 | Burt Reynolds als Charlie B. Barkin (voice) |
 | Dom DeLuise als Itchy Itchiford (voice) |
 | Judith Barsi als Anne-Marie (voice) |
 | Melba Moore als Whippet Angel (voice) |
| Daryl Gilley als Dog Caster (voice) |
| Candy Devine als Vera (voice) |
 | Charles Nelson Reilly als Killer (voice) |
 | Vic Tayback als Carface (voice) |
| Rob Fuller als Harold (voice) |
| Earleen Carey als Kate (voice) |
| Anna Manahan als Stella Dallas (voice) |
 | Nigel Pegram als Sir Reginald (voice) |
 | Loni Anderson als Flo (voice) |
 | Ken Page als King Gator (voice) |
 | Godfrey Quigley als Terrier (voice) |
| Jay Stevens als Mastiff (voice) |
| Dan Molina als The Don Bluth Players (voice) |
| Dan Kuenster als The Don Bluth Players (voice) |
| Mark Swan als The Don Bluth Players (voice) |
 | David N. Weiss als The Don Bluth Players (voice) |
| Dick Zondag als The Don Bluth Players (voice) |
| Taylor Swanson als The Don Bluth Players (voice) |
 | Jack Angel als (voice) (uncredited) |
 | Nancy Cartwright als (voice) (uncredited) |
 | Patrick Pinney als (voice) (uncredited) |
| Morris F. Sullivan | Executive Producer |
| Ken Cromar | Story |
| Larry Leker | Story |
| George A. Walker | Executive Producer |
| Lisa Dorney | Editor |
| Gary Goldman | Story |
| John Pomeroy | Producer |
| Don Bluth | Production Design |
| Linda Miller | Story |
| Larry Leker | Production Design |
| John Pomeroy | Story |
| Don Bluth | Director |
| John K. Carr | Editor |
| David J. Steinberg | Story |
| Gary Goldman | Producer |
| Don Bluth | Story |
| David N. Weiss | Story |
| David N. Weiss | Screenplay |
| Monica Parker | Story |
| Don Bluth | Producer |
| Guy Shulman | Story |
| Ralph Burns | Original Music Composer |
| Darlie Brewster | Animation |
| Dan Harder | Animation |
| Jeannette Maher-Manifold | Camera Operator |
| Fred A. Reilly | Layout |
| Dave Kupczyk | Animation |
| Michael Connell | Music Editor |
| Janet Hirshenson | Casting |
| Gerry Humphreys | Sound Re-Recording Mixer |
| Jane Jenkins | Casting |
| Dean Humphreys | Sound Re-Recording Mixer |
| Marci Liroff | Casting |
| John K. Carr | Supervising Sound Editor |
| Dan Kuenster | Co-Director |
| Gary Goldman | Co-Director |
| Charles Strouse | Songs |
| T.J. Kuenster | Songs |
