 | Dylan O'Brien als Thomas |
 | Kaya Scodelario als Teresa Agnes |
 | Thomas Brodie-Sangster als Newt |
 | Ki Hong Lee als Minho |
 | Rosa Salazar als Brenda |
 | Giancarlo Esposito als Jorge |
 | Will Poulter als Gally |
 | Jacob Lofland als Aris Jones |
 | Patricia Clarkson als Ava Paige |
 | Aidan Gillen als Janson |
 | Walton Goggins als Lawrence |
 | Dexter Darden als Frypan |
 | Katherine McNamara als Sonya |
 | Nathalie Emmanuel als Harriet |
 | Barry Pepper als Vince |
 | Dylan Smith als Jasper |
 | Jake Curran als WCKD Lieutenant |
 | Dylan Kriek als Co Conductor |
 | Scot Cooper als Station Chief |
| Kazi Maubert als Immune Child |
 | Bart Fouche als Engineer |
 | Greg Kriek als Co-Conductor |
 | Paul du Toit als Berg Pilot |
 | Liza Scholtz als Nurse |
| Shai Lun Choo als Little Girl |
| Fiona Ramsay als Board Member |
 | Paul Hampshire als Soldier |
| Nathan Barris als Soldier |
| Drikus Volschenk als Team Leader |
 | Clayton Evertson als WCKD Operator |
 | Emily Child als Infected Woman |
| Dale Jackson als Holding Area Guard |
| Armando De Leca als WCKD Guard |
 | Paul Lazenby als Guard (uncredited) |
 | Parm Soor als Board Member (uncredited) |
| Nicole Connelly | Special Effects |
| Wes Ball | Director |
| T.S. Nowlin | Screenplay |
| James Dashner | Novel |
| Wyck Godfrey | Producer |
| Ellen Goldsmith-Vein | Producer |
| John Ottman | Sound Mixer |
| Blair Clark | Visual Effects Supervisor |
| Seth Kenlon | Visual Effects |
| Lee Stollman | Producer |
| Dan Zimmerman | Editor |
| Denise Chamian | Casting |
| Daniel T. Dorrance | Production Design |
| Andrea Borland | Art Direction |
| Michael Diner | Art Direction |
| Ross Jenkin | Art Direction |
| Grant Van Der Slagt | Art Direction |
| Sanja Milković Hays | Costume Design |
| Lisa Love | Makeup Department Head |
| Nicole Oguchi | Production Supervisor |
| Shannon Courte | Art Department Coordinator |
| John Dale | Construction Coordinator |
| Lisa Godwin | Propmaker |
| Julieta Jiménez | Set Designer |
| Andrew Lee McConnell | Set Designer |
| Gary Young | Sculptor |
| Darren Brisker | Sound Mixer |
| Scott Puckett | Visual Effects Producer |
| Steve Chang | Stunts |
| Shane Daniels | Stunts |
| Paul Lazenby | Stunts |
| Patrick Phan | Stunts |
| Julia Rekaikyna | Stunts |
| Glenn Suter | Stunt Coordinator |
| Rhys Williams | Stunts |
| Scott Kozak | Rigging Grip |
| Sean Oxenbury | Rigging Gaffer |
| Colin Robson | Grip |
| Armand Santos | Best Boy Electric |
| Dean Schwingboth | Grip |
| Beth Day | Casting Associate |
| Liz Ludwitzke | Casting Associate |
| Jessica Lythgoe-Green | Costume Supervisor |
| Nava R. Sadan | Costume Supervisor |
| Irena Stepić | Assistant Costume Designer |
| Logan Breit | Visual Effects Editor |
| Wendy Nomiyama | Assistant Editor |
| Ron Irvine | Transportation Captain |
| David Holm | Transportation Coordinator |
| Carrie O'Bray | Transportation Captain |
| Morgan Brady | Production Coordinator |
| Suze Dunbar | Script Supervisor |
| Joecy Shepherd | Script Supervisor |
| Julieann Snow | Production Accountant |
| Gyula Pados | Director of Photography |
| John Paesano | Original Music Composer |
| Davide Anselmi | Sound Editor |
| Wes Ball | Producer |
| Marty Bowen | Producer |
| Joe Hartwick Jr. | Producer |
| Patrick O'Connor | Art Direction |
| Catherine Palmer | Art Direction |
| Hugo Santiago | Art Direction |
| Moray McGregor | Standby Art Director |
| Christophe Dalberg | Supervising Art Director |
| Gaby Beyers | Art Department Coordinator |
| Jerry Staar | Assistant Property Master |
| Darren Christian | Concept Artist |
| Frederick Mpuuga | Concept Artist |
| Michel Smit | Concept Artist |
| Darek Zabrocki | Concept Artist |
| Raj Rihal | Conceptual Design |
| Stevo Bedford | Conceptual Illustrator |
| Gordon Russell | Construction Foreman |
| Garreth Carikas | Graphic Designer |
| Thomas Dorman | Graphic Designer |
| Rohan Lyal | Head Greensman |
| Carla Jackson | Head Greensman |
| Dean Eilertson | Property Master |
| Kerry van Lillenveld | Property Master |
| Brett Hirson | Set Designer |
| Siobhan Roome | Set Designer |
| Lauren Sevior | Set Dresser |
| Mark Risk | Storyboard Artist |
| Ronald Hersey | Aerial Director of Photography |
| Niall Fraser | Best Boy Electric |
| Samantha Davids | Camera Loader |
| Peter Belcher | Camera Operator |
| Danie du Toit | Camera Operator |
| Alessandro Brambilla | Steadicam Operator |
| Adi Visser | Steadicam Operator |
| Josh Bleibtreu | Second Unit Director of Photography |
| Keith Johnston | Dolly Grip |
| Adrian van As | Dolly Grip |
