 | Sandra Bullock als Gracie Hart |
 | Regina King als Sam Fuller |
 | Enrique Murciano als Jeff Foreman |
 | William Shatner als Stan Fields |
 | Eileen Brennan als Carol Fields |
 | Ernie Hudson als Harry McDonald |
 | Elisabeth Röhm als Janet McKaren |
 | Nick Offerman als Karl Steele |
 | Abraham Benrubi als Lou Steele |
 | Treat Williams als Walter Collins |
 | Heather Burns als Cheryl Frasier |
 | Diedrich Bader als Joel Meyers |
 | Octavia Spencer als Octavia |
 | Leslie Grossman als Pam |
 | David Proval als Mr. Grant |
 | John DiResta als Agent Clonsky |
 | Audrey Wasilewski als Mother in Bank |
 | Stephen Tobolowsky als Tom Abernathy |
 | Regis Philbin als Regis Philbin |
 | Joy Philbin als Joy Philbin |
 | Dolly Parton als Dolly Parton |
 | Susan Chuang als Agent Tobin |
 | Adam LeFevre als Bartender |
 | Richard DeDomenico als Bar Patron # 2 |
| Cynthia Pepper als Tourist Woman |
 | Megan Cavanagh als Shirley |
 | Brad Grunberg als Elizabeth Taylor Impersonator |
| Larry Edwards als Impersonator |
 | Roxana Ortega als Mrs. Gordon |
 | Todd Sherry als Dolly Parton Impersonator |
 | Max Shippee als Young Man |
 | Christian Vincent als Drag Club Dancer |
 | Emy Coligado als Gate Agent |
 | Marcelo Tubert als Roberto Fenice |
 | Vic Chao als Agent Hills |
| Rachel Iverson als Rachel |
 | Eve Gordon als Housewife # 2 |
| Marjorie Lovett als Bank Customer |
 | Michelle Page als Punk Girl in Bank |
 | Lusia Strus als Janine |
 | William O'Leary als Agent Jenkins |
 | Ayesha Orange als Drag Club Dancer |
| Tim Clark als Man in Crowd |
| Octavia Spencer als Octavia - Bookstore |
| Mary Ann Price als Dolly Parton's Assistant |
| Tracy Elizabeth Blackwell als Venetian Singer #2 |
 | Susan Leslie als Reporter #2a |
 | Larry Edwards als Patti LaBelle Impersonator / Tina Turner Impersonator #2 |
| April Blanchette als Fan Girl |
| Rose Davidson als Hotel Guest |
| Rebecca Engel als Dealer |
| Anna Wendt als Dolly Parton fan |
 | Faith Minton als Housewife #1 |
 | Lloyd Kino als Asian Tourist Husband |
| Molly Gottlieb als Priscilla |
 | Billie Perkins als Tourist (uncredited) |
| Bruce Berman | Executive Producer |
| Nancy Foy | Casting |
| Leslie E. Rollins | Set Decoration |
| Jack Gill | Stunt Coordinator |
| Jack Gill | Second Unit Director |
| Marilyn Graf | Foley Mixer |
| Maher Ahmad | Production Design |
| Deena Appel | Costume Design |
| Robin Beauchesne | Makeup Artist |
| Sandra Bullock | Producer |
| Peter Menzies Jr. | Director of Photography |
| Marc Lawrence | Screenplay |
| Marc Lawrence | Producer |
| Austin Gorg | Assistant Art Director |
| Garth Craven | Editor |
| Andrew Max Cahn | Art Direction |
| John Van Tongeren | Music |
| John Pasquin | Director |
| Mary McLaglen | Producer |
| Mary McLaglen | Unit Production Manager |
| Katie Ford | Screenplay |
| Caryn Lucas | Screenplay |
| Gary Archer | Prosthetics |
| Bryan Belair | Construction Coordinator |
| Peter Zuccarini | Underwater Camera |
| Susan E. Novick | Post Production Supervisor |
| Al Cerullo | Pilot |
| Troy Porter | ADR Mixer |
| David Orr | Color Timer |
| Jeffrey D. Stevens | Set Medic |
| Greg Zimmerman | ADR Recordist |
| Christopher Duskin | Camera Operator |
| Russell Bobbitt | Property Master |
| Richard Ziegler | Music Editor |
| Bruce Stambler | Supervising Sound Editor |
| John Roesch | Foley Artist |
| K.C. Colwell | First Assistant Director |
| Ann Masterson | Key Makeup Artist |
| Lori DeLapp | Costume Supervisor |
| Daniel R. Jennings | Set Designer |
| Kevin E. Carpenter | Sound Re-Recording Mixer |
| David E. Campbell | Sound Re-Recording Mixer |
| John Finklea | Music Editor |
| Anthony Ortiz | Boom Operator |
| Andy Ryan | Chief Lighting Technician |
| Allen Hall | Special Effects Coordinator |
| Gregg Barbanell | Foley Artist |
| Steve Pederson | Sound Re-Recording Mixer |
| Frank Masi | Still Photographer |
| Sharon Cingle | Script Supervisor |
| Paul Curtis | Supervising Sound Editor |
| Bernard Weiser | Sound Effects Editor |
| Alyson Dee Moore | Foley Artist |
| Pete Romano | Underwater Director of Photography |
| Chris Haarhoff | Camera Operator |
| Peter J. Silbermann | Unit Publicist |
| Candice D. Campos | Production Coordinator |
| Kim Santantonio | Hair Department Head |
| Steve Koster | Aerial Director of Photography |
| Greg Steele | ADR Mixer |
| Becky Sullivan | Supervising ADR Editor |
| JoAnn Stafford-Chaney | Key Hair Stylist |
| Jonathan Bobbitt | Leadman |
| Fatima Robinson | Choreographer |
| Steve Nelson | Sound Effects Editor |
| Sean Gowrie | Production Secretary |
| Gregory Lundsgaard | Steadicam Operator |
| Stephen P. Robinson | Sound Effects Editor |
| Ketty Gonzalez | Hairstylist |
| Greg Richman | Art Direction |
| Pamela S. Westmore | Makeup Supervisor |
| Dan Sweetman | Storyboard Artist |
| Randy Bobbitt | Art Department Coordinator |
| John Houlihan | Music Supervisor |
| Paul Aulicino | Sound Effects Editor |
| Ann Foley | Key Costumer |
| Michael Barosky | Sound Mixer |
| Mark Weingarten | Sound Mixer |
| Patrick Cusack | Assistant Sound Editor |
| Ahmed Saker | Set Medic |
| Chris Furia | Production Accountant |
| Craig Comstock | Second Second Assistant Director |
| Mark Swenson | Assistant Production Coordinator |
| Paula Case | Second Assistant Director |
| Lawrence L. Commans | Boom Operator |
| Mo Henry | Negative Cutter |
| Jonathan Klein | Foley Editor |
| C. Alan Rawlins | Key Grip |
| Cynthia Pusheck | Camera Operator |
| Mark Fay | Boom Operator |
| Kristen Young | Assistant Editor |
| Herbert Dwight Raymond IV | First Assistant Editor |
| Chad Darnell | Extras Casting |
| Kim Ju | Extras Casting |
| Kelly Belmonte | Assistant Makeup Artist |
| Andy Dorowsky | Assistant Chief Lighting Technician |
| Daniel Craven | Assistant Editor |
| Wayne Cerullo | Pilot |
| Tom Schaus | Pilot |
