong | Stunt Coordinator |
| James Armstrong | Utility Stunts |
| Robert Gordon | Screenplay |
| Robert Q. Mathews | Costume Supervisor |
| David Newman | Orchestrator |
| Jeff Carson | Music Supervisor |
| Ashley Fardys | Art Department Coordinator |
| Terri Taylor | Casting Associate |
| George L. Little | Assistant Costume Designer |
| Joy Zapata | Hair Department Head |
| Alan D'Angerio | Hairstylist |
| Ve Neill | Makeup Department Head |
| Bill Corso | Makeup Artist |
| Hallie D'Amore | Makeup Artist |
| Richard Beggs | Sound Designer |
| J.R. Grubbs | Sound Effects Editor |
| Tim Nielsen | Sound Effects Editor |
| Karen G. Wilson | Sound Effects Editor |
| Lora Hirschberg | Sound Re-Recording Mixer |
| Tom Johnson | Sound Re-Recording Mixer |
| Tim Holland | Supervising Sound Editor |
| Claire Graybill | Dialogue Editor |
| Ewa Sztompke | Dialogue Editor |
| Kerry Lyn McKissick | Script Supervisor |
| Hugh Waddell | ADR Supervisor |
| Jessica Gallavan | ADR Editor |
| Jayme S. Parker | ADR Editor |
| Dean Drabin | ADR Mixer |
| Cary Stratton | ADR Recordist |
| Bruce Lacey | Foley Editor |
| Frank Rinella | Foley Recordist |
| Marnie Moore | Foley Artist |
| Margie O'Malley | Foley Artist |
| Jerry Moss | Property Master |
| Murray Close | Still Photographer |
| Lee Orloff | Production Sound Mixer |
| Andy Armstrong | Second Unit Director |
| James Armstrong | Assistant Director |
| Phil Dupont | Second Assistant Director |
| Kristin Killey | Second Second Assistant Director |
| Vincent Lascoumes | First Assistant Director |
| Wayne D. Barlowe | Concept Artist |
| Robert Fechtman | Set Designer |
| Nancy Gilmore | Leadman |
| Thomas Meikle | Sculptor |
| Andrew Petrotta | Assistant Property Master |
| Dawn Swiderski | Set Designer |
| Sally Thornton | Assistant Art Director |
| Butch West | Costume Coordinator |
| Nicholas R. Allen | Boom Operator |
| Lesley Aletter | Stunt Double |
| John Casino | Stunt Double |
| Kofi Elam | Stunt Double |
| Toby Holguin | Stunt Double |
| Tanner Gill | Stunts |
| William D. Barber | Camera Operator |
| David Boyd | Second Unit Director of Photography |
| Alejandro J. Castillo | Lighting Technician |
| Tom Connole | Camera Operator |
| Fred Cooper | Dolly Grip |
| Glenn Corbett | Rigging Gaffer |
| Brian LeGrady | First Assistant Camera |
| Duane Mieliwocki | Assistant Camera |
| Brian H. Reynolds | Key Grip |
| Rafael E. Sánchez | Gaffer |
| Kirby Washington | Second Assistant Camera |
| Mari Grimaud | Key Costumer |
| Gary Burritt | Negative Cutter |
| Sven E. Fahlgren | Post Production Coordinator |
| Dale E. Grahn | Color Timer |
| Debra James | Production Coordinator |
| Paul LaZebnik | Assistant Production Coordinator |
| Cheryl A. Stone | Production Accountant |
| Christi Robbins | Production Secretary |
| Alex L. Worman | Unit Publicist |
| Allegra Clegg | Associate Producer |
| Janet Lewin | Associate Producer |
| Roxy D'Alonzo | Makeup Artist |
| Marie Del Prete | Makeup Artist |
| Chris Hanson | Special Effects Makeup Artist |
| Mark Landon | Makeup Artist |
| Steve LaPorte | Special Effects Makeup Artist |
| Gilbert A. Mosko | Makeup Artist |
| Douglas Noe | Prosthetic Makeup Artist |
| Brian Penikas | Prosthetics |
| Deborah Rutherford | Makeup Artist |
| Rick Stratton | Makeup Artist |
| Stan Winston | Makeup Effects |
| Erica Frauman | Post Production Supervisor |
| Stefen Fangmeier | Second Unit Director |
| Michele Panelli-Venetis | Second Unit First Assistant Director |
| Tory Belleci | Modeling |
| Adam Savage | Modeling |
| Grant Imahara | Modeling |
| Spice Williams-Crosby | Stunts |
| Jennifer Caputo | Stunts |
| Dana Dru Evenson | Stunts |
| Laura Albert | Stunts |
| Dane Farwell | Stunts |
| Doc Duhame | Stunts |
| Leon Delaney | Utility Stunts |
| Tanner Gill | Utility Stunts |
| Dennis Fitzgerald | Utility Stunts |
| Gary Guercio | Utility Stunts |
| Jim Palmer | Stunts |
| Will Leong | Stunts |
| Mark Stefanich | Stunts |
| Casey Pieretti | Utility Stunts |
| Mike Stokey | Stunts |
| Nils Allen Stewart | Stunts |
| Raliegh Wilson | Utility Stunts |
| Jesse V. Johnson | Stunts |
| Freddie Joe Farnsworth | Stunts |
| JD Roberto | Stunts |
| Mark Aaron Wagner | Stunt Double |
| Craig Lyn | CG Artist |
| Dean Zimmerman | Assistant Editor |
