 | Nicolas Cage als Johnny Blaze / Ghost Rider |
 | Eva Mendes als Roxanne Simpson |
 | Sam Elliott als Carter Slade / Phantom Rider |
 | Wes Bentley als Blackheart / Black King |
 | Peter Fonda als Mephistopheles / Mephisto |
 | Matt Long als Young Johnny Blaze |
 | Brett Cullen als Barton Blaze |
 | Raquel Alessi als Young Roxanne Simpson |
 | Donal Logue als Mack |
 | Tony Ghosthawk als Team Blaze |
 | Hugh Sexton als Team Blaze |
 | Marcus Jones als Team Blaze |
 | Lawrence Cameron Steele als X Games Announcer |
 | Eddie Baroo als Motorcycle Gang Member |
 | Jessica Napier als Broken Spoke Waitress |
 | Rebel Wilson als Goth Girl in Alley |
 | Daniel Frederiksen als Wallow |
 | Mathew Wilkinson als Abigor |
 | David Roberts als Captain Dolan |
| Matt Norman als Team Blaze |
| Peter Barry als The Mugger |
| Peter Callan als Station Master |
| Duncan Young als Skinhead |
 | Ryan Johnson als Waiter |
| Gibson Nolte als Stuart |
 | Joel Tobeck als Redneck |
| Jeanne McCarthy | Casting |
| David S. Goyer | Executive Producer |
| Richard Francis-Bruce | Editor |
| Michael De Luca | Producer |
| Stan Lee | Executive Producer |
| Avi Arad | Producer |
| Christopher Young | Original Music Composer |
| Peter Russell | Art Direction |
| Lisa Brennan | Property Master |
| Dane A. Davis | Sound Designer |
| Dane A. Davis | Supervising Sound Editor |
| Juel Bestrop | Casting |
| Christine King | Casting |
| Gary Foster | Producer |
| Lizzy Gardiner | Costume Design |
| Kirk M. Petruccelli | Production Design |
| Mark Steven Johnson | Screenplay |
| Mark Steven Johnson | Director |
| Steven Paul | Producer |
| Ilona Herman | Makeup Artist |
| Russell Boyd | Director of Photography |
| E. Bennett Walsh | Executive Producer |
| Richard Hobbs | Supervising Art Director |
| Suza Maybury | Set Decoration |
| Gary Archer | Prosthetics |
| Leilani Hannah | "B" Camera Operator |
| Ryan Nicholson | Makeup Effects |
| John Dunn | Sound Effects Editor |
| David A. Whittaker | Sound Effects Editor |
| Lesley Vanderwalt | Hairstylist |
| Brad Shield | Second Unit Director of Photography |
| Matt Corrigan | Makeup Effects |
| Gary A. Hecker | Foley |
| Peter Collias | Scenic Artist |
| Owen Walstrom | Stunts |
| Margot Ready | Assistant Art Director |
| Donald Flick | Sound Effects Editor |
| Eric Lindemann | Sound Effects Editor |
| Michael J. Broomberg | Foley |
| Tony Lees | Sculptor |
| Greg Hedgepath | Sound Effects Editor |
| Bill R. Dean | Sound Effects Editor |
| Greg Orloff | Sound Re-Recording Mixer |
| Gary C. Bourgeois | Sound Re-Recording Mixer |
| Jennifer Stanfield | Hairstylist |
| Kate Birch | Hairstylist |
| Kevin Scott Mack | Visual Effects Supervisor |
| Stephanie Flack | Dialogue Editor |
| Miles Teves | Conceptual Design |
| David A. Cohen | Dialogue Editor |
| Jenny Hitchcock | Set Designer |
| Katherine Brown | Makeup Effects |
| Ian Richter | Scenic Artist |
| Bobbi Banks | ADR & Dubbing |
| Dave Elsey | Makeup Effects |
| Ferdinando Merolla | Hairstylist |
| Liz Harper | Makeup Artist |
| Louise Coulston | Makeup Artist |
| Ayma Letang | Makeup Effects |
| Jason Ward | Makeup Effects |
| Tim Lyall | Art Department Coordinator |
| Peta Ross | Construction Coordinator |
| Marcus Smith | Construction Coordinator |
| Matthew Cotter | Sculptor |
| Simon Coke | Sound Effects Editor |
| Caroline Kelly | Special Effects Coordinator |
| Mark Goellnicht | Steadicam Operator |
| Mark Goellnicht | "A" Camera Operator |
| David Elmes | First Assistant "A" Camera |
| Brett Matthews | First Assistant "B" Camera |
| Warwick Field | Aerial Director of Photography |
