 | Will Smith als Alex 'Hitch' Hitchens |
 | Eva Mendes als Sara Melas |
 | Kevin James als Albert Brennaman |
 | Amber Valletta als Allegra Cole |
 | Julie Ann Emery als Casey Sedgewick |
 | Adam Arkin als Max |
 | Robinne Lee als Cressida Baylor |
 | Nathan Lee Graham als Geoff |
 | Michael Rapaport als Ben |
 | Jeffrey Donovan als Vance Munson |
 | Paula Patton als Mandy |
 | Philip Bosco als Mr. O'Brian |
 | Kevin Sussman als Neil |
 | Navia Nguyen als Mika |
 | Matt Malloy als Pete |
 | Maria Christina Thayer als Lisa |
 | Ato Essandoh als Tanis |
 | Marlyne Barrett als Stephanie |
 | Jack Hartnett als Tom Reda |
 | David Wike als Chip |
 | Frederick B. Owens als Larry |
 | Jenna Stern als Louise |
 | Austin Lysy als Magnus “Maggie” Forester |
 | Adam LeFevre als Speed Dating Guy |
 | Joe Lo Truglio als Music Lover Guy |
 | Ryan Cross als Charles Wellington |
 | Beau Sia als Drugstore Clerk |
 | Fran Kranz als Coca Cola Guy (uncredited) |
 | Amy Hohn als Marla |
 | Mimi Weddell als Grandma Wellington |
 | Caprice Benedetti als Gorgeous Wife |
 | Rain Phoenix als Kate |
 | Anya Avaeva als Hot Date |
 | Brielle Barbusca als Student on Class Trip |
| Kimberly Cash als Kissing Girl |
| Valbona Coba als Bar Girl |
| Michelle Carlsen |
 | Michelle DiBenedetti als First Date Woman |
| Alexa Lane als Yoga Student |
| Christina Lauren als Bar Girl |
 | Rebecca Mader als Kim |
| Amy Metroka als Female Speed Dater |
| Maria Nomi als Club Girl |
| Jennifer Pedersen als Bar Girl |
| Keri Uribe als Sara's Nosey Officemate |
| Olivia Weston als Beautiful Yatch Owner |
| Dianne Zaremba als Sara's Co-Worker |
| Joanna Lu als Elevator Girl (uncredited) |
| Mercedes Renard als Maria |
 | Tony Travis als Tony |
 | Ptolemy Slocum als Ron |
| Andrew Dunn | Director of Photography |
| George Fenton | Original Music Composer |
| Tracey Wadmore-Smith | Editor |
| Kevin Bisch | Screenplay |
| Will Smith | Producer |
| James Lassiter | Producer |
| Andy Tennant | Director |
| Troy Takaki | Editor |
| Joseph S. Alfieri | Construction Coordinator |
| Henry Antonacchio | Construction Foreman |
| Frank Ferrara | Stunt Coordinator |
| Peter Bucossi | Stunt Coordinator |
| Al Cerullo | Pilot |
| Roy T. Anderson | Stunts |
| Greg Wattkis | Stunts |
| Janet Paparazzo | Stunts |
| Jodi Michelle Pynn | Stunts |
| Gino Lucci | Stunts |
| Justin Moritt | Unit Production Manager |
| Scott Printz | First Assistant Director |
| Michael Pitt | Second Assistant Director |
| Patricia Woodbridge | Art Direction |
| Ellen Christiansen | Set Decoration |
| Martin Lasowitz | Property Master |
| Robin Squibb | Script Supervisor |
| Kathleen Chopin | Casting |
| Michael Tadross | Executive Producer |
| Wink Mordaunt | Executive Producer |
| Marlene Stewart | Costume Design |
| Jane Musky | Production Design |
| Teddy Zee | Producer |
| David Knox | "A" Camera Operator |
| Jim McConkey | "B" Camera Operator |
| Jim McConkey | Steadicam Operator |
| Larry Huston | First Assistant "A" Camera |
| Mark Schwartzbard | Second Assistant "A" Camera |
| Geb Byers | First Assistant "B" Camera |
| Lee Kazista | Second Assistant "B" Camera |
