 | Jacob Tremblay als Luca Paguro (voice) |
 | Jack Dylan Grazer als Alberto Scorfano (voice) |
 | Emma Berman als Giulia Marcovaldo (voice) |
 | Saverio Raimondo als Ercole Visconti (voice) |
 | Maya Rudolph als Daniela Paguro (voice) |
 | Marco Barricelli als Massimo Marcovaldo (voice) |
 | Jim Gaffigan als Lorenzo Paguro (voice) |
 | Peter Sohn als Ciccio (voice) |
 | Lorenzo Crisci als Guido (voice) |
 | Marina Massironi als Signora Marsigliese (voice) |
 | Gino La Monica als Tomasso (Old Fisherman) (voice) |
 | Sandy Martin als Grandma Paguro (voice) |
 | Giacomo Gianniotti als Giacomo (Young Fisherman) (voice) |
 | Elisa Gabrielli als Concetta Aragosta (voice) |
 | Mimi Maynard als Pinuccia Aragosta (voice) |
 | Sacha Baron Cohen als Uncle Ugo (voice) |
 | Francesca Fanti als Maggiore (Cop) (voice) |
 | Jonathan Nichols als Priest (voice) |
 | Enrico Casarosa als Card Player / Angry Fisherman (voice) |
 | Jim Pirri als Mr. Branzino (voice) |
| Arturo Sorino als Additional Voices (voice) |
| Andrea Warren | Producer |
| Enrico Casarosa | Director |
| Pete Docter | Executive Producer |
| Dan Romer | Original Music Composer |
| Natalie Lyon | Casting |
| Kevin Reher | Casting |
| Niketa Roman | Post-Production Manager |
| Nicolle Castro | Storyboard Artist |
| Justin Doyle | Sound Effects Editor |
| Pascal Garneau | Sound Effects Editor |
| Chris Scarabosio | Sound Re-Recording Mixer |
| Chris Scarabosio | Sound Designer |
| Chris Scarabosio | Supervising Sound Editor |
| Simon Christen | Animation |
| Scott Clark | Animation |
| Youri Dekker | Animation |
| Brandon Kern | Animation |
| Tarun Lak | Animation |
| Aviv Mano | Animation |
| Aaron McGriff | Animation |
| Nicole Ridgwell | Animation |
| Daniel A. Rodriguez | Animation |
| Sikand Srinivas | Animation |
| David Torres | Animation |
| Luis Carlos Uribe | Animation |
| Bruna Berford | Fix Animator |
| Yon Hui Lee | Storyboard Artist |
| Kirsten Yamaguchi | Fix Animator |
| Terri Douglas | ADR Voice Casting |
| Jessica Katz | Editorial Coordinator |
| Paloma Rodriguez | Assistant Editor |
| Ennio Morricone | In Memory Of |
| Mark Graham | Conductor |
| Kelly Bonbright | Script Supervisor |
| Rayna Helgens | Script Supervisor |
| Kristian Kobe | Publicist |
| Amy L. Allen | Set Dressing Artist |
| Jennifer Leigh King | Lighting Artist |
| Daniela Strijleva | Production Design |
| David Juan Bianchi | Director of Photography |
| Kim White | Director of Photography |
| Michael Venturini | Animation Supervisor |
| David Ryu | Visual Effects Supervisor |
| Catherine Apple | Editor |
| Jason Hudak | Editor |
| Peter Sohn | Executive Producer |
| Kiri Hart | Executive Producer |
| Kate Hansen-Birnbaum | Casting Associate |
| Enrico Casarosa | Story |
| Jesse Andrews | Story |
| Simon Stephenson | Story |
| Sungyeon Joh | Lighting Artist |
| Seong-Young Kim | Layout |
| Julie Lynn | Story Consultant |
| Randall Green | Story Consultant |
| Jesse Andrews | Screenplay |
| Mike Jones | Screenplay |
| Daniela Kriston | Researcher |
| JD Ohlerking | Finance |
| Jesus Martinez | Dailies Manager |
| Kenny Pickett | Sound |
| John Hoffman | Story Supervisor |
