 | Angelina Jolie als Lara Croft |
 | Gerard Butler als Terry Sheridan |
 | Ciarán Hinds als Jonathan Reiss |
 | Chris Barrie als Hillary |
 | Noah Taylor als Bryce |
 | Djimon Hounsou als Kosa |
 | Til Schweiger als Sean |
 | Simon Yam als Chen Lo |
 | Terence Yin als Xien |
 | Daniel Caltagirone als Nicholas Petraki |
 | Fabiano Martell als Jimmy Petraki |
 | Jonny Coyne als Gus Petraki |
 | Robert Cavanah als MI6 Agent Stevens |
 | Ronan Vibert als MI6 Agent Calloway |
| Lenny Juma als Village Leader |
| Raymond Ofula als Village Leader |
| Hezron Ajuala als Village Leader |
| Alfred Kalipso als Tribesman |
| Vincent Mbaya als Tribesman |
| Ace Yonamine als Shay Ling Giant |
 | Robert Atiko als Armin Kal |
| Shirley Chantrell als Shu Mei |
| Sang Lui als Shay Ling Messenger |
 | Richard Ridings als Mr. Monza |
 | Elizabeth Seal als Buyer |
| Hajaz Akram als Buyer |
 | Daryl Kwan als Buyer |
 | Richard Ng als Buyer |
| David Karshaw als Buyer |
 | Marem Hassler als Air Stewardess |
 | Kate Loustau als Air Stewardess |
 | Ralf Beck als Sean's Man |
 | Tom Wu als Sean's Man |
 | Gerald Kyd als Sean's Man |
| Mark Sung als Taipei Father |
| Loan Tran als Taipei Mother |
 | Charlotte Nguyen als Taipei Girl |
| Vincent Poon als Taipei Boy |
 | Tom Yang als Reiss' Guard |
 | Jamie Cho als Reiss' Guard |
 | Khan Bonfils als Reiss' Guard |
| Jose Cuenco Jr. als Reiss' Guard |
 | Andrew Joshi als Reiss' Guard |
 | Mark Hampton als Reiss' Guard |
| Michael Wagg als Lead Tech |
| Martin Glyn Murray als Submarine Medic |
 | Graham McTavish als Submarine Captain |
| Sam Arnold als Businessman - Craig (uncredited) |
| David Kershaw als Ben Lomas |
| Alan Silvestri | Original Music Composer |
| Michael Kahn | Editor |
| Philip Lee | Line Producer |
| Lawrence Gordon | Producer |
| John Hubbard | Casting |
| Steven E. de Souza | Story |
| Lloyd Levin | Producer |
| Jan de Bont | Director |
| Dan Hubbard | Casting |
| David Tattersall | Director of Photography |
| David Tattersall | Cinematography |
| James V. Hart | Story |
| Steve Boeddeker | Supervising Sound Editor |
| Lindy Hemming | Costume Designer |
| John Fenner | Art Direction |
| Dennis Bosher | Art Direction |
| Tim Lewis | Unit Manager |
| Chris Clarke | Props |
| Kirk M. Petruccelli | Production Designer |
| Sonja Klaus | Set Decoration |
| Dean Georgaris | Screenplay |
| Frank Walsh | Art Direction |
| Peter Afterman | Music Supervisor |
| Louis A. Stroller | Co-Producer |
| Amy Gilliam | Assistant Director |
| Colin Jamison | Hairstylist |
| Lisa Tomblin | Hairstylist |
| Chen On Chu | Production Manager |
| Michael Solinger | Post Production Supervisor |
| Simon Crane | Stunt Coordinator |
| Simon Crane | Second Unit Director |
| Paul Kirby | Art Direction |
| Neal Callow | Draughtsman |
| Jeremy Heath-Smith | Executive Producer |
| Chris Corbould | Special Effects Supervisor |
| Silver Cheung | Art Direction |
| Matthew Tang | First Assistant Director |
| Bob Nyanja | Third Assistant Director |
| Janeen Schreyer | Makeup Designer |
| Tony Rimwah | Third Assistant Director |
| Ravi Bansal | Conceptual Illustrator |
| Dimitris Birbilis | Second Assistant Director |
| Peter Heslop | Unit Production Manager |
| Anthony Caron-Delion | Assistant Art Director |
| Guy Bradley | Draughtsman |
| Thomas Chow Wai-Kwan | First Assistant Director |
| Chris Brock | Production Manager |
| Jeremy Johns | Production Manager |
| Johnny Wang Yin-Ming | Production Supervisor |
| Belinda Parish | Makeup Artist |
| Shelly Clippard | Associate Producer |
| Neil Morrill | Sculptor |
| Frances Hannon | Makeup Department Head |
| Terry Bamber | Production Manager |
| Holly Goline | Associate Producer |
| Dominic Ackland-Snow | Supervising Carpenter |
| Erica Bensly | Production Manager |
| Steven Begg | Visual Effects Supervisor |
| Suzanne Belcher | Assistant Makeup Artist |
| John C. Hill | Art Direction |
| Jenny Panoutsopoulos | Production Manager |
| Jo McLaren | Stunts |
| Cliff Lanning | First Assistant Director |
| Terry Madden | First Assistant Director |
| Jan Jamison | Hairstylist |
| Toby Hefferman | Second Assistant Director |
| Andrew David Clark | Graphic Designer |
| Jacob Peratrovich | Assistant Unit Manager |
| Rob Burgess | Third Assistant Director |
| Martin Krauka | Second Second Assistant Director |
| Belinda Hodgson | Makeup Artist |
| Adam Brockbank | Conceptual Illustrator |
| Richard Glass | Contact Lens Technician |
| Matthew Sharp | Second Assistant Director |
| Jemma Scott-Knox-Gore | Contact Lens Technician |
| Tracey Lee | Makeup Artist |
| Pierros Andrakakos | Second Second Assistant Director |
| Darlene Forrester | Hairdresser |
| John Slattery | Compositor |
| Terence Madden | Third Assistant Director |
| Mike Britton | Assistant Set Decoration |
| Rob Bliss | Conceptual Illustrator |
| Iain Lawrence | Assistant Director |
| Ben Lanning | Third Assistant Director |
| Rob Bean | Sculptor |
| Christopher Arnold | Set Dresser |
| Christopher Arnold | Props |
| Shaunna Harrison | Makeup Artist |
| Pawel Araskiewicz | Production Assistant |
| Cindy Rodkin | Production Supervisor |
| Josephine Chan | Second Assistant Director |
| Wai Pun Chan | Second Assistant Director |
| Barbara Efthymiou Harris | Third Assistant Director |
| Okongo Mbanda | Third Assistant Director |
| Sin Ka-Leung | Second Second Assistant Director |
| Andrew Barnden | Storyboard Artist |
| Mark Buck | Other |
| Paul Carling | Conceptual Illustrator |
| Mick Chubbock | Other |
| John Hughes | Sound |
