 | Kyle Chandler als Mark Russell |
 | Vera Farmiga als Emma Russell |
 | Millie Bobby Brown als Madison Russell |
 | Ken Watanabe als Dr. Ishiro Serizawa |
 | Zhang Ziyi als Dr. Ilene Chen / Dr. Ling |
 | Bradley Whitford als Dr. Rick Stanton |
 | Sally Hawkins als Dr. Vivienne Graham |
 | Charles Dance als Alan Jonah |
 | Thomas Middleditch als Sam Coleman |
 | Aisha Hinds als Colonel Diane Foster |
 | O'Shea Jackson Jr. als Chief Warrant Officer Barnes |
 | David Strathairn als Admiral William Stenz |
 | Anthony Ramos als Staff Sergeant Martinez |
 | Elizabeth Faith Ludlow als First Lieutenant Griffin |
 | Jonathan Howard als Asher Jonah |
 | CCH Pounder als Senator Williams |
 | Joe Morton als Dr. Houston Brooks |
 | Randy Havens als Dr. Tim Mancini |
 | Lyle Brocato als Executive Officer Bowman |
 | Jimmy Gonzales als Commander Crane |
 | T.C. Matherne als Master Sergeant Hendricks |
 | Kenneth Israel als Argo Deck Officer Zellner |
 | Justice Leak als Monarch Officer Martin |
 | Al Vicente als Isla de Mara Fisherman |
 | Rose Bianco als Isla de Mara Grandmother |
 | Gabriel L. Silva als Isla de Mara Grandson |
 | Skylar Denney als Argo Officer Arvin |
 | Kelli Garner als Argo Officer Cross |
 | Tyler Crumley als Young Andrew |
 | Lexi Rabe als Young Madison |
 | Zac Zedalis als Sergeant Travis |
 | Tracie Garrison als Asaj |
 | Natalie Shaheen als Lieutenant Bottin |
 | Jesse O'Neill als Corporal Winston |
 | Joshua Leary als Sergeant Baker |
 | Vince Foster als G-Team Officer Tippett |
 | Shauna Rappold als G-Team Officer Harryhausen |
 | Fiona Hardingham als News Anchor #1 |
 | Orelon Sidney als News Anchor #2 |
 | Paul Ryden als News Anchor #3 |
 | Laurie Dhue als News Anchor #4 |
 | Kevin Shinick als Weather Man |
 | T.J. Storm als Godzilla Performance Capture |
 | Jason Liles als King Ghidorah Performance Capture |
| Alan Maxson als King Ghidorah Performance Capture |
| Richard Dorton als King Ghidorah Performance Capture |
 | Seth Green als Fighter Pilot (uncredited) |
 | Eli Roth als Fighter Pilot (uncredited) |
| James William Ballard als Mercenary (uncredited) |
 | Joey Beni als Lt. Gentry (uncredited) |
| Gerardo Bosco als Isla de Mara Fat Runner (uncredited) |
 | Madeline Brumby als G-Team (uncredited) |
| John David Bulla als Jonah's Mercenary #2 (uncredited) |
| Hans Bush als Colonel Bush (uncredited) |
 | Marko Caka als Jonah's Mercenary #9 (uncredited) |
 | Andrea Antonio Canal als Argo Crew (uncredited) |
 | Timothy Carr als Emt (uncredited) |
 | Greg Clarkson als Anchor #5 (uncredited) |
 | Michael Dougherty als Fighter Pilot (uncredited) |
 | Robin Dyke als Monarch Scientist (uncredited) |
 | Fred Galle als Egan (uncredited) |
| Christopher Bryan Gomez als Monarch Scientist (uncredited) |
 | Clare Grant als Fighter Pilot (uncredited) |
| Anthony B. Harris als National Guard Soldier (uncredited) |
| Kasia Hart als Sonogram Technician (uncredited) |
| Cecil M. Henry als Ausprey Refueler (uncredited) |
| Maxwell Highsmith als Scientist (uncredited) |
 | Mallory Hoff als Reporter #5 (uncredited) |
| Brian Kayode-Patrick Johnson als Boston Evacuee (uncredited) |
| Andrea Maiuro als Village Fisherman (uncredited) |
| Van Marten als Dr. Chen's Assistant (uncredited) |
| Shaun McLane als Submarine Pilot (uncredited) |
 | Shaun McMillan als Aircraft Ground Crew (uncredited) |
 | Roger K. Moore als Military Special Forces (uncredited) |
 | Tony Morgan als Monarch Scientist (uncredited) |
 | Stephen Moyer als Fighter Pilot (uncredited) |
| Leiloni Arrie Pharms als Terrified Little Girl (uncredited) |
 | Sasha Rionda als Reporter (uncredited) |
| Diana Rombola als Argo Crew (uncredited) |
| Andres Salgado als Isis Guard (uncredited) |
 | Zach Shields als Fighter Pilot (uncredited) |
| Beverley Simmons als Senator (uncredited) |
| Max Soliz als Village Fisherman (uncredited) |
| Thomas W. Stewart als Argo Crew (uncredited) |
 | Joey Thurmond als Scientist (uncredited) |
| Miguel Angel Varela Fimbres als Street Scaping Daring Tourist (uncredited) |
