 | Jane Fonda als Georgia Randall |
 | Lindsay Lohan als Rachel Wilcox |
 | Felicity Huffman als Lilly |
 | Dermot Mulroney als Dr. Simon Ward |
 | Cary Elwes als Arnold |
 | Garrett Hedlund als Harlan Wilson |
 | Hector Elizondo als Izzy |
 | Dylan McLaughlin als Sam |
 | Zachary Gordon als Ethan |
 | Laurie Metcalf als Paula Richards |
 | Hope Alexander-Willis als Fern |
 | Chelse Swain als June Smith |
 | Adreana Gonzalez als Izzy's Niece |
 | Fred Applegate als Townie #1 |
| Cynthia Ferrer als Townie #2 |
 | Paul Williams als Mr. Wells |
 | Christine Lakin als Grace Cunningham |
 | Shea Curry als Pig Owner Melody |
 | Rance Howard als Dog Bite Man |
 | Beth Kennedy als Fat Dog Owner |
 | Scott Marshall als Man Kissing Dog |
 | Barbara Marshall als Store Owner |
 | Shane Partlow als Cowboy |
| Cassie Rowell als Potato Queen |
| Garry Marshall | Director |
| Jake Rice | Editorial Manager |
| Karl Walter Lindenlaub | Director of Photography |
| Tara Timpone | Editor |
| James G. Robinson | Producer |
| Michael Besman | Executive Producer |
| Kevin Reidy | Executive Producer |
| Bruce Green | Editor |
| Mark Andrus | Writer |
| Guy McElwaine | Executive Producer |
| John Debney | Music |
| Albert Brenner | Production Design |
| Norman Newberry | Art Direction |
| Garrett Lewis | Set Decoration |
| Bonnie Timmermann | Co-Producer |
| David Robinson | Producer |
| Meegan E. Godfrey | Stunts |
| Pam Dixon | Casting |
| Lynn Barber | Makeup Department Head |
| Donna J. Anderson | Hair Department Head |
| Daniel Curet | Hair Department Head |
| Kimberly Greene | Makeup Artist |
| Lana Horochowski | Makeup Artist |
| Richard Marin | Hairstylist |
| Emanuel Millar | Hairstylist |
| Robin Siegel | Makeup Artist |
| Dorothy J. Pearl | Makeup Artist |
| Melissa Yonkey | Hairstylist |
| Dan Genetti | Post Production Supervisor |
| Lynn Andrews | Production Supervisor |
| Scott Marshall | Second Unit Director |
| Tommy Harper | First Assistant Director |
| Bill Purple | Second Assistant Director |
| Donald J. Malouf | Supervising Sound Editor |
| G.W. Brown | ADR Supervisor |
| Terry Porter | Sound Re-Recording Mixer |
| Thomas Causey | Sound Mixer |
| Dean A. Zupancic | Sound Re-Recording Mixer |
| Todd Toon | Supervising Sound Editor |
| Travis Baumann | Visual Effects Supervisor |
| Larz Anderson | Special Effects Coordinator |
| Austen Brewer | Stunts |
| Pat Banta | Stunts |
| Charlie Brewer | Stunt Coordinator |
| Jennifer Caputo | Stunts |
| Mickey Giacomazzi | Stunts |
| Eddie Hice | Stunts |
| Deborah L. Mazor | Stunts |
| James M. Halty | Stunts |
| Brad McCabe | Stunts |
| Kym Stys | Stunts |
| Katie Rowe | Stunts |
| Scott Wilder | Stunt Coordinator |
| Deborah L. Mazor | Stunt Double |
| Christian Sebaldt | Second Unit Director of Photography |
| Ronald Batzdorff | Still Photographer |
| Gary Jones | Costume Designer |
| Dawn Solér | Music Supervisor |
| Kevin Reidy | Unit Production Manager |
