 | Jamie Foxx als Det. Ricardo 'Rico' Tubbs |
 | Colin Farrell als Det. James 'Sonny' Crockett |
 | Gong Li als Isabella |
 | Naomie Harris als Det. Trudy Joplin |
 | John Ortiz als José Yero |
 | Ciarán Hinds als FBI Agent John Fujima |
 | Justin Theroux als Det. Larry Zito |
 | Barry Shabaka Henley als Lt. Martin Castillo |
 | Elizabeth Rodriguez als Det. Gina Calabrese |
 | John Hawkes als Alonzo Stevens |
 | Eddie Marsan als Nicholas |
 | Luis Tosar als Arcángel de Jesús Montoya |
 | Domenick Lombardozzi als Det. Stan Switek |
 | Isaach De Bankolé als Neptune |
 | Tom Towles als Coleman |
 | Mario Ernesto Sánchez als El Tiburon |
 | Frankie J. Allison als Deep-Chested Aryan Brother |
 | Tony Curran als Aryan Brother |
 | Stephan Jones als Dark-Haired Aryan Brother |
 | Rob Larson als Long-Haired Aryan Brother |
 | Don Frye als Long-Haired Aryan Brother |
| Maxim Danilov als Russian FBI Agent |
 | Pasha D. Lychnikoff als Russian FBI Agent |
 | Ana Cristina Oliveira als Female Bartender |
| Everlayn Borges als Miss Cuba |
| Juanita Billue als Miss Jamaica |
| Patrick Michael Buckley als Air Traffic Controller |
 | Marc Macaulay als Air Traffic Supervisor |
 | Mike Pniewski als ER Doctor |
| Vivienne Sendaydiego als ER Doctor |
| Richard Katanga als Haitian Paramilitary Captain |
 | Dexter Fletcher als Haitian Paramilitary |
 | Oleg Taktarov als Russian Security |
| Alexander Rafalski als Isabella's Security |
| Ilan Krigsfeld als Isabella's Russian Bodyguard |
| Juliana Guedes als Isabella's Secretary |
| James Maurice Rowan Jr. als Guy in Double Wide Trailer |
| Deborah Demere als Woman in Double Wide Trailer |
| Abdel Tornes als The Courier |
| Maria Leon als Casino Office Worker |
| Kenny Acevedo als FBI Agent |
| Julia Yarbrough als Self |
| Ryan M. Phillips als Newscaster |
| Amir Aviram als Guy Hitting on Gina |
| Julia Perevedentseva als Blonde Talking to Tubbs |
| Gilbert Quintana als Marine Shed Guard |
| Eboni Nichols als Dancer |
 | Donald Dowd als Nightclub Patron (uncredited) |
| Paul Aldanée als Mansion VIP (uncredited) |
| Alexander Alonso als Yero Security (uncredited) |
 | Jay Amor als Yero Security (uncredited) |
| Ryan Anthony als Club Patron (uncredited) |
| Chris Astoyan als Agent Perry (uncredited) |
 | Ashley Avis als Supermodel (uncredited) |
| Brad Batchelor als Boat Race Fan (uncredited) |
 | Eric Bendross als Night Club Patron (uncredited) |
| Arthur Bergman als Man Waiting in Nightclub Line (uncredited) |
| Robert Berson als Drug Cartel Operator (uncredited) |
 | Tara Cardinal als Club Girl (uncredited) |
| Michelle Chin als Isabella's Mother (uncredited) |
 | Hailey Hansard als Dancer (uncredited) |
| Stephane Kay als Miami Nightclub Doorman (uncredited) |
| Claudine Oriol als Club Patron (uncredited) |
 | Danny Pardo als Salsa Dancer (uncredited) |
| Pablo Patlis als Bartender (uncredited) |
| Nathan Russell als DEA Agent (uncredited) |
| Taso N. Stavrakis als Long-Haired Sniper (uncredited) |
| Lorenzo Toledo als Yero Security (uncredited) |
| Jon Tomlinson als Powerboat Throttleman (uncredited) |
 | Joe Vida als Detective Jones (uncredited) |
 | David Yuzuk als Bodyguard (uncredited) |
| Julia Zgoda als Dancer (uncredited) |
| Pieter Jan Brugge | Producer |
| Paul Rubell | Editor |
| Francine Maisler | Casting |
| John Murphy | Original Music Composer |
| William Goldenberg | Editor |
| Michael Mann | Producer |
| Dion Beebe | Director of Photography |
| Victor Kempster | Production Design |
| Michael Mann | Writer |
| Michael Mann | Director |
| Wayne Morris | Associate Producer |
| Bryan H. Carroll | Co-Producer |
| Gusmano Cesaretti | Co-Producer |
| Anthony Yerkovich | Executive Producer |
| Michael Waxman | Co-Producer |
| Sarah Bradshaw | Associate Producer |
| James W. Tyson | Costume Supervisor |
| Mat Beck | Visual Effects Supervisor |
| Carlos A. Menéndez | Art Direction |
| Jim Erickson | Set Decoration |
| Kim Lee | Visual Effects Producer |
| Fumi Mashimo | Animation Supervisor |