 | Buddy Watkins als Grounds Crew / Base Gaurd (uncredited) |
 | Benjamin Weaver als Deck Officer (uncredited) |
 | Jamie Wedel als Deck Commander (uncredited) |
 | Michael David Yuhl als Paramedic (uncredited) |
| Sarah Halley Finn | Casting |
| Lawrence Sher | Director of Photography |
| Bob Ducsay | Editor |
| Richard L. Johnson | Supervising Art Director |
| Richard Pearson | Editor |
| Louise Mingenbach | Costume Designer |
| Paul Hughen | Second Unit Director of Photography |
| Barry H. Waldman | Executive Producer |
| Barry H. Waldman | Unit Production Manager |
| Roger Barton | Editor |
| Scott Chambliss | Production Design |
| Michael Dougherty | Screenplay |
| Michael Dougherty | Director |
| Michael Dougherty | Story |
| Roy Lee | Executive Producer |
| Jane Oshita | Stunts |
| Joe Bucaro III | Stunts |
| Peter Afterman | Music Supervisor |
| Margaret Yen | Music Supervisor |
| Thomas Tull | Producer |
| Bear McCreary | Original Music Composer |
| T.J. Storm | Motion Capture Artist |
| Jon Jashni | Producer |
| Dan Lin | Executive Producer |
| Joel Harlow | Makeup Department Head |
| Alex Garcia | Producer |
| Mary Parent | Producer |
| Serj Tankian | Musician |
| Dick Ziker | Stunt Double |
| Richard Dorton | Motion Capture Artist |
| Zack Duhame | Stunts |
| Yoshimitsu Banno | Executive Producer |
| Yoshimitsu Banno | In Memory Of |
| Haruo Nakajima | In Memory Of |
| Whit Norris | Sound Mixer |
| Brian Rogers | Producer |
| Thomas Lappin | "B" Camera Operator |
| Bradley Parker | Visual Effects |
| Stacy Perskie | Co-Producer |
| Max Borenstein | Story |
| Alan Maxson | Motion Capture Artist |
| Brandon Jones | Sound Designer |
| Brooklyn Proctor | Stunts |
| Thomas Robinson Harper | Stunt Coordinator |
| Thomas Robinson Harper | Second Unit Director |
| Nancy Nugent | Supervising Sound Editor |
| Kenji Okuhira | Executive Producer |
| Tim Walston | Sound Designer |
| Brice Liesveld | Visual Effects Producer |
| Tom Ozanich | Sound Re-Recording Mixer |
| Hallie Ricardo | Stunts |
| Agnes Mayasari | Stunts |
| Erik Aadahl | Sound Designer |
| Ethan van der Ryn | Sound Designer |
| Tim LeBlanc | Sound Re-Recording Mixer |
| Amanda Moss Serino | Set Decoration |
| Yolanda Toussieng | Hair Department Head |
| Jason W. Jennings | Supervising Sound Editor |
| Christopher TJ McGuire | Steadicam Operator |
| Christopher TJ McGuire | "A" Camera Operator |
| Daniel C. McFadden | Still Photographer |
| Gerardo Moreno | Stunt Coordinator |
| Guillaume Rocheron | Visual Effects Supervisor |
| Zach Shields | Screenplay |
| Zach Shields | Executive Producer |
| Zach Shields | Story |
| Amy Lynn Tuttle | Stunts |
| Dean Sherriff | Conceptual Design |
| Gregory Irwin | First Assistant "A" Camera |
| Lee Ann Brittenham | Hair Department Head |
| Maricel Pagulayan | Visual Effects Producer |
| Maricel Pagulayan | Co-Producer |
| Adam Walls | Makeup Department Head |
| Marlie Arnold | Assistant Art Director |
| John Hewitt | Visual Effects |
| Janeshia Adams-Ginyard | Stunt Double |
| Scott Christopher Kelly | Stand In |
| Cliff Lanning | Co-Producer |
| Laurence Chavez | Stunts |
| Crystal Hooks | Stunt Double |
| Haley Nott | Stunts |
| Daniela Medeiros | Set Designer |
| Andy Hoehn | First Assistant "B" Camera |
| Ali Mendes | Co-Producer |
| Jason Liles | Motion Capture Artist |
| Danya Bateman | Stunts |
| Nicole Marines | Stunt Double |
| Santiago Núñez | Sound Mixer |
| Julia Maggio | Stunts |
| Julia Maggio | Stunt Double |
| Jerry Patton | Second Assistant "A" Camera |
| Keiji Ota | Executive Producer |
| Brian Connor | Visual Effects Supervisor |
| Chris Howland | Additional Production Sound Mixer |
| Nicholas Kay | Digital Imaging Technician |
| Rodney Gurulé | Sound Mixer |
| JoAnn Bernat | Stunts |
| Jessica Nam | Stunts |
| Ayami Sakaeda | Stunts |
| Kathryn Howard | Stunts |
| Kathryn Howard | Stunt Double |
| Michele Waitman | Stunts |
| Hiroyasu Matsuoka | Executive Producer |
| Paul E. Woods | Second Assistant "B" Camera |
| Hiroshi Mori | Visual Effects |
