 | Jordan Rodrigues als Liu Kang (voice) |
 | Jennifer Carpenter als Sonya Blade (voice) |
 | Joel McHale als Johnny Cage (voice) |
 | Patrick Seitz als Scorpion (voice) |
 | Dave B. Mitchell als Raiden / Kintaro / Sektor (voice) |
 | Bayardo De Murguia als Sub-Zero / Kuai Liang (voice) |
 | Fred Tatasciore als Shao Kahn (voice) |
 | Matthew Mercer als Smoke / Stryker (voice) |
 | Emily O'Brien als Jade / Mother (voice) |
 | Debra Wilson als D'Vorah (voice) |
 | Artt Butler als Shang Tsung / Cyrax / Shao Khan Soldier (voice) |
 | Robin Atkin Downes als Shinnok / Reiko (voice) |
 | Ike Amadi als Jax Briggs / One Being (voice) |
 | Grey DeLisle als Kitana / Satoshi Hasashi (voice) |
 | Matthew Yang King als Kung Lao (voice) |
 | Paul Nakauchi als Lin Kuei Grandmaster (voice) |
 | Matthew Lillard als Shaggy (voice) |
 | Kyle Wyatt als Mob Leader (voice) |
| Ethan Spaulding | Director |
| Jeremy Adams | Writer |
| Ed Boon | Creative Consultant |
| Sam Register | Executive Producer |
| Rick Morales | Producer |
| Dawn Merkel | Associate Producer |
| Alyessa Ornelas | Associate Producer |
| Ed Boon | Video Game |
| John Tobias | Video Game |
| James Krieg | Co-Producer |
| John Jennings Boyd | Original Music Composer |
| Eric V. Hachikian | Original Music Composer |
| Kyle Stafford | Editor |
| Steven Choi | Character Designer |
| Will Nichols | Character Designer |
| Irineo Maramba | Character Designer |
| Chris Glenn | Background Designer |
| Cameron Thompson | Background Designer |
| Matthew Bordenave | Storyboard Artist |
| Tim Divar | Storyboard Artist |
| Jeremy Polgar | Storyboard Artist |
| Keo Thongkham | Storyboard Artist |
| Christina Sotta | Storyboard Artist |
| Milo Neuman | Storyboard Artist |
| Daniel Eaton | Effects Supervisor |
| Matthew Girardi | Art Designer |
| Matthew Girardi | Art Direction |
| Frances E. Chang | Administration |
| Darren Griffiths | Online Editor |
| Harrison T. Barth | Assistant Editor |
| Michele Beeson | Assistant Editor |
| Gabriel Gianola | Assistant Editor |
| Agnes Kim | Casting |
| Wes Gleason | ADR Voice Casting |
| Sarah Noonan | Casting |
