 | Denzel Washington als John Quincy Archibald |
 | James Woods als Dr. Raymond Turner |
 | Kimberly Elise als Denise Archibald |
 | Robert Duvall als Lt. Frank Grimes |
 | Shawn Hatosy als Mitch Quigley |
 | Eddie Griffin als Lester Matthews |
 | Kevin Connolly als Steve Maguire |
 | Ethan Suplee als Guard Max Conlin |
 | Ray Liotta als Chief Gus Monroe |
 | Anne Heche als Rebecca Payne |
 | Laura Harring als Gina Palumbo |
 | Heather Wahlquist als Julie Bird |
 | Daniel E. Smith als Mike Archibald |
 | David Thornton als Jimmy Palumbo |
 | Paul Johansson als Tuck Lampley |
 | Obba Babatundé als Sgt. Moody |
 | Troy Byer als Miriam Smith |
 | Troy Winbush als Steve Smith |
 | Martha Chaves als Rosa Gonzales |
 | Gabriela Oltean als Beautiful BMW Driver |
| Ron Annabelle als Tow Truck Driver |
| Barry G. King als Employee Manager |
 | Larissa Laskin als Dr. Ellen Klein |
 | Vanessa Branch als Registered Nurse |
 | Stephanie Moore als Admitting Nurse |
| James Finnerty als Nurse Reggie |
| Michael Jaye als Insurance Rep |
 | Yanna McIntosh als State Employee |
| Linda Massad als Social Services Rep |
| Lester Mathews als Human Services Rep |
 | Noam Jenkins als Medicaid Official |
 | Allegra Fulton als Sick Girl's Mother |
| Darrin Brown als TV Buyer |
 | Shera Danese als Wife of Heart Transplant Patient |
| Kirsta Teague als Dr. Turner's Assistant |
| Rick Sood als Panicked E.R. Doctor |
 | Scott Bloom als Desk Guard |
 | Dina Spybey-Waters als Debby Utley |
 | Carlos Diaz als Paramedic #1 |
| Joe Duer als Paramedic #2 |
 | Simon Sinn als Fong |
| Jeff Douglas als Computer Cop |
 | Keram Malicki-Sánchez als Freddy B. |
 | Philip Williams als Wally Pitoniak |
 | Nigel Shawn Williams als News Anchor |
 | Frank Cassavetes als Sniper |
| Colin Evans als Videographer |
 | Angelo Tsarouchas als Barricade Cop |
| Marcia Johnson als Medical Transplant #1 |
 | Vijay Mehta als Medical Transplant #2 |
 | Andrew Schaff als U.N.O.S. Official |
| Malcolm Nefsky als Nick |
 | Jay Leno als Jay Leno |
 | Gloria Allred als Gloria Allred |
 | Larry King als Larry King |
 | Arianna Huffington als Arianna Huffington |
 | Ted Demme als Ted Demme |
 | Nas als Nas |
 | Bill Maher als Bill Maher |
 | Claire Rankin als Public Defender |
 | Philip Craig als Judge K. Ploucha |
 | Gerry Quigley als Jury Foreman |
| Oren Koules | Producer |
| Avram Butch Kaplan | Executive Producer |
| Dede Allen | Editor |
| Rogier Stoffers | Director of Photography |
| James Kearns | Screenplay |
| Mark Burg | Producer |
| Aaron Zigman | Original Music Composer |
| Michael De Luca | Executive Producer |
| Nick Cassavetes | Director |
| Nancy Green-Keyes | Casting |
| Richard Saperstein | Executive Producer |
| Howard Burkons | Co-Executive Producer |
| James Kearns | Co-Producer |
| Mathew Hart | Co-Producer |
| Matthew Barry | Casting |
| Dale De La Torre | Co-Executive Producer |
| Beatrix Aruna Pasztor | Costume Design |
| Tom Fleischman | Sound Re-Recording Mixer |
| Michael Semanick | Sound Re-Recording Mixer |
| Stefania Cella | Production Design |
| Mike Flicker | Music Editor |
| Clive Thomasson | Set Decoration |
| Joanne T. Harwood | Script Supervisor |
| Peter Rosenfeld | Camera Operator |
| Ava Gerlitz | Still Photographer |
| Peter Rosenfeld | Steadicam Operator |
| David Lee | Production Sound Mixer |
| Terry Henderson | Chef |
| Lee Tucker | Technical Supervisor |
| Harry Muller | Color Timer |
| Pierce P. Shaad | Editorial Production Assistant |
| Lori Greenberg | Production Supervisor |
| Hector C. Gika | Sound Effects Editor |
| Saalahudeen Lunsford Muhammed | Security |
| Prudence Emery | Unit Publicist |
| George Venckus | Leadman |
| Alexandra Leviloff | First Assistant Editor |
| Mark Cowden | Best Boy Electric |
| Kim W. Chow | Set Costumer |
| Rick Avery | Stunt Coordinator |
| Jerry Hey | Orchestrator |
| Ken Dackermann | Digital Compositors |
| Elis Y. Lam | Art Direction |
| Nellie Adami | Production Office Coordinator |
| Jayson Clute | First Assistant Camera |
| Larry M. Cherry | Hairstylist |
| Jennifer Bower O'Halloran | Key Hair Stylist |
