 | Bruce Lee als Billy Lo |
 | Gig Young als Jim Marshall |
 | Dean Jagger als Dr. Land |
 | Hugh O'Brian als Steiner |
 | Colleen Camp als Ann Morris |
 | Robert Wall als Carl Miller |
 | Mel Novak als Stick |
 | Kareem Abdul-Jabbar als Hakim |
 | Chuck Norris als Colt |
 | Dan Inosanto als Pasqual |
 | Billy McGill als John |
 | Sammo Hung als Lo Chen |
 | Roy Chiao als Henry Lo |
| Kim Tae-Jeong als Billy Lo |
 | James Tien Chuen als Charlie Wang |
 | Wang Ho als Lau Yea-chun (archive footage) |
 | Bolo Yeung |
 | Yuen Biao als Billy Lo |
 | Robert Clouse als Carl's Second #1 (uncredited) |
| Warwick Paul Evans als Ringside Commentator (uncredited) |
 | Lam Ching-Ying als Macau Fighter (uncredited) |
 | Mars als Macau Fighter (uncredited) |
 | Nora Miao als (archive footage) (uncredited) |
 | André E. Morgan als (uncredited) |
 | Betty Ting Pei als (uncredited) |
 | Yuen Wah als Lo Chen's Second (uncredited) |
 | Paul Chung Fat als (uncredited) |
 | Stephen Chang als Ming Tao (uncredited) |
 | Lau Kar-Wing als (uncredited) |
 | Jim James als Surgeon |
 | Austin Wai Tin-Chi |
| Robert Clouse | Director |
| Robert Clouse | Writer |
| Raymond Chow Man-Wai | Producer |
| André E. Morgan | Associate Producer |
| John Barry | Original Music Composer |
| Godfrey A. Godar | Director of Photography |
| Alan Pattillo | Editor |
| Jackie Chan | Stunts |
| Tadashi Nishimoto | Director of Photography |
| Catherine S.K. Chang | Assistant Art Director |
| Graham Freeborn | Makeup Artist |
| Huang Shun-Chang | Property Master |
| Danny Daniel | Sound Mixer |
| Ken Dufva | Foley Artist |
| Mark Eggenweiler | Assistant Sound Editor |
| William L. Stevenson | Supervising Sound Editor |
| Kim Tae-Jeong | Stunt Double |
| Yuen Biao | Stunts |
| Yuen Biao | Stunt Double |
| Bruce Lee | Producer |
| David Chan | Production Manager |
| Sam Wong | Unit Manager |
| Mike Gowans | First Assistant Director |
| Bryan Levinge | Second Assistant Director |
| Sam Yip | Second Assistant Director |
| Mars | Stunt Double |
| Robert Wall | Stunt Coordinator |
| Sammo Hung | Stunt Coordinator |
| Sammo Hung | Stunts |
| Robert Wall | Stunts |
| Yuen Wah | Stunts |
| William H. Burton Sr. | Stunt Driver |
| David R. Ellis | Stunt Driver |
| Buddy Joe Hooker | Stunt Driver |
