 | Anthony Ramos als Usnavi |
 | Corey Hawkins als Benny |
 | Leslie Grace als Nina Rosario |
 | Melissa Barrera als Vanessa |
 | Olga Merediz als Abuela Claudia |
 | Daphne Rubin-Vega als Daniela |
 | Gregory Diaz IV als Sonny |
 | Marc Anthony als Gapo |
 | Jimmy Smits als Kevin Rosario |
 | Stephanie Beatriz als Carla |
 | Dascha Polanco als Cuca |
 | Noah Catala als Graffiti Pete |
 | Lin-Manuel Miranda als Piragüero |
 | Mateo Gómez als Alejandro |
 | Patrick Page als Pike |
 | Olivia Perez als Iris |
 | Analia Gomez als Rosa |
 | Dean Scott Vazquez als Sedo |
 | Mason Vazquez als Miggy |
 | Delila Ramos als Cranky Vieja |
 | Valentina als Self |
 | Christopher Jackson als Mr. Softee Truck Driver |
 | Susan Pourfar als Hannah Hathaway |
| María Hinojosa als Protest Leader |
 | Ryan Woodle als Mover |
 | Doreen Montalvo als Neighbor Lady |
 | Ilia Jessica Castro als Jessica from the Salon |
| Yesy Garcia als Woman in Lobby |
| Jonathan Arana als Salon Customer |
| Jennifer Hernandez als Bad-Ass Girl |
| Amp Ngernrungruangroj als Hipster |
| Bairam Rizai als Young Professional Couple |
| Lavinia Jones Wright als Young Professional Couple |
| Alexandra Campos als Cab Service Dispatcher |
| Rhapsody James als Salon Customer 1 |
| Ariana S. Gomez als Young Nina |
 | Ariana Greenblatt als Young Nina |
| Hugh M Jones III als Man Washing Car |
| Luis Miranda als Man in Street (uncredited) |
 | Javier Muñoz als Man in Street (uncredited) |
 | The Kid Mero als DJ (voice) (uncredited) |
 | Seth Stewart als Bartender (uncredited) |
| Jon M. Chu | Director |
| Mitchell Travers | Costume Design |
| Scott Sanders | Producer |
| Quiara Alegría Hudes | Producer |
| Andrew Baseman | Set Decoration |
| Nelson Coates | Production Design |
| Lin-Manuel Miranda | Producer |
| Mara Jacobs | Producer |
| Anthony Bregman | Producer |
| Lin-Manuel Miranda | Songs |
| Lin-Manuel Miranda | Lyricist |
| Lin-Manuel Miranda | Musical |
| Quiara Alegría Hudes | Musical |
| Quiara Alegría Hudes | Screenplay |
| Lin-Manuel Miranda | Idea |
| David Nicksay | Executive Producer |
| Kevin McCormick | Executive Producer |
| Myron Kerstein | Editor |
| Alex Lacamoire | Executive Music Producer |
| Bill Sherman | Executive Music Producer |
| Christopher Scott | Choreographer |
| Alex Lacamoire | Original Music Composer |
| Alice Brooks | Director of Photography |
| Jill Furman | Executive Producer |
| Jeffrey Seller | Executive Producer |
| Kevin McCollum | Executive Producer |
| Joseph P. Reidy | Co-Producer |
| Steven Gizicki | Music Supervisor |
| Mark Russell | Visual Effects Supervisor |
| Tiffany Little Canfield | Casting |
| Bernard Telsey | Casting |
| Maggie Engelhardt | Unit Production Manager |
| David Nicksay | Unit Production Manager |
| Joseph P. Reidy | First Assistant Director |
| John Silvestri | Second Assistant Director |
| Lin-Manuel Miranda | Original Music Composer |
| Bill Sherman | Original Music Composer |
| Scott Burik | Stunt Coordinator |
| Gregory Zuk | Associate Producer |
| Alexandra Torterotot | Script Supervisor |
| Chris Shriver | Supervising Art Director |
| Mark Schmidt | "A" Camera Operator |
| Mark Schmidt | Steadicam Operator |
| Peter Agliata | "B" Camera Operator |
| Denise Bailie | "C" Camera Operator |
| Drew Kunin | Sound Mixer |
| Michael Primmer | Boom Operator |
| Charlie Grubbs | Chief Lighting Technician |
| Kevin Lowry | Key Grip |
| Thomas Bianco | Production Accountant |
| Martha Melendez | Makeup Department Head |
| Stephanie Barr | Key Makeup Artist |
| Betsy Reyes | Hair Department Head |