| Hillary Sherman | Co-Producer |
| Nicholas Gazda | Assistant Art Director |
| Ross Fraser | Construction Coordinator |
| Steve Fitzpatrick | Craft Service |
| Ron Annabelle | Picture Car Coordinator |
| William Chad Strug | Production Office Assistant |
| Jacqui Hemingway | Scenic Artist |
| Jill Fleischman | Stand In |
| Leslie Cowan | Production Coordinator |
| Rick Reynolds | Post Production Supervisor |
| Morgan Carpenter | Electrician |
| Denis Bellingham | Boom Operator |
| Gordon Brown | Painter |
| Neil Montgomerie | Transportation Coordinator |
| Christopher Brown | Video Assist Operator |
| Philippe Montel | Unit Manager |
| Thomas Carnegie | Art Direction |
| Andrea Kristof | Art Department Coordinator |
| Paul Spaven | Rigging Gaffer |
| Diana Adams | Production Accountant |
| Tony Kenny | Special Effects Supervisor |
| Michael Hyde | Construction Foreman |
| Nadia Ongaro | Seamstress |
| Steve Dewey | Additional Music |
| Mathew Hart | Unit Production Manager |
| Carla Fry | Executive In Charge Of Production |
| Wileen Dragovan | Location Manager |
| Nick Veziris | Gun Wrangler |
| Don Irvine | Rigging Grip |
| Lucie Fournier | Standby Painter |
| Charles Taylor | Armorer |
| Rudy Baccuchi | Driver |
| Roy T. Anderson | Stunts |
| Normand Viau | Gaffer |
| Nina Barry | Casting Associate |
| Matt Linder | 3D Supervisor |
| Jennifer Deigl | Set Production Assistant |
| Thomas Vance Jr. | Carpenter |
| Laurel Bresnahan | Studio Teachers |
| Paul Prokop | Production Controller |
| Dianne L. Haggarty | Grip |
| Chris Weiss | Camera Loader |
| Gerry Deschenes | Set Dresser |
| Mario Cacioppo | Key Makeup Artist |
| Barney Cabral | ADR Supervisor |
| Franco Tata | Chief Lighting Technician |
| Tracy Shaw | Dolly Grip |
| Kristen Ploucha | Second Assistant Director |
| Jesse Voccia | Music Programmer |
| Jimmy Zelinger | Title Designer |
| Dwayne McClintock | Aerial Director of Photography |
| Dan Monroe | Pilot |
| Inge Klaudi | Makeup Artist |
| Andrea Kool | Casting Assistant |
| Henry Jesiak | Assistant Property Master |
| Barbara Harris | ADR Voice Casting |
| Mark Manchester | Key Grip |
| Stacey S. Clipp | Associate Editor |
| William M. Connor | First Assistant Director |
| Mo Henry | Negative Cutter |
| Pierre Brunet | Assistant Production Manager |
| Sui Fan Wong | Utility Sound |
| Melissa Hall | Assistant Production Coordinator |
| Jennifer Mann | ADR Editor |
| Christopher Geggie | Property Master |
| James Moriana | Foley Artist |
| Frederick H. Stahly | Dialogue Editor |
| Greg Zimmerman | Foley Recordist |
| Laura Harris Atkinson | Dialogue Editor |
| Dean Drabin | ADR Mixer |
| Michelle Pazer | ADR Editor |
| Jeffrey Wilhoit | Foley Artist |
| Nerses Gezalyan | Foley Mixer |
| Carolyn Cox | Focus Puller |
| Robert J. Lemos | Assistant Editor |
| Alex Kontsalakis | Payroll Accountant |
| Donald Colafranceschi | Production Assistant |
| Vince Peets | Storyboard Artist |
| Kelly Cabral | Sound Supervisor |
| Mark Nener | Second Assistant Camera |
| Robert Batha | Sound Assistant |
| Melissa Morgan | Key Scenic Artist |
| Howard Stellmacher | Second Assistant Accountant |
| Jaclyn Shoub | Assistant Decorator |
| Jerry Hey | Conductor |
| Susan Haldenby | Technical Advisor |
| Brad Logel | Third Assistant Director |
| Earl Fligg | Assistant Location Manager |
| Louis-Martin Pepperall | Location Assistant |
| Gregory P. Fontana | Medical Consultant |
| Dianne Irving | Production Secretary |
| Jennifer Haufler | Assistant Director |
| Malcolm Nefsky | Best Boy Grip |
| Rick Gagnon | Location Production Assistant |
| Kristi Kasubaski | First Assistant Accountant |
| Andre Mayers | Stunt Double |
| Jean-François Boivin | Assistant Unit Manager |
| Kris Rurka | Extras Casting Assistant |
| Dan Marjanovich | Head Driver |
| Stéphanie Weber Biron | Camera Trainee |
| John Sztejnmiler | Generator Operator |
| Sharon Irving | Truck Costumer |
| Erik Holmberg | Production Executive |
| Aric Dupere | Extras Casting Coordinator |
| Marcelo Lago | ADR Recordist |
