 | Elliot Page als Juno MacGuff |
 | Michael Cera als Paulie Bleeker |
 | Jennifer Garner als Vanessa Loring |
 | Jason Bateman als Mark Loring |
 | J.K. Simmons als Mac MacGuff |
 | Allison Janney als Bren MacGuff |
 | Olivia Thirlby als Leah |
 | Eileen Pedde als Gerta Rauss |
 | Rainn Wilson als Rollo |
 | Daniel Clark als Steve Rendazo |
 | Darla Fay als Bleeker's Mom |
 | Aman Johal als Vijay |
 | Valerie Tian als Su-Chin |
 | Emily Perkins als Punk Receptionist |
 | Kaaren de Zilva als Ultrasound Technician |
 | Steven Christopher Parker als Guy Lab Partner |
 | Candice King als Amanda, Girl Lab Partner |
| Sierra Pitkin als Liberty Bell |
 | Cut Chemist als Chemistry Teacher |
 | Eve Harlow als Tough Girl |
 | Kirsten Alter als Nurse |
 | Emily Tennant als Pretty-to-Goth Girl |
| Ashley Whillans als Katrina De Voort |
 | Jeff Witzke als Track Announcer |
| Colin McSween als Keith |
| Peggy Logan als Sex Ed Teacher |
 | Cameron Bright als RPG Nerd |
| Joy Galmut als Delivery Room Doctor |
| Wendy Russell als Vanessa's Friend #1 |
 | Robyn Ross als Vanessa's Friend #2 |
| Brad Van Arragon | Producer |
| Daniel Dubiecki | Executive Producer |
| Diablo Cody | Screenplay |
| Mason Novick | Producer |
| Kelli Konop | Producer |
| Steve Saklad | Production Design |
| Joseph Drake | Executive Producer |
| Kara Lipson | Casting |
| Russell Smith | Producer |
| Eric Steelberg | Director of Photography |
| John Malkovich | Producer |
| Kimya Dawson | Songs |
| Lianne Halfon | Producer |
| Nathan Kahane | Executive Producer |
| Dana E. Glauberman | Editor |
| Jim Miller | Producer |
| Monique Prudhomme | Costume Design |
| Jason Reitman | Director |
| Mindy Marin | Casting |
| Peter Afterman | Music Supervisor |
| Margaret Yen | Music Supervisor |
| Mateo Messina | Original Music Composer |
| Nick South | Music Editor |
| Doane Gregory | Still Photographer |
| Sherry Linder-Gygli | Key Hair Stylist |
| Ken S. Polk | Sound Re-Recording Mixer |
| Trevor Westerhoff | Production Coordinator |
| Shane Vieau | Set Decoration |
| Scott Sanders | Sound Re-Recording Mixer |
| Christine Coutts | Assistant Costume Designer |
| Stephanie Rossel | Script Supervisor |
| Scott J. Ateah | Stunt Coordinator |
| J. Stanley Johnston | Sound Re-Recording Mixer |
| Stewart Whelan | First Assistant Camera |
| Paul Lavigne | Costume Supervisor |
| Sandy Cooper | Makeup Artist |
| Richard Dwan Jr. | Sound Editor |
| Monica Huppert | Makeup Artist |
| Paul Arthur Hartman | Set Dresser |
| Christopher Wishart | Set Dresser |
| Michael Mayo | Rigging Gaffer |
| Scott Delaplace | Transportation Captain |
| Rickley W. Dumm | Sound Editor |
| Nick Neutra | Foley |
| Jason Blumenfeld | First Assistant Director |
| Robert A. Pandini | Hairstylist |
| Sigrid Spade | Set Dresser |
| Kevin Tomecek | Carpenter |
| Josephine Bleuer | Greensman |
| Doug Currie | Painter |
| Sergio Lavilla | Set Dresser |
| John Sleep | Special Effects Supervisor |
| Bryan Korenberg | Property Master |
| John Dekker | Chief Lighting Technician |
| Clif Kosterman | Transportation Coordinator |
| Perry Robertson | Supervising Sound Editor |
| Barney Cabral | Supervising ADR Editor |
| Michael Jovanovski | Set Dresser |
| John Beatty | Construction Coordinator |
| Lori West | Art Department Coordinator |
| Tony Wyman | Boom Operator |
| Michael Diner | Art Direction |
| Michael Church | Set Dresser |
| Scott Sanders | Sound Designer |
| Dave Askey | Key Grip |
| Clay Rawlins | First Assistant Editor |
| Catherine Schroer | Art Direction |
| Randy A. Jablonka | Lighting Technician |
| Victoria Down | Key Makeup Artist |
| John Clothier | Camera Operator |
| Neil Robertson | Location Manager |
| Michael Kreple | Foley |
| Marty Coady | Best Boy Grip |
| Patrick Hogue | Second Assistant Camera |
| David Kershaw | Dolly Grip |
| Ian R. C. Levine | Second Assistant "B" Camera |
| David Lourie | First Assistant "B" Camera |
| Dean Morin | Second Assistant Camera |
| Sheryl Rhodes | Assistant Production Coordinator |
