 | Lea Thompson als Beverly Switzler |
 | Jeffrey Jones als Dr. Walter Jenning |
 | Tim Robbins als Phil Blumburtt |
 | Ed Gale als Howard T. Duck |
 | Holly Robinson Peete als K.C., Cherry Bomb |
 | David Paymer als Larry, Scientist |
 | Paul Guilfoyle als Lieutenant Welker |
 | Richard Edson als Ritchie |
 | Dominique Davalos als Cal, Cherry Bomb |
 | Liz Sagal als Ronette, Cherry Bomb |
 | Chip Zien als Howard T. Duck (voice) |
 | Tommy Swerdlow als Ginger Moss |
 | Miles Chapin als Carter |
 | Richard McGonagle als First Cop |
 | Virginia Capers als Cora Mae, Secretary |
 | Debbie Lee Carrington als Additional Ducks |
 | Miguel Sandoval als Bar Entertainment Supervisor |
 | Sheldon Feldner als Hot Tub Spa Owner |
 | Paul Comi als Dr. Chapin |
 | James Lashly als State Trooper |
 | William Hall als Officer Hanson |
 | John Fleck als Pimples |
 | Nancy Fish als Homeless Bag Lady |
 | Wood Moy als Chef |
 | Kristopher Logan als Punk |
 | Brandon Erickson als *uncredited* Man on bike |
| Willard Huyck | Director |
| Gloria Katz | Screenplay |
| Sidney Wolinsky | Editor |
| Michael Chandler | Editor |
| Willard Huyck | Screenplay |
| John Barry | Original Music Composer |
| Richard H. Kline | Director of Photography |
| George Lucas | Executive Producer |
| Gloria Katz | Producer |
| Phil Tippett | Visual Effects |
| Phil Tippett | Creature Design |
| Don Ruffin | Stunts |
| Ben Burtt | Sound Effects Editor |
| Randy Thom | Sound Re-Recording Mixer |
| Ben Burtt | Sound Re-Recording Mixer |
| Michael J. McAlister | Visual Effects Supervisor |
| Randy Thom | Sound Designer |
| Gary Summers | Sound Re-Recording Mixer |
| Robert Latham Brown | Production Manager |
| Richard Hashimoto | Production Manager |
| Dan Kolsrud | First Assistant Director |
| Patrick Cosgrove | Second Assistant Director |
| L. Dean Jones Jr. | Second Assistant Director |
| Phillip Norwood | Visual Effects Art Director |
| Louise Jaffe | Script Supervisor |
| Thomas J. Wright | Second Unit Director |
| Bobby Byrne | Second Unit Director of Photography |
| Everett Creach | Stunt Coordinator |
| Mark Billerman | Art Direction |
| Blake Russell | Art Direction |
| Harley Jessup | Assistant Production Design |
| John Warnke | Assistant Art Director |
| Jim Pohl | Set Designer |
| Pamela Marcotte | Set Designer |
| Chuck Roseberry | Production Assistant |
| Phil Abramson | Set Decoration |
| Jim Poynter | Leadman |
| Robert Krume | Construction Coordinator |
| Robert Bonino | Construction Foreman |
| Stacey S. McIntosh | Construction Foreman |
| Dwight Williams | Construction Foreman |
| Christopher Brooks | Supervising Music Editor |
| Gloria S. Borders | Supervising Sound Editor |
| Rory Enke | Location Manager |
| Steve Gerber | Characters |
| Gracie Atherton | Makeup Artist |
| Peter Jamison | Production Design |
| Bob Herron | Stunts |
| John Watson | Assistant Editor |
| Debbie Lee Carrington | Stunts |
| Thomas Dolby | Songs |
