 | Ricky Gervais als Dr. Bertram Pincus |
 | Greg Kinnear als Frank Herlihy |
 | Téa Leoni als Gwen Herlihy |
 | Billy Campbell als Richard |
 | Aasif Mandvi als Dr. Jahangir Prashar |
 | Dana Ivey als Marjorie Pickthall |
 | Kristen Wiig als Surgeon |
 | Michael-Leon Wooley als Hospital Lawyer |
 | Alan Ruck als Ghost Dad |
 | Jordan Carlos als Young Husband |
 | DeQuina Moore als Young Wife |
 | Joseph Badalucco Jr. als Accident Bystander #1 |
 | Brian Hutchison als Accident Bystander #2 |
| Tyree Michael Simpson als Sneezy Cop |
 | Julia K. Murney als Sneezy Lady |
 | Claire Lautier als Upper East Side Lady |
| Bridget Moloney als Receptionist |
 | Raymond J. Lee als Greenpeace Guy |
 | Joey Mazzarino als Food Delivery Guy |
 | Brad Oscar als Day Doorman |
| Kathleen Landis als Resident |
 | Audrie Neenan als Admitting Nurse |
 | Aaron Tveit als Anesthesiologist |
 | Deborah S. Craig als Nurse |
 | Betty Gilpin als WWII Nurse |
| Angelis Alexandris als Elderly Couple |
 | Elaine Kussack als Elderly Couple |
 | Brian Tarantina als Ghost Cop |
 | Darren Pettie als Construction Worker Ghost |
 | Jesse Means als Construction Worker Ghost |
 | Robert Kelly als Construction Worker Ghost |
| Gabrielle Fink als Violin Student |
 | Monte Bezell als Cab Driver |
 | Sebastian La Cause als Bartender |
| Miles Grose als Night Doorman |
 | Jeff Hiller als Naked Guy Ghost |
 | Lou Sumrall als Harley Guy Ghost |
 | Raymond McAnally als Assorted Ghost |
| Amy Van Nostrand als Assorted Ghost |
 | Ira Hawkins als Assorted Ghost |
 | Danai Gurira als Assorted Ghost |
| Richard O'Rourke als Man at Lecture |
 | Brian d'Arcy James als Irish Eddie |
| Jazz als Other Leonard |
| Josh Clayton als Waiter |
 | Lisa Datz als Happy Person in Bar |
| James Ludwig als Happy Person in Bar |
 | Melissa Thomas als Dr. Prashar's Patient |
| Shan Hill als Bongo Player |
 | Megan Byrne als Mrs. Pickthall's Daughter |
 | José Ramón Rosario als Crane Operator |
 | Jose Soto als Welder |
| Candace Thompson als Harley Guy's Old Lady |
 | Dylan Clark Marshall als Little Alex |
| Alex Eckstein als Mrs. Pickthall's Grandson (uncredited) |
| Tina King als Nurse (uncredited) |
| Nicholas Julius als Orderly (uncredited) |
| John Ahrens als Jogger Ghost (uncredited) |
| Christina Russo als Elevator Ghost (uncredited) |
 | Marmee Regine Cosico als Ghost (uncredited) |
| Ezie Cotler als Ghost (uncredited) |
| John Kamps | Screenplay |
| David Koepp | Director |
| Gavin Polone | Producer |
| Joseph E. Iberti | Producer |
| Gary Barber | Executive Producer |
| Roger Birnbaum | Executive Producer |
| Ezra Swerdlow | Executive Producer |
| Geoff Zanelli | Original Music Composer |
| Sam Seig | Editor |
| Patricia McCorkle | Casting |
| John Papsidera | Casting |
| Howard Cummings | Production Design |
| Fred Murphy | Director of Photography |
| Joseph E. Iberti | Unit Production Manager |
| Joseph E. Iberti | Co-Producer |
| Jeffrey T. Bernstein | First Assistant Director |
| Nancy Herrmann | Second Assistant Director |
| Jeffrey Lee Gibson | Stunt Coordinator |
| Nicholas Lundy | Art Direction |
