 | Tom Cruise als Ethan Hunt |
 | Paula Patton als Jane Carter |
 | Simon Pegg als Benjamin 'Benji' Dunn |
 | Jeremy Renner als William Brandt |
 | Michael Nyqvist als Kurt Hendricks |
 | Vladimir Mashkov als Anatoly Sidorov |
 | Samuli Edelmann als Marius Wistrom |
 | Ivan Shvedoff als Leonid Lisenker |
 | Anil Kapoor als Brij Nath |
 | Léa Seydoux als Sabine Moreau |
 | Josh Holloway als Trevor Hanaway |
 | Pavel Kříž als Marek Stefanski |
 | Miraj Grbić als Bogdan |
 | Ilia Volok als Fog |
 | Goran Navojec als Burly Russian Prisoner |
 | Pavel Bezděk als Prison Guard |
 | Ladislav Beran als Control Room Guard |
 | Jan Filipenský als Control Room Guard |
 | Jiří Kraus als Control Room Guard |
| Ales Putik als Control Room Guard |
 | Tomáš Valík als Control Room Guard |
 | Pavel Cajzl als Prisoner |
 | Randy Hall als Prisoner |
 | Vitaly Kravchenko als Scraggy Tooth |
| Andrej Bestcastnyj als Kremlin Senate Building Desk Guard |
 | Mike Dopud als Kremlin Subcellar Hallway Guard |
 | Martin Hub als Kremlin Gate Security Guard |
 | Ivo Novák als Russian Agent |
| Anastasiya Novikova als Russian Hospital Nurse |
 | Marek Dobeš als Russian News Anchor |
 | Claudia Vašeková als Russian News Anchor |
 | Brian Caspe als British News Anchor |
 | Petra Lustigová als Anna Lisenker |
| Daniel Clarke als Alex Lisenker |
 | April Stewart als Swedish Translator (voice) |
| Gina Hirsch als IMF Operator |
| Ghaleb El Saadi als Dock Worker |
 | Andreas Wisniewski als The Fog's Contact |
| Mustafa Alyassri als Doctor Setting Sidorov's Nose |
| Michael Rys als Russian Sub Captain |
 | Dmitry Chepovetsky als Russian Sub Ensign |
 | Dawn Chubai als San Francisco News Anchor |
 | Nicola Anderson als Julia's Friend |
 | Keith Dallas als Julia's Friend |
 | Tammy Hui als Julia's Friend |
 | David Stuart als Julia's Friend |
| Sabrina Morris als Julia's Friend |
 | Michelle Monaghan als Julia Meade-Hunt (uncredited) |
 | Ving Rhames als Luther Stickell (uncredited) |
 | Tom Wilkinson als IMF Secretary (uncredited) |
 | Jessica Belkin als Girl on the Red Square (voice) (uncredited) |
 | Paul Lazenby als Kremlin Guard (uncredited) |
 | Stephen Lobo als SINGH Security Guard (uncredited) |
 | Roger Narayan als Engineer, Various (uncredited) |
 | Ali Olomi als Sheikh (uncredited) |
 | Mihály Szabados als Conductor (uncredited) |
 | Darren Shahlavi als Sabine Moreau's Bodyguard (uncredited) |
 | Teddy Newton als Mission Brief (voice) (uncredited) |
| Brad Bird | Director |
| Robert Elswit | Director of Photography |
| Michael Giacchino | Original Music Composer |
| André Nemec | Co-Producer |
| April Webster | Casting |
| Bryan Burk | Producer |
| Alyssa Weisberg | Casting |
| J.J. Abrams | Producer |
| Michael Kaplan | Costume Design |
| Tom Cruise | Producer |
| Jakub Dvorak | Assistant Director |
| Michael Queen | Compositors |
| Mike Marcuzzi | Visual Effects |
| Helen Jarvis | Supervising Art Director |
| David Ellison | Executive Producer |
| Matthew Stillman | Co-Producer |
| Luca Paracels | Consulting Producer |
| Pravesh Sahni | Associate Producer |
| Dana Goldberg | Executive Producer |
| David Minkowski | Co-Producer |
| Tom C. Peitzman | Co-Producer |
| Josh Appelbaum | Co-Producer |
| Jeffrey Chernov | Executive Producer |
| Tommy Harper | Co-Producer |
| Tabrez Noorani | Line Producer |
| Paul Schwake | Executive Producer |
| Paul Hirsch | Editor |
| Chris Beach | Assistant Art Director |
| Keii Johnston | Stunts |
| James D. Bissell | Production Design |
| Sachin Agarwal | Production Manager |
| Ali Sadoon | Production Manager |
| David Strangmüller | Third Assistant Director |
| Kasia Trojak | Second Unit Director |
| Evan Godfrey | Script Supervisor |
| Carl De Villiers | Third Assistant Director |