| Valerie Velez | Key Hair Stylist |
| Brian Goodwin | Art Direction |
| Vinny Mazzarella | Property Master |
| Macall B. Polay | Still Photographer |
| Kristian Charbonier | Casting Associate |
| Grant Wilfley | Background Casting Director |
| Melissa Braun | Background Casting Director |
| Leigh Ann Smith | Casting Assistant |
| Grace Ward | Casting Assistant |
| Elisa Tallerico | Makeup Artist |
| Amy Duskin | Makeup Artist |
| Rae Dawn J Brooks | Makeup Artist |
| Donyale McRae | Makeup Artist |
| Christine Domaniecki | Makeup Artist |
| Guy Smith | Makeup Artist |
| Annemarie Bradley | Hairstylist |
| Olivia Del Campo | Production Coordinator |
| Olimpia T. Rinaldi | First Assistant Accountant |
| Basil Smith | First Assistant "A" Camera |
| Gavin Fernandez | First Assistant "B" Camera |
| Marvin Lee | Second Assistant "A" Camera |
| Caroline Ibarra | Second Assistant "B" Camera |
| Bjorn G. Jackson | Digital Imaging Technician |
| Sean P. Gilbert | Underwater Camera |
| Vincent Pierce | Best Boy Grip |
| Wil Hamlin | Dolly Grip |
| William Jones | Dolly Grip |
| Ian O'Neill | Dolly Grip |
| Sally Foster | Grip |
| Hunter Powers Middleton | Grip |
| Diandra Farquharson | Grip |
| Joe Coppola | Assistant Property Master |
| Jeremy W. Foil | Assistant Art Director |
| Katya Blumenberg | Assistant Art Director |
| Matthew Jeffrey Sama | Assistant Art Director |
| Clifton Leach | Assistant Art Director |
| Hugh Landwehr | Assistant Art Director |
| Sha-Sha Shiau | Art Department Coordinator |
| Ashley Wellbrock | Assistant Set Decoration |
| Alison Diviney | Set Decorating Coordinator |
| Samson Jacobson | Location Manager |
| Leila Nurse | Assistant Location Manager |
| Sarah Brady Stack | Assistant Location Manager |
| Doyle Lewis | Assistant Location Manager |
| Jessi Partridge | Location Coordinator |
| Jeff Brink | Special Effects Coordinator |
| Frances Fiore | Unit Publicist |
| Rachel Jaros | Second Second Assistant Director |
| Anna Swando | Second Second Assistant Director |
| Jim Popper | Transportation Captain |
| Dan Buckman | Transportation Co-Captain |
| Gary Kochakian | Driver |
| James Canavan | Driver |
| Joseph Fay | Driver |
| Joseph Falletta | Driver |
| Peter Ludwig | Driver |
| Joseph Reynolds | Driver |
| Andrew Pang | First Assistant Editor |
| Stephen Nakamura | Digital Intermediate Colorist |
| Gina Kalim | Digital Intermediate Editor |
| Lewis Goldstein | Sound Re-Recording Mixer |
| John Marquis | Sound Re-Recording Mixer |
| Paul Urmson | Additional Sound Re-Recording Mixer |
| Lewis Goldstein | Supervising Sound Editor |
| Gina Alfano | Supervising ADR Editor |
| Brian Bowles | Supervising Dialogue Editor |
| Tom Ryan | Dialogue Editor |
| Andrew Mastronardi | Sound Effects Editor |
| Wen Hsuan Tseng | Sound Effects Editor |
| Alex Soto | Sound Effects Editor |
| Leslie Bloome | Foley Artist |
| Joanna Fang | Foley Artist |
| Connor Nagy | Foley Mixer |
| Ryan Collison | Foley Mixer |
| Laura Heinzinger | Foley Editor |
| Nick Seaman | Foley Editor |
| Alfred DeGrand | Assistant Sound Editor |
| Jerrell Suelto | ADR Mixer |
| Aaron Southerland | ADR Mixer |
| Vinny Alfano | ADR Mixer |
| Eric Gotthelf | ADR Mixer |
| Tami Treadwell | ADR Mixer |
| Jim Bruening | Music Editor |
| Jennifer Dunnington | Music Editor |
| Thomas Kail | Thanks |
| Andy Blankenbuehler | Thanks |
| Denise Agius | Set Dresser |
| Greg Aharoni | Set Dresser |
| Jim Bauer | Set Dresser |
| Kim Shek | Set Costumer |
| Kate Smith | Costume Supervisor |
| Mitchel Wolf | Costume Coordinator |
