 | Tessyo Genda als Frank Castle / The Punisher (voice) |
 | Keiji Fujiwara als Tony Stark / Iron Man (voice) |
 | Miyu Irino als Ezekiel Stane / Technovore (voice) |
 | Hiroe Oka als Pepper Potts (voice) |
 | Hiroki Yasumoto als James "Rhodey" Rhodes / War Machine (voice) |
 | Junko Minagawa als Maria Hill (voice) |
 | Miyuki Sawashiro als Natasha Romanoff / Black Widow (voice) |
 | Shuhei Sakaguchi als Clint Barton / Hawkeye (voice) |
 | Yasuyuki Kase als JARVIS (voice) |
 | Houko Kuwashima als Sasha Hammer (voice) |
 | Takaya Hashi als Obadiah Stane (voice) |
 | Hideaki Tezuka als Nick Fury (voice) |
 | Troy Baker als Clint Barton / Hawkeye / J.A.R.V.I.S. (English version, voice) |
 | Norman Reedus als Frank Castle / The Punisher (English version, voice) |
| Kengo Kaji | Screenplay |
| Brandon Auman | Story |
| Hiroshi Hamasaki | Director |
| Stan Lee | Characters |
| Taro Morishima | Producer |
| Jeph Loeb | Executive Producer |
| Joe Quesada | Co-Executive Producer |
| Harrison Wilcox | Producer |
| Megan Thomas Bradner | Producer |
| Hiroyuki Okada | Executive Producer |
| Alan Fine | Executive Producer |
| Stan Lee | Co-Executive Producer |
| Masao Takiyama | Executive Producer |
| Dan Buckley | Executive Producer |
| Simon Phillips | Executive Producer |
| Yasushi Nirasawa | Creature Design |
| Shigemi Ikeda | Art Direction |
| Mariko Tsukatsune | Editor |
| Shingo Natsume | Other |
| Kashiko Kimura | Editor |
| Takaharu Ozaki | Conceptual Design |
| Scott Dolph | Producer |
| Masafumi Mima | Sound Director |
| Satoshi Hashimoto | Color Designer |
| Kenichi Kawamura | Other |
| Hiroshi Hamasaki | Storyboard Artist |
| Iwao Teraoka | Storyboard Artist |
| Kenichi Kawamura | Storyboard Artist |
| Shingo Natsume | Storyboard Artist |
| Yoshiaki Kawajiri | Storyboard Artist |
| Romed Irmler | Background Designer |
| Tetsuya Takahashi | Original Music Composer |
| Masanori Shino | Character Designer |
