 | Kenneth Branagh als Hercule Poirot |
 | Tom Bateman als Mr. Bouc |
 | Michelle Pfeiffer als Caroline Hubbard |
 | Johnny Depp als Edward Ratchett |
 | Josh Gad als Hector MacQueen |
 | Willem Dafoe als Gerhard Hardman |
 | Judi Dench als Natalia Dragomiroff |
 | Derek Jacobi als Edward Masterman |
 | Leslie Odom Jr. als Dr. Arbuthnot |
 | Daisy Ridley als Mary Debenham |
 | Penélope Cruz als Pilar Estravados |
 | Olivia Colman als Hildegarde Schmidt |
 | Lucy Boynton als Helena Andrenyi |
 | Marwan Kenzari als Pierre Michel |
 | Manuel Garcia-Rulfo als Biniamino Marquez |
 | Sergei Polunin als Count Rudolph Andrenyi |
 | Miranda Raison als Sonia Armstrong |
 | Phil Dunster als John Armstrong |
 | Hayat Kamille als Susanne Michel |
 | Joseph Long als Imam |
 | Gerard Horan als Aynesworth |
 | Rami Nasr als Mr. MacQueen |
 | Adam Garcia als Italian Fan |
 | Ziad Abaza als Ship Mate |
 | Asan N'Jie als Waiter |
 | Ekran Mustafa als Local Person |
 | Andy Apollo als Armed Policeman |
 | Sid Sagar als Attendant |
 | Michael Rouse als British Chief Inspector |
 | Matthew Hawksley als Waiter |
 | Kate Tydman als Chef |
 | Pip Jordan als Kitchen Car Sous Chef |
 | Yasmin Harrison als Dining Car Sous Chef |
 | Jack Riddiford als Police Captain |
 | Hadley Fraser als British Military Escort |
 | Maxime Durand als Jerusalem Orthodox Resident (uncredited) |
| Yassine Zeroual als Young Boy |
 | Kathryn Wilder als Prostitute |
 | Alaa Safi als Jewellery Merchant |
| Kenneth Branagh | Director |
| Agatha Christie | Novel |
| Michael Green | Screenplay |
| Lucy Bevan | Casting |
| Haris Zambarloukos | Director of Photography |
| Patrick Doyle | Original Music Composer |
| Mick Audsley | Editor |
| Jim Clay | Production Design |
| Dominic Masters | Supervising Art Director |
| Mark Gordon | Producer |
| Aditya Sood | Producer |
| Kenneth Branagh | Producer |
| Phil Harvey | Art Direction |
| Will Coubrough | Art Direction |
| Judy Hofflund | Producer |
| Hilary Strong | Executive Producer |
| William Moseley | Associate Producer |
| Winston Azzopardi | Line Producer |
| Andrew Ackland-Snow | Art Direction |
| Jordana Finkel | Art Direction |
| Simon Kinberg | Producer |
| Michael Schaefer | Producer |
| James Prichard | Executive Producer |
| Ridley Scott | Producer |
| Alexandra Byrne | Costume Design |
| Sam Dormer | Armorer |
| Nicoletta Mani | Script Supervisor |
| Martina Zammit Maempel | Costume Coordinator |
| Sam Brooke-Taylor | Set Costumer |
| David Watkins | Special Effects Supervisor |
| Jacinthe Côté | Visual Effects Producer |
| Sylvain Theroux | Visual Effects Supervisor |
| Pepe Pleguezuelos | ADR Supervisor |
| Rebecca Alleway | Set Decoration |
| Lucia Foster Found | Aerial Coordinator |
| Hamish Doyne-Ditmas | Second Unit Director of Photography |
| Dan Lowe | Rigging Gaffer |
| Jed Loughran | Sound Effects Editor |
| Chiara Ugolini | Key Makeup Artist |
| Carol Hemming | Makeup Designer |
| Sylvia Parker | Script Supervisor |
| Marc Wolff | Aerial Coordinator |
| Karolina Dziwinska | Digital Intermediate |
| Samir Foco | Sound Effects Editor |
| Wakana Yoshihara | Hair Department Head |
| Ryo Murakawa | Hairstylist |
| Ian Bunting | Draughtsman |
| Richard Sale | Assistant Costume Designer |
| Simone Feulner | Tailor |
| Rob Farris | Digital Intermediate |
| Georgina Cranmer | Digital Intermediate |
| Malcolm Huse | Key Grip |
| Luca Saccuman | Key Hair Stylist |
| Terry Archer | Set Costumer |
| Josiane Fradette | Visual Effects Producer |
| Nicola Dove | Still Photographer |
| Gordon Goodwin | Lighting Technician |
| Janet Kellock | Script Supervisor |
| Graham Sutton | Music Editor |