| Frank Connor | Still Photographer |
| Robert Stadd | Visual Effects Supervisor |
| Mark Davison | Camera Operator |
| Pamela Alch | Script Supervisor |
| Jay Kriss | Camera Operator |
| Janty Yates | Costume Design |
| Jayne-Ann Tenggren | Script Supervisor |
| Ronald B. Moore | Visual Effects Producer |
| Alejandra Rosasco | Costume Supervisor |
| Ken Blackwell | Visual Effects Editor |
| John F. Gross | Visual Effects Supervisor |
| Duane Manwiller | Steadicam Operator |
| Gary Jay | Camera Operator |
| Steve Koster | Helicopter Camera |
| Michael Kaplan | Costume Design |
| Seth Reed | Supervising Art Director |
| Del Spiva | Music Editor |
| Steve Durkee | Music Editor |
| Ed Callahan | Sound Effects Editor |
| Kim Secrist | Sound Effects Editor |
| Tom Kramer | Music Editor |
| Victor Iorillo | Sound Effects Editor |
| Steve Nelson | Sound Effects Editor |
| David M. Ronne | Production Sound Mixer |
| Andy Nelson | Sound Re-Recording Mixer |
| David Olson | Music Editor |
| Anna Behlmer | Sound Re-Recording Mixer |
| James T. Hill | Music Editor |
| Vicki Hiatt | Music Supervisor |
| Artie Malesci | Stunt Coordinator |
| Elliott Koretz | Sound Designer |
| Michael Payne | Sound Effects Editor |
| Joe Dorn | ADR Editor |
| Nicholas Korda | ADR Editor |
| Linda Folk | ADR Editor |
| Susan Dudeck | Supervising ADR Editor |
| Steven R. Mathis | Gaffer |
| J. Michael Muro | Second Unit Director of Photography |
| Michele Perrone | Supervising ADR Editor |
| David V. Butler | Supervising Dialogue Editor |
| Thierry J. Couturier | Dialogue Editor |
| Mike Chock | Dialogue Editor |
| Allen Hartz | Dialogue Editor |
| Lucy Coldsnow-Smith | Dialogue Editor |
| Genessa Goldsmith Proctor | Scenic Artist |
| Don Libby | 3D Artist |
| Scott Dale | Utility Stunts |
| François Audouy | Production Illustrator |
| Norene Bini | Dialect Coach |
| Miguel Batista | Electrician |
| J. Steven Latham | First Assistant Camera |
| Melissa Binder | Textile Artist |
| Derek Casari | ADR Engineer |
| Vinson Jae | Standby Painter |
| Frank Fernandez | Set Medic |
| Roberto Ballesteros | Camera Loader |
| James Irvin Gates | Tailor |
| Carol Raskin | Hairstylist |
| Julian Mercado | Painter |
| Mauriece Jacks Jr. | Video Assist Operator |
| Chris Castaldi | Second Second Assistant Director |
| Geoffrey S. Grimsman | Set Designer |
| Hans Bjerno | Aerial Director of Photography |
| Janene Balado | Post Production Assistant |
| Jay Gutierrez | Stand In |
| Miguel Amauris Jimenez | Key Grip |
| Sean Hobin | Additional Second Assistant Director |
| Michael J. Flynn | Greensman |
| Patrick Calabrese | Set Dresser |
| Marc Deschaine | Assistant Sound Editor |
| R. Blaine Currier | Picture Car Coordinator |
| José Lázaro Brañas | Set Production Assistant |
| Stephen Coleman | Orchestrator |
| Selena Evans-Miller | Assistant Makeup Artist |
| Juan Piccininno | Hair Assistant |
| Vera Mitchell | Wig Designer |
| Mauricio Perez Orlando | Unit Manager |
| Sarah Bradshaw | Unit Production Manager |
| Michael Kelem | Aerial Camera |
| Eric Yu | Camera Technician |
| Stephen P. Durante | Leadman |
| Robert Renga | Sound Recordist |
| Federico López | Assistant Production Manager |
| Martin Charles | Graphic Designer |
| Mary Burton | Makeup Department Head |
| Robyn-Alain Feldman | Post Production Supervisor |
| Jonathan Dugas | Rigging Grip |
| Marian Toy | Assistant Costume Designer |
| Keith D. Fisher | Transportation Co-Captain |
| Thell Reed | Armorer |
| Mack McKelvey | Craft Service |
| Ricou Browning Jr. | Marine Coordinator |
| David Fulton | Publicist |
| Shirley Lu | Translator |
| Kasra Farahani | Conceptual Illustrator |
| Ico Abreu | Construction Buyer |
| Bruce Schluter | Title Designer |
| Aran Mann | Assistant Art Director |
| Nikoletta Skarlatos | Makeup Artist |
| Karen Jarnecke | Production Coordinator |
| Bruno Alzaga | Grip |
| Benjamin Gerry | Casting Associate |
| Jack Taggart | Ager/Dyer |
| R. Bruce Steinheimer | Special Effects Supervisor |
