 | Mel Gibson als Martin Riggs |
 | Danny Glover als Roger Murtaugh |
 | Joe Pesci als Leo Getz |
 | Rene Russo als Lorna Cole |
 | Chris Rock als Det.Lee Butters |
 | Jet Li als Wah Sing Ku |
 | Darlene Love als Trish Murtaugh |
 | Traci Wolfe als Rianne Murtaugh |
 | Kim Chan als Benny Chan |
 | Steve Kahan als Captain Ed Murphy |
 | Damon Hines als Nick Murtaugh |
 | Ebonie Smith als Carrie Murtaugh |
 | Michael Chow als Benny's Assistant |
 | Danny Arroyo als Gomez |
 | Elizabeth Sung als Hong's Wife |
 | Bob Jennings als Sheriff #1 |
| Jeanne Chinn als Ping's Mother |
 | Conan Lee als Four Father Michael Sing Ku |
 | Mary Ellen Trainor als Dr. Stephanie Woods |
 | Jessica Jann als Little Girl |
 | Eddy Ko als Hong |
 | Al Leong als Wah Sing Ku Triad Member |
 | Danny Wynands als Flamethrower Villain |
 | Jack Kehler als State Department Man |
 | Richard Riehle als INS Agent |
| Tony Keyes als Ng's Partner |
 | Roger Yuan als Chu |
 | Jeff Imada als Thug |
 | Simon Rhee als Thug |
| Zu-Wu Qian als Uncle Chung |
 | Raymond Ma als Dr. Cheng |
 | Paul Tuerpe als Helicopter Co-Pilot |
 | James Lew als Freighter's Captain |
| James Wing Woo als Four Father James Wing Chow |
| Raymond Moy als Four Father #3 |
 | François Chau als Four Father Li Lum Chung |
 | Stephen Liska als Detective |
 | Roland Kickinger als Detective |
 | Benjamin King als Detective |
 | Al Sapienza als Detective |
 | Jamie Donovan als Detective |
 | Marian Collier als Maternity Worker |
 | Barret Swatek als Nurse |
| Sarah Sullivan als News Reporter |
 | Greg Bronson als CHP Officer (uncredited) |
 | Ray Chang als Ping's Father |
 | Dana Lee als General |
 | George Cheung als Fan |
 | Philip Tan als Waiter |
| Shawn Michaels als Detective |
 | Al Goto als General's Men (uncredited) |
 | Calvin Jung als Detective Ng |
| Mark A. Mangini | Supervising Sound Editor |
| Richard L. Anderson | Sound Effects Editor |
| Joel Silver | Producer |
| Shane Black | Characters |
| Eric Strand | Editor |
| Dallas Puett | Editor |
| Eric Clapton | Original Music Composer |
| Marion Dougherty | Casting |
| Tim Gilbert | Stunts |
| Spencer Franklin | Associate Producer |
| Steve Perry | Executive Producer |
| Frank J. Urioste | Editor |
| Richard Donner | Director |
| Richard Donner | Producer |
| J. Michael Riva | Production Design |
| Michael Kamen | Original Music Composer |
| Michael Kamen | Conductor |
| Buddy Joe Hooker | Stunts |
| Zigmund Gron | Music Editor |
| Bruce Paul Barbour | Stunts |
| R. Anthony Brown | Unit Production Manager |
| Conrad E. Palmisano | Stunt Coordinator |
| Conrad E. Palmisano | Second Unit Director |
| Ezra Dweck | Foley Editor |
| David Sanborn | Original Music Composer |
| Channing Gibson | Screenplay |
| Andrzej Bartkowiak | Director of Photography |
| Kevin Stitt | Editor |
| Lauri Gaffin | Set Decoration |
| David F. Klassen | Art Direction |
| Richard F. Mays | Art Direction |
| Ha Nguyen | Costume Design |
| Tony Brubaker | Stunt Double |
| Mic Rodgers | Second Unit Director |
| Miles Millar | Story |
| Alfred Gough | Story |
| Jonathan Lemkin | Story |
| Chris Boardman | Orchestrator |
| Jim Van Wyck | Executive Producer |
| Henry Kingi | Stunts |
| Dan Cracchiolo | Co-Producer |
| Marcus Miller | Additional Music |
| Thomas Rosales Jr. | Stunts |
| Jennifer Caputo | Stunts |
| William C. Carruth | ADR Editor |
| Steve Adcock | Additional Camera |
| Marc Baird | Production Illustrator |
| Louis Farah | Set Medic |
| Jerome Butler | Dialect Coach |
| Wendy Riva | Assistant Art Director |
| Jimmy N. Roberts | Stunts |
| Huan-Chiu Ku | Martial Arts Choreographer |
| Troy Porter | ADR Mixer |
| Erik Cord | Stunts |
| Gary McLarty | Stunts |
| Troy Brown | Stunt Double |
| Ronnie Rondell Jr. | Stunts |
