 | Mandy Moore als Ava |
 | Kellan Lutz als Charlie |
 | James Brolin als Bradley |
 | Jane Seymour als Betty |
 | Jessica Szohr als Shelby |
 | Michael Weston als Gerber |
 | Marta Żmuda-Trzebiatowska als Kasia |
 | Richard Alan Reid als Ian |
 | Christopher Lloyd als Dr. George |
 | Alexis Denisof als Lloyd |
 | Alyson Hannigan als Courtney |
 | Colleen Camp als Ethel |
 | Julia Roberts als Ava's Therapist (voice) |
 | Andrew Keegan als Jeremiah |
 | Gabrielle Shuff als Adrianna |
 | Autumn Federici als Jessica |
 | Joe Chrest |
| Dermot Mulroney | Director |
| Anouska Chydzik | Screenplay |
| Patricia DiGiacomo | Set Decoration |
| Caprice Crane | Writer |
| Michelle Chydzik Sowa | Producer |
| Blake Neely | Music |
| Óttar Guðnason | Director of Photography |
| Heather Persons | Editor |
| Nancy Nayor | Casting |
| Carlos A. Menéndez | Production Design |
| Chuck Bludsworth | Art Direction |
| Monique Champagne | Art Direction |
| Gail Briant | Set Decoration |
| Leonard R. Spears | Set Decoration |
| Antoinette Messam | Costume Design |
| Margeaux Fox | Hairstylist |
| Sherri Hamilton | Hairstylist |
| Steve Artmont | Makeup Department Head |
| Nicole Artmont | Makeup Artist |
| Krystal Kershaw | Makeup Artist |
| Remi Savva | Makeup Artist |
| Steve Gehrke | Script Supervisor |
| Christopher Brooks | Music Editor |
| Paula Truman | Costume Supervisor |
| Conan Castro Jr. | Costume Supervisor |
| Annette Farnsworth | Set Costumer |
| Michael Arata | Executive Producer |
| Julia Blackman | Executive Producer |
| Jerry Daigle | Executive Producer |
| Stephen Hays | Executive Producer |
| Stefan Jacobs | Executive Producer |
| Daniel March | Executive Producer |
| Gary Raskin | Executive Producer |
| Nathalie Marciano | Executive Producer |
| Larry Blake | Sound Re-Recording Mixer |
| Larry Blake | Supervising Sound Editor |
