 | Liam Hemsworth als Jake Morrison |
 | Jeff Goldblum als David Levinson |
 | Jessie T. Usher als Dylan Hiller |
 | Bill Pullman als President Whitmore |
 | Maika Monroe als Patricia Whitmore |
 | Sela Ward als President Lanford |
 | Judd Hirsch als Julius Levinson |
 | William Fichtner als General Adams |
 | Brent Spiner als Dr. Brakish Okun |
 | Patrick St. Esprit als Secretary of Defense |
 | Vivica A. Fox als Dr. Jasmine Hiller |
 | AngelaBaby als Rain Lao |
 | Charlotte Gainsbourg als Dr. Catherine Marceaux |
 | Deobia Oparei als Dikembe |
 | Nicolas Wright als Floyd Rosenberg |
 | Travis Tope als Charlie Miller |
 | Chin Han als Commander Jiang Lao |
 | Gbenga Akinnagbe als Agent Matthew Travis |
 | Robert Loggia als General Grey |
 | John Storey als Dr. Isaacs |
 | Joey King als Sam |
 | Jenna Purdy als Voice of Sphere |
 | Garrett Wareing als Bobby |
 | Hays Wellford als Felix |
 | Mckenna Grace als Daisy |
 | James A. Woods als Lt. Ritter |
 | Robert Neary als Captain McQuaide |
 | Joshua Mikel als Armand |
 | Joel Virgel als Jaques |
 | Arturo del Puerto als Bordeaux |
 | Matthew Munroe als Prison Tech |
 | Jacob Browne als Prison Tech |
 | Ryan Cartwright als Officer Ryan Collins |
 | Travis Hammer als Jeffrey Fineman |
 | Lance Lim als Kevin |
 | Zeb Sanders als Camper Henry |
 | Donovan Tyee Smith als Camper Marcus |
 | Stafford Douglas als Flight Officer |
| Jade Scott Lewis als Salt Flat Tech |
 | Beth Bailey als Nurse |
 | Mona Malec als DC Hospital Nurse |
| Omar Diop als African Guard |
 | Ron Yuan als Yeong |
 | Grace Huang als Lin Tang |
 | Stephen Oyoung als Young Man |
| J.P. Murrieta als Local Reporter |
 | Casey Messer als Local Reporter |
 | Ben Wang als Chinese President |
 | Nicholas Ballas als French President |
| Jonathan Richards als British Prime Minister |
 | Ivan G'Vera als Russian President |
 | Sam Quinn als Radar Officer |
 | Richard Beal als Military Brass (uncredited) |
 | Alice Rietveld als Secret Service Agent (uncredited) |
 | Alma Sisneros als Aide 2 (uncredited) |
 | Kenny Leu als Ping Li (uncredited) |
 | Monique Candelaria als Tech Officer (uncredited) |
 | Leilei Chen als Background (uncredited) |
 | Ava Del Cielo als Young Mother (uncredited) |
 | Diana Gaitirira als Comms Officer (uncredited) |
| Evan Bryn Graves als Pilot P. Goodman (uncredited) |
 | Jason E. Hill als Marine (uncredited) |
 | Catharine E. Jones als Flight Officer (uncredited) |
 | Tyler Kurtz als Pilot (uncredited) |
 | Aaron Tyler als Tug Pilot (uncredited) |
| Michael Davis als Old Man with Oxygen |
 | Johnny Otto als Secret Service Agent (uncredited) |
 | John Christian Love als Officer |
| Roland Emmerich | Director |
| Dean Devlin | Screenplay |
| Roland Emmerich | Screenplay |
| Thomas J. Larsen | Stunts |
| David Greene | Special Effects Coordinator |
| Caty Maxey | Art Direction |
| Christa Munro | Art Direction |
| Laurent Ben-Mimoun | Conceptual Design |
| Red Rose Connerty | Seamstress |
| Darryl Garcia Jr. | Set Costumer |
| Richard Roles | Helicopter Camera |
| Carlos-Christian Nickel | CG Supervisor |
| Ronnie Menahem | CG Supervisor |
| Richard T. Olson | Art Department Coordinator |
| Rachel Bris | Set Costumer |
| Matt Fausak | Music Editor |
| Jay Kemp | Gaffer |
| Michael Scott Baker | Hairstylist |
| Eamonn Butler | Animation Director |
| Christopher Downs | CG Supervisor |
| Marion Spates | Digital Effects Supervisor |
| Michael Fournier | VFX Editor |
| James A. Woods | Screenplay |
| Harald Kloser | Producer |
| Markus Förderer | Director of Photography |
| Jo Edna Boldin | Casting |
| Lauren Abiouness | Art Direction |
| Christian Scheurer | Conceptual Design |
| Bill Holmquist | Construction Coordinator |
| Jess L. Johnson | Set Costumer |
| Mark Wendell | CG Supervisor |
| Alessandro Cangelosi | CG Supervisor |
| Dana Kay Hart | Costume Supervisor |
| Anele Onyekwere | Music Editor |
| Paul N.J. Ottosson | Sound Designer |
| Paul N.J. Ottosson | Supervising Sound Editor |
| Todd Busch | Visual Effects Editor |