| Michael Salven | First Assistant Director |
| Stewart Bethune | Production Manager |
| Raj Acharya | First Assistant Director |
| Chad Belair | Third Assistant Director |
| Jiří Kolárský | Third Assistant Director |
| Mihir Lath | Assistant Director |
| Richard Stirling | Post Production Assistant |
| Udayan Baijal | Second Assistant Director |
| Martina Götthansova | Second Second Assistant Director |
| Geoffrey Hansen | First Assistant Director |
| Manjari Makijany | Second Second Assistant Director |
| Eddy Santos | Third Assistant Director |
| Rhonda Taylor | Third Assistant Director |
| Sunny Tiku | Assistant Director |
| Kimi Webber | Script Supervisor |
| Jan Ciboch | Production Assistant |
| Ana Oparnica Sebal | Second Unit Director |
| Mark Bunting | Second Assistant Director |
| Emma Day | Assistant Director Trainee |
| Brandon Lambdin | Second Assistant Director |
| Jeffrey Lynch | Second Unit Director |
| Jason Roberts | Second Assistant Director |
| Ian Robinson | Assistant Director |
| Lynn Andrews | Production Supervisor |
| Scott Thaler | Unit Production Manager |
| Lucie Burianová | Second Second Assistant Director |
| Tommy Harper | Unit Production Manager |
| Jana Hrbková | Production Manager |
| Dmitriy Shutko | Production Supervisor |
| Dan Bradley | Second Unit Director |
| Kubhaer T. Jethwani | Second Second Assistant Director |
| Joecy Shepherd | Additional Script Supervisor |
| Misha Bukowski | Second Assistant Director |
| Leigh Clarke | Unit Production Manager |
| David Heffler | Script Supervisor |
| Manish Chajlane | Production Manager |
| Kevin O'Neil | Second Second Assistant Director |
| Pavel Douvidzon | Production Supervisor |
| Aleksandr Samokhvalov | Unit Production Manager |
| Shelraj Patel | Assistant Director |
| Samarth Sahni | Third Assistant Director |
| Aditya Tendulkar | Third Assistant Director |
| Kirby Adams | Executive In Charge Of Production |
| Silvie Janculová | Unit Manager |
| Sanjay Kumar | Production Supervisor |
| Baris Cangokce | Third Assistant Director |
| Mimi Crowe | Third Assistant Director |
| Jakub Dvorak | Second Assistant Director |
| Chris Castaldi | First Assistant Director |
| Geoff Dibben | Second Assistant Director |
| Tommy Gormley | First Assistant Director |
| Bonnie Benwick | Unit Manager |
| Gauri Chadha | Assistant Director |
| Gordon Piper | Second Second Assistant Director |
| Brian Sepanzyk | Assistant Director Trainee |
| John Knoll | Visual Effects Supervisor |
| Russell Solberg | Stunt Coordinator |
| Shelly Ward | Stunts |
| William Morts | Stunts |
| Richard Epper | Stunts |
| Anna Dvorscik | Stunts |
| Scott Sproule | Stunts |
| Randy Hall | Fight Choreographer |
| Dave Lane | Stunts |
| Janene Carleton | Stunts |
| Pavel Cajzl | Stunt Coordinator |
| Gregg Smrz | Stunt Coordinator |
| Sham Kaushal | Stunt Coordinator |
| David Schultz | Stunts |
| Owen Walstrom | Stunt Coordinator |
| Casey O'Neill | Stunt Double |
| Chris Daniels | Stunts |
| Pavel Boušek | Stunts |
| Patricia Isaac | Stunts |
| David Lištván | Stunts |
| Robert Alonzo | Fight Choreographer |
| Krista Bell | Stunts |
| Nilo Ghajar | Stunts |
| Garvin Cross | Stunts |
| Markos Rounthwaite | Stunt Coordinator |
| David Hugghins | Stunts |
| Gary Rydstrom | Supervising Sound Editor |
| Gary Rydstrom | Sound Designer |
| Bruce Geller | Original Series Creator |
| André Nemec | Writer |
| Josh Appelbaum | Writer |
| Lalo Schifrin | Main Title Theme Composer |
| Rosemary Brandenburg | Set Decoration |
| Andrew Del Rosario | Set Decoration |
| Elizabeth Wilcox | Set Decoration |
| Prince Shah | Third Assistant Director |
| Todd Vaziri | Compositing Supervisor |
| Mickey Giacomazzi | Utility Stunts |
| Craig Kuehne | Compositor |
