 | Gibson Gowland als John McTeague |
 | Zasu Pitts als Trina |
 | Jean Hersholt als Marcus |
 | Dale Fuller als Maria |
 | Tempe Pigott als Mother McTeague |
 | Sylvia Ashton als Mommer Sieppe |
 | Chester Conklin als Popper Sieppe |
 | Joan Standing als Selina |
 | Jack Curtis als McTeague Sr. (uncredited) |
 | James F. Fulton als Cribbens a Prospector (uncredited) |
| Florence Gibson als Hag (uncredited) |
 | Cesare Gravina als Zwerkow a Junkman (uncredited) |
 | Frank Hayes als Charles W. Grannis (uncredited) |
| Austen Jewell als August Sieppe (uncredited) |
| Tiny Jones als Mrs. Heise (uncredited) |
| Lillian Lawrence als Gossip (uncredited) |
 | Hughie Mack als Mr. Heise (uncredited) |
 | Jack McDonald als Placer County Sheriff (uncredited) |
 | Fanny Midgley als Anastasia Baker (uncredited) |
 | Lon Poff als Lottery Agent (uncredited) |
| S.S. Simon als Joe Frenna (uncredited) |
| Erich von Ritzau als Dr. Painless Potter (uncredited) |
 | Erich von Stroheim als Balloon Vendor (uncredited) |
| James Wang als Chinese Cook (uncredited) |
| June Mathis | Screenplay |
| Frank Norris | Novel |
| Ben F. Reynolds | Director of Photography |
| Irving Thalberg | Producer |
| Erich von Stroheim | Director |
| Erich von Stroheim | Production Design |
| William H. Daniels | Director of Photography |
| Erich von Stroheim | Screenplay |
| Joseph Farnham | Editor |
| Cedric Gibbons | Art Direction |
| Erich von Stroheim | Art Direction |
| J.J. Cohn | Production Manager |
| Harry Rapf | Production Manager |
| Edward Sowders | Assistant Director |
| Cedric Gibbons | Set Decoration |
| Louis Germonprez | Assistant Director |
| Richard Day | Art Direction |
| Warren Lynch | Still Photographer |
| William Axt | Original Music Composer |
| Frank E. Hull | Editor |
| Joseph Farnham | Title Graphics |
| James V. King | Projection |
| Ernest B. Schoedsack | Camera Operator |
| Louis B. Mayer | Executive Producer |
| Leo Kempinski | Music |
| Paul Ivano | Camera Operator |