| Marie A. Kohl | Casting Associate |
| Jennifer Bell | Hair Department Head |
| John O'Connell | 3D Supervisor |
| Thomas MacKenzie | Visual Effects Editor |
| Samantha Avila | Assistant Art Director |
| Lisy Christl | Costume Design |
| Sara Roybal | Makeup Artist |
| Ravi Bansal | Art Direction |
| Patrick M. Sullivan | Supervising Art Director |
| Chase Heard | Hairstylist |
| Jennifer M. Quinteros | Makeup Artist |
| Michael Minkler | Sound Re-Recording Mixer |
| Roland Emmerich | Producer |
| Lamarr Gray | Rigging Gaffer |
| Thomas Nellen | Makeup Department Head |
| Stuart Gordon Tribble | Makeup Artist |
| Alex Auriol | Animation Supervisor |
| Nicolas Wright | Screenplay |
| Harald Kloser | Original Music Composer |
| Tim Walker | Camera Operator |
| Evan Fisher | First Assistant Editor |
| Tammy S. Lee | Assistant Art Director |
| John Hoskins | Construction Coordinator |
| Oliver Hug | Music Editor |
| Lorette Leblanc | Script Supervisor |
| John Marzano | Helicopter Camera |
| Claudette Barius | Still Photographer |
| Mary Castor | Makeup Artist |
| Dean Devlin | Producer |
| Eric Sundahl | Art Direction |
| Deanna Brigidi | Casting Associate |
| James Goldman | Camera Operator |
| Holger Voss | VFX Supervisor |
| Adam Wolfe | Editor |
| Nancy A. King | Art Department Coordinator |
| Brian Malone | Rigging Grip |
| Dominik Zimmerle | VFX Supervisor |
| James Vanderbilt | Screenplay |
| Luis Guggenberger | Art Direction |
| Clint Wallace | Art Direction |
| Barry Chusid | Production Design |
| Jay Hart | Set Decoration |
| John Malmborg | Construction Coordinator |
| François Daignault | Camera Operator |
| Tom Reagan | Visual Effects Editor |
| Megan Daum | Key Hair Stylist |
| Jan Philip Cramer | Animation Director |
| Andy Stevens | Visual Effects Editor |
| Mary Iannelli | Assistant Costume Designer |
| Shanna Knecht | Assistant Costume Designer |
| Dylan Goss | Helicopter Camera |
| Chris M. Jacobson | Sound Effects Editor |
| Hamilton Sterling | Sound Effects Editor |
| Simone Kraus Townsend | Animation Supervisor |
| Liana Jackson | VFX Editor |
| Thomas Wanker | Original Music Composer |
| John Papsidera | Casting |
| Mark Hofeling | Art Direction |
| Delana Veirs | Hairstylist |
| Phil Barrie | Sound Effects Editor |
| Adrian Corsei | CG Supervisor |
| Andrew Roberts | CG Supervisor |
| Robert Loggia | In Memory Of |
| Larry Kemp | Dialogue Editor |
| Robert Troy | Dialogue Editor |
| Ronan Binding | Animation |
| Larry J. Franco | Unit Production Manager |
| Roland Emmerich | Story |
| Volker Engel | Co-Producer |
| Brendan Garst | Production Supervisor |
| Jason Pomerantz | Production Director |
| Larry J. Franco | Executive Producer |
| Duff Rich | Unit Production Manager |
| Jeffrey Harlacker | Post Production Supervisor |
| Carsten H.W. Lorenz | Unit Production Manager |
| Nathan E. Davis | Additional Second Assistant Director |
| Jeffrey Harlacker | Associate Producer |
| Ute Emmerich | Executive Producer |
| Amy Greene | Line Producer |
| Nathan L. Smith | Production Supervisor |
| Marco Shepherd | Co-Producer |
| Jason Miller | Post Production Supervisor |
| Dean Devlin | Story |
| K.C. Hodenfield | Co-Producer |
| Jonathan McGarry | First Assistant Director |
| Kevin Collins | Second Second Assistant Director |
| James A. Woods | Story |
| K.C. Hodenfield | First Assistant Director |
| Erin Bosley | Production Assistant |
| Nicolas Wright | Story |
| Carsten H.W. Lorenz | Executive Producer |
| Adrien Flanquart | VFX Artist |
| Shaila Tobin | Animation |
| Kimberly Harris | ADR Supervisor |
| John T. Cucci | Foley Artist |
| Michael J. Broomberg | Foley Artist |
| Jai James | Second Assistant Director |
| Dean Devlin | Characters |
| Roland Emmerich | Characters |
| Charlie Picerni | Stunt Driver |
| Paul Mercier | Vocals |
| Kelli Barksdale | Stunts |
| Keith Woulard | Stunts |
| Buddy Joe Hooker | Stunts |
| Scott Wilder | Stunts |
| Al Goto | Stunts |
| Ed Duran | Stunts |
| Tom Elliott | Stunts |