| Caroline Vexler | Stunts |
| Bill Anagnos | Stunts |
| Jill Brown | Stunts |
| John R. Favre | Stunts |
| Don Hewitt Sr. | Stunts |
| Matt Norklun | Stunts |
| Keith Siglinger | Stunts |
| Jay Spadaro | Stunts |
| Bobby Beckles | Stunts |
| John Cenatiempo | Stunts |
| Michael Patrick Gough | Stunt Double |
| Jalil Jay Lynch | Stunts |
| Janet Paparazzo | Stunts |
| Brian Smyj | Stunts |
| Aaron Vexler | Stunts |
| Tom Warren | Assistant Art Director |
| Debra Schutt | Set Decoration |
| Bruce MacCallum | Camera Operator |
| Eric Swanek | First Assistant Camera |
| Michael Cambria | Second Assistant Camera |
| Andrew Peck | Loader |
| Stephen Consentino | Steadicam Operator |
| Angela Bellisio | Second Assistant "B" Camera |
| Brian C. Mackey | Loader |
| Sarah Shatz | Still Photographer |
| Mary Bailey | Script Supervisor |
| James Sabat | Production Sound Mixer |
| James J. Sabat Jr. | Cableman |
| Dan Paikin | Boom Operator |
| Nils Johnson | Video Assist Operator |
| Russell Engels | Chief Lighting Technician |
| James M. Mah | Assistant Chief Lighting Technician |
| Christian Baldi | Assistant Chief Lighting Technician |
| John Leigh | Electrician |
| John M. Gilgar | Electrician |
| Josh Taylor | Electrician |
| Timothy Healy | Electrician |
| Robert M. Andres | First Company Grip |
| Chris Skutch | Second Company Grip |
| Arthur Blum | Dolly Grip |
| Alison Barton | Grip |
| Ben D'Andrea | Grip |
| Graham Klatt | Grip |
| John Halligan | Grip |
| Vinny Mazzarella | Property Master |
| Joseph Badalucco Jr. | Assistant Property Master |
| Tonero Williams | Props |
| Steven Kirshoff | Special Effects Coordinator |
| Wilfred Caban | Special Effects Technician |
| Devin Maggio | Special Effects Technician |
| Roy Savoy | Special Effects Technician |
| John Stifanich | Special Effects Technician |
| Emily Gunshor | Assistant Costume Designer |
| Kate Edwards | Costume Supervisor |
| Fionnuala Lynch | Costumer |
| Rose Marie Cappelluti | Costumer |
| Kevin P. Faherty | Costumer |
| Melissa Haley | Costume Coordinator |
| Lori Hicks | Makeup Department Head |
| Michele Paris | Key Makeup Artist |
| Sacha Quarles | Hair Department Head |
| Christine Fennell | Key Hair Stylist |
| Daisy Curbeon | Hairstylist |
| Kent Blocher | First Assistant Editor |
| Susan Lazarus | Post Production Supervisor |
| Leda Nornang | Post Production Coordinator |
| Matthew F. Preston | Assistant Production Coordinator |
| Talia Mayer | Production Secretary |
| Matilde P. Bandini | Production Accountant |
| Antonia Proscia | First Assistant Accountant |
| Carolyn J. White | Second Assistant Accountant |
| Salpy Semerdjian | Second Assistant Accountant |
| Albert Valera | Payroll Accountant |
| Evan Perazzo | Location Manager |
| Jason Farrar | Assistant Location Manager |
| Josh Dorn | Assistant Location Manager |
| Rob Roy | Location Coordinator |
| Ted O'Connor | Second Second Assistant Director |
| Jennifer Cram | Casting Associate |
| Joe Lopick | Casting Associate |
| Dylan Jury | Casting Assistant |
| Lauren Sullivan | Casting Assistant |
| Peter J. Silbermann | Unit Publicist |