| Christopher Peterson | Assistant Costume Designer |
| Ira M. Hammons-Glass | Assistant Costume Designer |
| Pashelle Clayton-Robinson | Costume Supervisor |
| Winsome G. McKoy | Costume Supervisor |
| Marta Font | Key Costumer |
| Tommy Boyer | Costumer |
| Judy Murdock | Makeup Department Head |
| Toy Van Lierop | Key Makeup Artist |
| Richard Dean | Makeup Artist |
| Pierce Austin | Hair Department Head |
| Brian Sherratt | Hairstylist |
| Kenneth Walker | Hairstylist |
| Rod Ortega | Hairstylist |
| Gene Engels | Chief Lighting Technician |
| Steve Comesky | Assistant Chief Lighting Technician |
| Francis J. McBride | Rigging Gaffer |
| George Patsos | Key Grip |
| Keith Bunting | Dolly Grip |
| James V. Gartland | Dolly Grip |
| Billy Patsos | Key Rigging Grip |
| T.J. O'Mara | Production Sound Mixer |
| Joe White | Boom Operator |
| Kim Maitland | Boom Operator |
| Michelle Mader | Video Assist Operator |
| Paul Kramer | Location Manager |
| Terry Ladin | Production Coordinator |
| Kory O'Donnell | Assistant Production Coordinator |
| Nadine F. Wilson | Production Accountant |
| Jacq Donegan | Production Secretary |
| Barbra Matis | Set Designer |
| Toni Barton | Assistant Art Director |
| Darrell K. Keister | Assistant Art Director |
| Addison Pettit | Assistant Art Director |
| Alyson Wellins | Art Department Coordinator |
| Dave Weinman | Leadman |
| Michael Jortner | Assistant Property Master |
| Julie Kuehndorf | Unit Publicist |
| Barry Wetcher | Still Photographer |
| Murphy Occhino | Second Second Assistant Director |
| Robert Dickerson Jr. | Additional Second Assistant Director |
| Eric Zuckerman | Casting Associate |
| Meredith Jacobson Marciano | Extras Casting |
| Steven R. Hammond | Transportation Captain |
| Peter Clores | Transportation Co-Captain |
| Frank Capra III | Second Unit Director |
| Matt Evans | First Assistant Editor |
| George Watters II | Supervising Sound Editor |
| Suhail Kafity | Supervising Sound Editor |
| R.J. Palmer | Sound Effects Editor |
| Gary Wright | Sound Effects Editor |
| F. Hudson Miller | Sound Effects Editor |
| Douglas Parker | Assistant Sound Editor |
| Melissa Lytle | Assistant Sound Editor |
| Ron Vignone | Assistant Sound Editor |
| Teri E. Dorman | Supervising Dialogue Editor |
| Ulrika Akander | Dialogue Editor |
| Allen Hartz | Dialogue Editor |
| Gloria D'Alessandro | Dialogue Editor |
| Christopher T. Welch | ADR Supervisor |
| Andrea Horta | ADR Editor |
| Susan Kurtz | ADR Editor |
| Victoria Martin | Foley Editor |
| Matthew Harrison | Foley Editor |
| Brian Ruberg | Foley Mixer |
| Gary A. Hecker | Foley Artist |
| Nancy Parker | Foley Artist |
| Howard London | ADR Mixer |
| Paul J. Zydel | ADR Mixer |
| Jeffrey J. Haboush | Sound Re-Recording Mixer |
| Bill W. Benton | Sound Re-Recording Mixer |
| Barbara Harris | ADR Voice Casting |
| Michael T. Ryan | Music Editor |
| Skip Kimball | Digital Color Timer |
| Mo Henry | Negative Cutter |
| Mat Beck | Visual Effects Supervisor |
| Eli Jarra | Digital Effects Supervisor |
| Leighton Greer | Visual Effects Producer |
| Mark Alan Loso | Compositor |
| Angela M. Catanzaro | Assistant Editor |