| dron | Drone Cinematographer |
| Jed Harris | Electrician |
| Moses Makateng | Electrician |
| Alfred Mxathule | Electrician |
| Vincent Ngcobo | Electrician |
| Athi Pokolo | Electrician |
| Berndt Wiese | First Assistant Camera |
| Daniel Bombell | First Assistant "A" Camera |
| Evan Maclachlan | First Assistant "A" Camera |
| E.J. Misisco | First Assistant "B" Camera |
| Adrian Boerlage | First Assistant Camera |
| Oliver Wilter | Gaffer |
| J.P. Ridgway | Key Grip |
| Mark Forster | Key Grip |
| Nick Phillips | Libra Head Technician |
| Keith Saayman | Libra Head Technician |
| Negoita Mihai | Libra Head Technician |
| Marcel Klopper | Libra Head Technician |
| David McIntosh | Rigging Grip |
| Dan Sigobongo | Rigging Grip |
| Johnny Gidcomb | ADR Voice Casting |
| J.P. van der Merwe | Extras Casting |
| Michelle Karavoussanos | Assistant Costume Designer |
| Summer Dietz | Assistant Costume Designer |
| Michanne Kirsten | Costume Assistant |
| Debra Trevino | Costume Assistant |
| Abigail Metcalfe | Costume Supervisor |
| Tamsyn Lee Wilson | Ager/Dyer |
| Natasha Gale | Costumer |
| Laurel Morgan | Costumer |
| Nawaal Hendriks | Costumer |
| Sean Haley | Key Costumer |
| Wendy L. Schilling | Key Costumer |
| Isabel Bloor | Key Costumer |
| Hetta Burger | Wardrobe Supervisor |
| Michael Rostker | 3D Editor |
| Ben Cox | Assistant Editor |
| Greg Hollander | Assistant Editor |
| Alex Oreman | Digital Intermediate |
| Michael Van Fleet | Digital Intermediate |
| Noel Albornoz | Digital Intermediate Editor |
| P.J. Burch | First Assistant Editor |
| Jeff Carson | Music Editor |
| Charles Martin Inouye | Music Editor |
| Paul Jasper | Animal Coordinator |
| Rob Fournier | Armorer |
| Kim Robinson | Continuity |
| Reinier Smit | Script Supervisor |
| Kelsey Wheeler | Pilot |
| Vinca Cox | Script Supervisor |
| Beth Li | Title Designer |
| Michael Umble | Unit Publicist |
| Derek Casari | ADR Engineer |
| David Betancourt | ADR Mixer |
| Garret Farrell | ADR Mixer |
| Kristin Catuogno | ADR Recordist |
| Gavin Coford | Boom Operator |
| Bruce K. Malala | Boom Operator |
| Helen Luttrell | Dialogue Editor |
| John T. Cucci | Foley Artist |
| Dan O'Connell | Foley Artist |
| Roberto Dominguez Alegria | Foley Mixer |
| James Ashwill | Foley Mixer |
| John Guentner | Foley Mixer |
| Davide Anselmi | Production Sound Mixer |
| Lee Gilmore | Sound Designer |
| Tobias Poppe | Sound Designer |
| Ai-Ling Lee | Sound Designer |
| Chris Diebold | Sound Effects Editor |
| Chris Terhune | Sound Effects Editor |
| Tim Gomillion | Sound Recordist |
| Ai-Ling Lee | Sound Re-Recording Mixer |
| Ai-Ling Lee | Supervising Sound Editor |
| Susan Dawes | Supervising Dialogue Editor |
| Andrew Butterfield | Animation |
| Stanislav Dovliashewicz | Animation |
| Jazmin Evans | Animation |
| Alessandro Saponi | CG Supervisor |
| Einar Martinsen | Matte Painter |
| John Walters | Matte Painter |
| Ryan Cronin | Senior Animator |
| Vincent Désilets | Senior Animator |
| Niall Lenihan | Software Engineer |
| Sam Ashford-Rowe | Visual Effects Coordinator |
| Marc Faladeau | Visual Effects Coordinator |
| Amanda Newby | Visual Effects Coordinator |
| Sky Stone | Visual Effects Coordinator |
| Katherine Terzieva | Visual Effects Coordinator |
| Jennifer Ramos | Visual Effects Coordinator |
| Jeffrey J. Marks | Visual Effects Producer |
| Andrew Eick | Visual Effects Producer |
| Martin Wiseman | Visual Effects Producer |
| Matt Sloan | Visual Effects Supervisor |
| R. Christopher White | Visual Effects Supervisor |
| Mike F. Hedayati | Visual Effects Supervisor |
| Daniel Macarin | Visual Effects Supervisor |
| Rachel Hannah Cohen | Visual Effects Production Manager |
| Vasilis Antipas | Visual Effects Technical Director |
| Oliver Ferguson | Visual Effects Technical Director |
| Lorenzo di Bonaventura | Executive Producer |
| Jerry Graham | Animation |
| Ronan Binding | Animation |
| William Booker | Second Unit First Assistant Director |
| Nadia Brand | Second Assistant Director |
| Benjamin Cairns | Third Assistant Director |
| Cameron Hadlow | Third Assistant Director |
| David Klohn | Second Assistant Director |
| Vincent Lascoumes | First Assistant Director |
| Leroy Titus | Second Second Assistant Director |
| Megan Truter | Second Second Assistant Director |
| Tamara Allen | Production Supervisor |
| James Powers | Unit Production Manager |
| Nicola Unsworth | Unit Production Manager |
| Dave Lovano | Stunts |
| Chang Jung-min | VFX Artist |
| Tom Brown | Music Arranger |
| Will Ropp | ADR & Dubbing |
| James Chung | Concept Artist |