| Robert A. Blackburn | Construction Coordinator |
| Kurt Smith | Color Timer |
| Takeo Ogawa | Sound Designer |
| Brett M. Reed | First Assistant Editor |
| Jeff Okabayashi | Second Assistant Director |
| Andrea D'Amico | Executive Visual Effects Producer |
| Marc Wostak | Rigging Gaffer |
| Don Baer | Driver |
| Bryan Wengroff | Visual Effects Coordinator |
| Alexander Alonso | Stunts |
| Rick Chavez | Assistant Property Master |
| Nikoletta Skarlatos | Key Makeup Artist |
| Peter Cordova | Props |
| Tiffany Busche | Costumer |
| Risa Garcia | Set Costumer |
| Cary Weitz | Boom Operator |
| Miguel Ángel Poveda | Production Manager |
| Jeff G. Waxman | Production Supervisor |
| Michael Waxman | First Assistant Director |
| Charles Stewart | Property Master |
| Travis Huffman | Propmaker |
| Cynthia Quan | Production Accountant |
| James Bolt | Additional Sound Re-Recording Mixer |
| Kat Wilson | Art Department Coordinator |
| Clete Cetrone | Construction Foreman |
| Howard Bachrach | Transportation Captain |
| John C. Kruize | Post Production Accountant |
| Chiara Bergonzi | Costume Assistant |
| Greg Zimmerman | ADR Recordist |
| Gustavo Borner | Scoring Mixer |
| Leah Sokolowsky | Location Scout |
| George Doering | Musician |
| Kevin Tiesiera | Best Boy Electric |
| Dawn Y. Line | Key Costumer |
| Fernando Segovia | Special Effects Assistant |
| Erik Curtis | Second Assistant Camera |
| Merry Alderman | Casting Assistant |
| S.R. Conger | Assistant Accountant |
| Susann Belaval | Art Department Production Assistant |
| Cynthia Blaise | Dialogue Coach |
| Rik Panero | I/O Manager |
| Troy N. Wade | Dolly Grip |
| Jim Weidman | Supervising Music Editor |
| Dixiana Rubio | Production Secretary |
| Melissa Herron | Travel Coordinator |
| Bruce Barris | First Assistant Sound Editor |
| T. Rafael Cimino | Technical Advisor |
| Jonás Rodríguez | Sound Assistant |
| Robert Caban | Special Effects Technician |
| Cory Lee | Visual Effects Production Assistant |
| Kevin Hickman | Assistant Editor |
| Tom Udell | Accountant |
| Henry Herrera | Choreographer |
| Pedro M. Guillen | Executive Assistant |
| Jody Beaudin | First Assistant Accountant |
| Alyson Dee Moore | Foley Artist |
| Don Abbatiello | Stunt Driver |
| Timothy Clark | Matte Painter |
| Al Guthery | Pilot |
| Dan Herrera | Unit Medic |
| Paul Tanzillo Jr. | Negative Cutter |
| Sam Restivo | Post Production Coordinator |
| Angie Lee Cobbs | Assistant Production Coordinator |
| Eddie Mariano | Extras Casting Coordinator |
| Tom Rebber | Transportation Coordinator |
| Nick Theodorakis | Digital Imaging Technician |
| Wilson De Souza Lobo | Assistant Location Manager |
| Rebekah Burgess | Researcher |
| Wiley Schott | Camera Production Assistant |
| Stefan Sonnenfeld | Colorist |
| Joel Tokarsky | Payroll Accountant |
| Kathryn Faison | Stunt Double |
| Joe Hathaway | Digital Color Timer |
| Scottpatrick J. Sellitto | Music Consultant |
| Craig Hosking | Aerial Coordinator |
| Rocio De Leon | Extras Casting Assistant |
| Almudena Alcazar | Production Assistant |
| Marilyn Graf | Foley Mixer |
| Barbara Harris | ADR Voice Casting |
| Christine Carr | Digital Intermediate Producer |
| Cristina Christian | Second Assistant Accountant |
| Maria K. Chavez | Location Manager |
| Sean Brown | Assistant Camera |
| Joshua A. Horn | Location Assistant |
| Mark Robben | Digital Compositor |
| Richard Patterson | Digital Supervisor |
| Ellen J. Morris | Second Assistant Production Coordinator |
| Kurt Beckler | Best Boy Grip |
| Stefani Rockwell | Location Coordinator |
| David S. Williams Jr. | Compositing Supervisor |
| Donald Reynolds Jr. | Key Rigging Grip |
| Christopher Gray | Location Casting |
| Mark De Alessandro | Stunt Driver |
| Denise Gallo | Utility Stunts |
| Maria Norman | Executive Assistant |
| Chick Bernhard | Stunt Driver |
| Eric Luling | Set Dresser |
| Anthony Yerkovich | Original Series Creator |
| Amy Lynn Tuttle | Stunt Driver |