| Jeff Imada | Stunts |
| John Meier | Stunts |
| Geoff Johns | Co-Producer |
| J. Mills Goodloe | Co-Producer |
| John M. Woodward | Transportation Coordinator |
| Billy D. Lucas | Stunts |
| Charisse Cardenas | Set Designer |
| Christopher Blauvelt | Second Assistant Camera |
| Ilyse A. Reutlinger | Post Production Supervisor |
| Ilyse A. Reutlinger | Associate Producer |
| Baylis Glascock | Assistant Sound Editor |
| Mark Kenna | Dolby Consultant |
| Charlene Amateau | Set Costumer |
| Kimberly Guenther Durkin | Costume Supervisor |
| Gregg Rudloff | Sound Re-Recording Mixer |
| Lance Gilbert | Stunt Double |
| Jennifer Gwartz | Associate Producer |
| Avram D. Gold | Supervising Dialogue Editor |
| Marshall Winn | ADR Editor |
| Susan Dudeck | Dialogue Editor |
| Andrew Cooper | Still Photographer |
| Dan Levitan | Compositing Supervisor |
| Laura Gary | Studio Teachers |
| Pete Romano | Underwater Camera |
| Hans Bjerno | Aerial Director of Photography |
| Steven J. Winslow | Camera Technician |
| Andrew Lipschultz | Unit Publicist |
| Charlene Johnson | Key Hair Stylist |
| Erik L. Nelson | Property Master |
| Ray De La Motte | Camera Operator |
| Michael L. Fink | Visual Effects Supervisor |
| Cheryl Wheeler Duncan | Stunt Double |
| Gregory J. Barnett | Stunts |
| James Simcik | Supervising ADR Editor |
| Carolyn Tapp | Foley Recordist |
| Dale E. Grahn | Color Timer |
| Michael Haro | Location Manager |
| Martin Glover | Video Assist Operator |
| Walt Hadfield | Construction Coordinator |
| John Pospisil | Sound Designer |
| Cristin Pescosolido | Digital Compositors |
| David Taritero | Visual Effects Producer |
| Jill Brown | Stunts |
| Christopher Amy | Assistant Property Master |
| Lisa Deveaux | Makeup Artist |
| David Fencl | Armorer |
| Kareen Boursier | Hairstylist |
| Bill 'Kauhane' Hoyt | Standby Painter |
| Bobby Brown | First Assistant Camera |
| Richard Hartley | Rigging Gaffer |
| Tim Cooney | Production Sound Mixer |
| Thomas S. Dickson | Projection |
| Frank Roughan | Transportation Captain |
| James B. Crawford | Chief Lighting Technician |
| Nico Bally | Dolly Grip |
| Scott Kidner | Lighting Technician |
| Bill Brummond | Steadicam Operator |
| Richard Castro | Special Effects Assistant |
| Carlo Basail | Greensman |
| Troy Gilbert | Stunts |
| Jeff Hay | Set Dressing Artist |
| Douglas Wright | Casting Associate |
| Todd Bassman | Boom Operator |
| Michael J. Coo | Key Grip |
| Lou Kleinman | Sound Effects Editor |
| Peter Roderick | Carpenter |
| Mo Henry | Negative Cutter |
| Robert Ikeda | Grip |
| Cory Fleming | Utility Stunts |
| Jason S. Gondek | Accountant |
| James F. Walker | Construction Foreman |
| Ernest H. Lauterio | Craft Service |
| Gil Amaral | Driver |
| Jacobus Marcus | Camera Loader |
| Jon G. Belyeu | Special Effects Coordinator |
| J. Tom Archuleta | First Assistant Director |
| Tasso Bravos | Best Boy Electric |
| Christian J. Killingsworth | Electrician |
| Robert J. Reilly | Rigging Grip |
| Thomas A. Davila | Production Accountant |
| Bill Maher | Visual Effects Coordinator |
| Stephen McLaughlin | Music Score Producer |
| Eric Gotthelf | Foley Mixer |
| Rick Sawaya | Stunt Driver |
| Annie Ellis | Stunts |
| Josephine Nericcio | Assistant Dialogue Editor |
| Tom von Badinski | Special Effects Technician |
| Jonathan Malden | Colorist |
| Stanley L. Gonsales | Assistant Chief Lighting Technician |
| Chris Bangma | Assistant Camera |
| David Ascher | Second Second Assistant Director |
| Geoff Harding | Assistant Location Manager |
| Cynthia Neber | Executive Assistant |
| Jodie Thomas | Production Assistant |
| Lisa Matsukawa | Production Secretary |
| Art Fransen | Technical Advisor |
| Patricia M. Peters | Stunts |