| James Rustad | CG Supervisor |
| Mathieu Raynault | Visual Effects Supervisor |
| Jonathan Spencer | Gaffer |
| Charlotte Malynn | Draughtsman |
| Matt Howsam | Visual Effects Coordinator |
| Lilly Blazewicz | Foley |
| Paulina Boneva | Makeup Artist |
| Paul Savulescu | Draughtsman |
| Edward Martin | 3D Generalist |
| Roger Pearce | Camera Operator |
| Emmet Cahill | Key Grip |
| Charlo Dalli | Art Direction |
| Dan Grace | Costume Supervisor |
| Omar Morsy | Animation Supervisor |
| Alberto Herrera | Visual Effects Coordinator |
| Adam Dale | Aerial Director of Photography |
| Emily Brockmann | Casting Associate |
| Cecile Tournesac | Music Editor |
| Veronique Messier Lauzon | Visual Effects Producer |
| James Mather | Supervising Sound Editor |
| Caroline Bradley | Set Costumer |
| Tessa Phillips | Set Costumer |
| Lawrence Hook | Digital Intermediate |
| Sam Madden | Lighting Technician |
| Gloria Pasqua Casny | Hairstylist |
| Dan Clay | Draughtsman |
| Charlotte Barnes | Digital Intermediate |
| Patrick Ledda | Visual Effects Supervisor |
| James Shannon | Dolby Consultant |
| Alexis Continente | Hairstylist |
| Wakana Yoshihara | Makeup Department Head |
| Quinn Robinson | Assistant Art Director |
| Kate Chadderton | Costume Coordinator |
| Mike Prestwood Smith | Sound Re-Recording Mixer |
| Robin Morrison | Music Editor |
| Irene Armit | Visual Effects Coordinator |
| Kyla Lebon | Visual Effects Coordinator |
| George Murphy | Visual Effects Supervisor |
| Ken Niederbaumer | Makeup Artist |
| Samuela Galea | Set Costumer |
| Maria Chamberlain | Digital Intermediate |
| Thora Woodward | First Assistant Editor |
| Kenneth Cassar | Special Effects Supervisor |
| Naveen Kumar | Visual Effects Coordinator |
| Stamos Triantafyllos | Steadicam Operator |
| Peter Burgis | Foley |
| Ben Meechan | Sound Effects Editor |
| Amelie Thomas | Visual Effects Coordinator |
| Vincent Poitras | Visual Effects Supervisor |
| Luke Redgrave | Camera Operator |
| Emma Clough | Assistant Art Director |
| Daniel Rogers | Health and Safety |
| Matthew Jenkins | Executive Producer |
| Guy List | Stunts |
| Martin Curry | First Assistant Director |
| Arran Topham | Stunt Double |
| Guiomar Alonso | Stunt Double |
| Shane Steyn | Stunt Double |
| Sam Stefan | Stunts |
| James O'Donnell | Stunt Coordinator |
| James Embree | Fight Choreographer |
| Leo Woodruff | Stunts |
| Ramon Álvarez | Stunts |
| Lewis Young | Stunts |
| Martin Wilde | Stunts |
| Edward Upcott | Stunts |
| Arran Topham | Stunts |
| Mens-Sana Tamakloe | Stunts |
| Shane Steyn | Stunts |
| James Stewart | Stunts |
| Sam Stefan | Stunt Double |
| Ben Simon | Stunts |
| Tom Rodgers | Stunts |
| Kierron Quest | Stunts |
| Peter Pedrero | Stunts |
| Justin Pearson | Stunts |
| Nora Henderson | Stunt Coordinator |
| Ray Nicholas | Stunts |
| Tina Maskell | Stunts |
| Derek Lea | Stunts |
| Ian Kay | Stunts |
| Rob Hunt | Stunts |
| Gary Hoptrough | Stunts |
| Tom Hatt | Stunts |
| James Harris | Stunts |
| Adam Garcia | Stunts |
| Josie Forman | Stunts |
| Neil Finnighan | Stunts |
| Rick English | Stunts |
| James Embree | Stunts |
| Levan Doran | Stunts |
| Efrem Paul Cockett | Stunt Double |
| Carlos Castillo | Stunts |
| Alan Calton | Stunts |
| Tom Boney | Stunts |
| Ashley Beck | Stunts |
| Lloyd Bass | Stunts |
| Guiomar Alonso | Stunts |
| Sina Ali | Stunts |
| Nathan Aldous | Stunts |
| Lucy Scarfe | Stand In |
| Maisie Caen-Reilly | Makeup Trainee |
| Naomi Donne | Makeup Artist |
| Marcelle Genovese | Makeup & Hair |
| Louise Young | Makeup Artist |
| Paul Biddiss | Military Consultant |
| Colin Nicolson | Production Sound Mixer |