| Tina Khayat | Art Department Coordinator |
| Justin Elterman | Graphic Designer |
| Lauren Oliver | Clearances Coordinator |
| Brick Mason | Storyboard Artist |
| Alexandra Mazur | Assistant Set Decoration |
| Debbie Canfield | Set Dresser |
| Chris Canfield | Set Dresser |
| Christopher Ferraro | Set Dresser |
| Richard K. Hoppe | Set Dresser |
| Brian Jones | Set Dresser |
| Christopher Heads | Set Dresser |
| Nick Miller | Construction Coordinator |
| Philip Canfield | Leadman |
| Ruth DeLeon | On Set Dresser |
| James P. Whalen | Transportation Captain |
| Joseph Buonocore | Transportation Co-Captain |
| Joseph S. Marini | Technical Advisor |
| Lauren Weissman | Producer's Assistant |
| Emily Davis | Producer's Assistant |
| Marlena Thomas | Executive Producer's Assistant |
| Kim Buttlar | Executive Producer's Assistant |
| Robert Hein | Supervising Sound Editor |
| Michael Barry | Sound Re-Recording Mixer |
| Robert Hein | Sound Re-Recording Mixer |
| Brian Bowles | ADR Editor |
| Glenfield Payne | Sound Effects Editor |
| Robert Fernandez | Sound Effects Editor |
| Zana Bochar | Post Production Assistant |
| Maureen Beitler | Medical Consultant |
| Michael Patrick Gough | Stand In |
| D Comer | Stand In |
| Monica McCarthy | Stand In |
| Genevieve Palmieri Metzger | Key Production Assistant |
| Sean Murray | Production Assistant |
| Maggie Delaney | Production Assistant |
| Travis Gerdes | Production Assistant |
| Connor Jones | Production Assistant |
| Marissa Vrooman | Production Assistant |
| Tim Goldberg | Production Assistant |
| Andrew Finn | Production Assistant |
| Robert Tierney | Production Assistant |
| Miriam Tielmann | Production Assistant |
| Kate Lundberg | Production Assistant |
| Tom Berninger | Production Assistant |
| Abimael Jackson-Viana | Production Assistant |
| T.G. Wilkinson | Production Assistant |
| Sarah Edwards | Costume Design |
| David Koepp | Screenplay |
| Bob Barnett | Charge Scenic Artist |
| David Wahnon | Sound Editor |
| Carlos Cano | Assistant Sound Editor |
| Matthew Haasch | Foley Editor |
| Ryan Collison | Foley Mixer |
| Bobby Johanson | ADR Mixer |
| David Boulton | ADR Mixer |
| Doc Kane | ADR Mixer |
| Nick Kray | ADR Mixer |
| Michael Miller | ADR Mixer |
| Mike Howells | ADR Recordist |
| Krissopher Chevannes | ADR Recordist |
| Joseph S. DeBeasi | Music Editor |
| Bruce Fowler | Conductor |
| Walt Fowler | Orchestrator |
| Yvonne S. Moriarty | Orchestrator |
| Michael O'Donovan | Musician |
| Steve Erdody | Musician |
| Don Markese | Musician |
| George Doering | Musician |
| Geoff Zanelli | Musician |
| James S. Levine | Musician |
| Arman Matin | Visual Effects Supervisor |
| Jim Rider | Compositing Supervisor |
| Cara Buckley | Visual Effects Producer |
| Tim Stipan | Digital Intermediate Colorist |
| Dana Bloder | Digital Intermediate Producer |
| Randall Balsmeyer | Title Designer |
| J. John Corbett | Compositor |
| Tricia Chiarenza | Color Timer |
| René González | Projection |
| David H. Kramer | ADR Coordinator |
| Jay Peck | Foley Artist |
| Piotr Glabinski | Modeling |
