 | Ron Livingston als Peter Gibbons |
 | Jennifer Aniston als Joanna |
 | David Herman als Michael Bolton |
 | Ajay Naidu als Samir Nagheenanajar |
 | Diedrich Bader als Lawrence |
 | Stephen Root als Milton Waddams |
 | Gary Cole als Bill Lumbergh |
 | Richard Riehle als Tom Smykowski |
 | Ali Wentworth als Anne |
 | Joe Bays als Dom Portwood |
 | John C. McGinley als Bob Slydell |
 | Paul Willson als Bob Porter |
 | Kinna McInroe als Nina |
 | Todd Duffey als Chotchkie's Waiter |
 | Greg Pitts als Drew |
 | Michael McShane als Dr. Swanson |
| Linda Wakeman als Laura Smykowski |
| Jennifer Jane Emerson als Female Temp |
| Kyle Scott Jackson als Rob Newhouse |
 | Orlando Jones als Steve |
| Barbara George-Reiss als Lumbergh's Secretary |
 | Tom Schuster als Construction Foreman |
| Rupert Reyes als Mexican Waiter |
| Jackie Belvin als Swanson's Patient #1 |
| Gabriel Folse als Swanson's Patient #2 |
| Jesse De Luna als Cop at Fire |
 | Mike Judge als Chotchkie's Manager |
| Justin Possenti als Spectator |
 | Jack Betts als Judge |
 | Charissa Allen als Jogger (uncredited) |
| Samantha Inoue Harte als Initech Employee (uncredited) |
| Josh Bond als Initech Security Guard (uncredited) |
| R.C. Keene als Rush Hour Driver (uncredited) |
 | Spencer Kayden als Office Worker (uncredited) |
| K. Todd Lytle als Rush Hour Driver (uncredited) |
 | Cassie Townsend als Rush Hour Driver's Partner (uncredited) |
| Heath Young als Spectator (uncredited) |
| Mike Judge | Director |
| Tim Suhrstedt | Director of Photography |
| Nancy Klopper | Casting |
| Edward T. McAvoy | Production Design |
| Mike Judge | Screenplay |
| Daniel Rappaport | Producer |
| Michael Rotenberg | Producer |
| Guy Riedel | Executive Producer |
| John Frizzell | Original Music Composer |
| David Rennie | Editor |
| Adele Plauche | Art Direction |
| Melinda Eshelman | Costume Design |
| Eric Norris | Stunts |
| Don Pike | Stunts |
| Rob King | Stunt Coordinator |
| Gary Pike | Stunts |
| Janice Janecek | Costume Supervisor |
| Lee Hunsaker | Set Costumer |
| Kimmie Furlong | Set Costumer |
| Stacy Brownrigg | Sound Mixer |
| Tony Eckert | Foley Mixer |
| Bruce Lacey | ADR Editor |
| David Lucarelli | ADR Recordist |
| Frank 'Pepe' Merel | Foley Recordist |
| Tom Myers | Sound Re-Recording Mixer |
| E. Larry Oatfield | Sound Effects Editor |
| Charleen Richards-Steeves | ADR Mixer |
| Gary Rizzo | Sound Re-Recording Mixer |
| Larry Schalit | ADR Editor |
| Michael Semanick | Sound Re-Recording Mixer |
| Robert Shoup | Supervising Sound Editor |
| Dennie Thorpe | Foley Artist |
| Jana Vance | Foley Artist |
| Carla Curry | Set Decoration |
| Christina Fong | Second Assistant Director |
| Rip Murray | First Assistant Director |
| April Crump | Set Dresser |
| Marc Dabrusin | Set Dresser |
| Steve Sawhill | Set Dresser |
| Robert Calvert | Special Effects |
| Steve Dearth | Special Effects |
| Paul J. Lombardi | Special Effects Coordinator |
| Charles Papert | Camera Operator |
| Bob Field | Gaffer |
| Cheryl Starbuck | Script Supervisor |
| Beth Sepko | Extras Casting |
