 | Queen Latifah als Leslie Wright |
 | Common als Scott McKnight |
 | Paula Patton als Morgan Alexander |
 | James Pickens Jr. als Lloyd Wright |
 | Phylicia Rashād als Ella McKnight |
 | Pam Grier als Janice Wright |
 | Laz Alonso als Mark Matthews |
 | Mehcad Brooks als Angelo Bembre |
 | Michael Landes als Nelson Kaspian |
 | Lindsay Michelle Nader als Morgan's Friend |
 | Peter Hermann als Dr. Taylor |
| Kim Strother als Bella Goldsmith |
| Leo Allen als Paul |
 | Richard D'Alessandro als Chauffeur |
 | Brely Evans als Sabrina |
 | Rupak Ginn als Raj |
 | Paolo Montalbán als Sommelier |
 | Dwyane Wade als Self |
 | Dwight Howard als Self |
 | Kenny Smith als Self |
 | Jalen Rose als Self |
 | Stuart Scott als Self |
| Rajon Rondo als Self |
| Elton Brand als Self |
| Marv Albert als Self |
 | John Legend als Self |
| Sanaa Hamri | Director |
| Debra Martin Chase | Producer |
| Shakim Compere | Producer |
| Avy Kaufman | Casting |
| Melissa Kent | Editor |
| Robert Pyzocha | Art Direction |
| Queen Latifah | Producer |
| Susan Kaufmann | Set Decoration |
| Amy Cohn | Unit Publicist |
| Terry Stacey | Director of Photography |
| Nicholas Lundy | Production Design |
| Ai-Ling Lee | Sound Designer |
| J. Stanley Johnston | Sound Re-Recording Mixer |
| Josh Blakeslee | First Assistant Camera |
| David J. Thompson | Steadicam Operator |
| Julia Michels | Music Supervisor |
| Marjorie Durand | Makeup Department Head |
| Christopher S. Aud | Supervising Sound Editor |
| John Coots | Best Boy Electric |
| Christopher Barrick | Sound Recordist |
| Shayna Brown | Sound Re-Recording Mixer |
| Seth Tallman | Boom Operator |
| Sam Hutchins | Location Manager |
| Daisy Curbeon | Hair Department Head |
| Sabrina Wright-Gilliar | Property Master |
| Paul Stemmer | Visual Effects Editor |
| George Bianchini | Steadicam Operator |
| David Lee | Still Photographer |
| Amy Andrews | Costume Supervisor |
| Trudy Yee | First Assistant Editor |
| Taurance F. Williams | Key Hair Stylist |
| Terry Rodman | Supervising Sound Editor |
| Gregory H. Watkins | Sound Re-Recording Mixer |
| Jennifer Barak | Music Editor |
| Anita Sum | Production Supervisor |
| Yoshi Sonoda | Lighting Technician |
| Sean Garrett Fogel | Production Supervisor |
| Danny S. Kim | Visual Effects Supervisor |
| Robert Kummert | Dolly Grip |
| Christo Morse | First Assistant Director |
| Ken Shibata | Gaffer |
| Monica Ruiz-Ziegler | Costume Supervisor |
| Gary Martone | Key Grip |
| Migs Rustia | Visual Effects Editor |
| Oliver Cary | Camera Operator |
| David C. Robinson | Costume Designer |
| Wendy Melvoin | Original Music Composer |
| Lisa Coleman | Original Music Composer |
| M. Blair Breard | Co-Producer |
| Gaylyn Fraiche | Co-Producer |
| Jarrod Moses | Co-Producer |
| Michael Elliot | Screenplay |