| Sam Gainer | Assistant Production Coordinator |
| Mike Manzato | Key Set Production Assistant |
| James Kearns | Writer |
| Francine Francis-Lee | Hairstylist |
| Carl Fullerton | Makeup Artist |
| Maureen Mestan | Hairstylist |
| Allison Mondesir | Hairstylist |
| Edelgard K. Pfluegl | Makeup Artist |
| Peter Horn | Assistant Production Manager |
| Avram Butch Kaplan | Unit Production Manager |
| Gavin Biedler | Assistant Director Trainee |
| Darrin Brown | Second Second Assistant Director |
| Richard S. Lederer | First Assistant Director |
| Traci M. Lewis | First Assistant Director |
| Janet Zdyb | Second Second Assistant Director |
| Dominic Chenier | Graphic Designer |
| Michael Hyde | Head Carpenter |
| Andy Bely | Props |
| Gordon Becker | Sculptor |
| Norman Kelner | Standby Painter |
| Dennis Kirkham | Set Dresser |
| Michael J. Meade | Property Buyer |
| John Morrison | On Set Dresser |
| Jae Pak | Assistant Art Director |
| Michele Perkovich | Assistant Art Director |
| Kim Steede | On Set Dresser |
| Craig S. Jaeger | Sound Effects Editor |
| Tony Lamberti | Sound Effects Designer |
| Perry Robertson | Sound Effects Editor |
| Katrina Siegmund | Sound Assistant |
| David Stanke | Sound Assistant |
| Daniel Godin | Special Effects |
| Emile Godin | Special Effects |
| Kaz Kobielski | Special Effects Supervisor |
| Matt Birman | Stunts |
| John Dodds | Stunts |
| Lyle W. Edge | Stunts |
| Jim Finkbeiner | Stunts |
| Reg Glass | Stunts |
| Tom Glass | Stunt Coordinator |
| Layton Morrison | Stunts |
| Rick Parker | Stunts |
| Allan Phillips | Stunts |
| Edward A. Queffelec | Stunts |
| Paul Rutledge | Stunts |
| Monica Staggs | Stunts |
| John Stoneham Jr. | Stunt Coordinator |
| John Stoneham Sr. | Stunts |
| Cathy Sutherland | Stunts |
| Bryan J. Thomas | Stunts |
| Ron Van Hart | Stunts |
| Paul Boucher | Camera Operator |
| Christian Caperaa | Camera Loader |
| Don Caulfield | Electrician |
| Colin Evans | Camera Operator |
| Rick Garbutt | Camera Operator |
| Vince Gordon | Electrician |
| Paul Guenette | First Assistant Camera |
| Pierric Jouvante | Best Boy Electric |
| David Kelly | First Assistant Camera |
| Michael Kohnhorst | Director of Photography |
| Morgan Michael Lewis | Key Grip |
| Cameron MacDonald | Camera Operator |
| Kenneth MacKenzie | Key Grip |
| Alan Millar | Lighting Technician |
| David Moenkhaus | First Assistant Camera |
| Derek Parkes | Grip |
| Gerald Pynn | Grip |
| Bob Rodgers | Electrician |
| Brian Sanders | First Assistant Camera |
| Peter Smith | Camera Operator |
| Kirsta Teague | Second Assistant Camera |
| Robin D. Cook | Casting |
| Donna Dupere | Extras Casting |
| Elizabeth Gray | Casting Associate |
| John Lopez | Casting Associate |
| Frank Perry Rose | Costumer |
| Vanessa Vogel | Assistant Costume Designer |
| Jean Wong | Wardrobe Coordinator |
| Jody Levin | Executive In Charge Of Post Production |
| Brigitte Rabazo | First Assistant Editor |
| Pierre Brunet | Location Manager |
| Peter Horn | Location Manager |
| Dominique Leroutier | Assistant Location Manager |
| Mark Logan | Location Manager |
| Edward York | Assistant Location Manager |
| Richard Ford | Music Editor |
| Brad Warnaar | Orchestrator |
| Aaron Zigman | Orchestrator |
| Percy Budd | Driver |
| Wally Dibacco | Driver |
| Keith Filkins | Transportation Captain |
| Stuart Hughes | Driver |
| Michael K. Jones | Driver |
| Richard Karol | Captain Driver |
| Coleman Robinson | Transportation Coordinator |
| Gerry Savoy | Transportation Captain |
| Richard Savoy | Driver |
| Pat Serpe | Transportation Coordinator |
| William L. Tataryn | Driver |
| Brad Winans | Driver |
| Carolyn Blackwood | Attorney |
| Paule Girardin | Production Coordinator |
| Emily Glatter | Production Supervisor |
| Corwin Hall | Stand In |
| Isabelle Leduc | Production Secretary |
| Robin Mader | Assistant Accountant |
| Enid Rose | Stand In |
| Alex Ross | Stand In |
| Kim Slaughter | Craft Service |
| Dave Tommasini | Pilot |
| Wendy Wilhite Chatley | Studio Teacher |
| Ian Williams | Stand In |
| Zane | Post Production Accountant |
