 | Rosamund Pike als Marie Curie |
 | Sam Riley als Pierre Curie |
 | Aneurin Barnard als Paul Langevin |
 | Simon Russell Beale als Professor Lippmann |
 | Katherine Parkinson als Jeanne Langevin |
 | Sian Brooke als Bronia Sklodowska |
 | Anya Taylor-Joy als Irène Aged 18 |
 | Yvette Feuer als Carla |
 | Mirjam Novak als Nurse |
 | Ralph Berkin als Doctor |
| Faye Bradbrook als Bronia's Maid |
 | Drew Jacoby als Loie Fuller |
 | Harriet Turnbull als Young Marie |
 | Georgina Rich als Marie's Mother |
| Elise Alexandre als Young Bronia |
| Dóra Köves als Pierre's Mother |
 | Mark Phelan als Delivery Man |
 | Alexis Latham als Guard |
 | Indica Watson als Irène Aged 6 |
 | Federica Fracassi als Eusapia |
 | Demetri Goritsas als Dr Jenkins |
| Charles Tumbridge als Peter |
 | Corey Johnson als Adam |
 | Péter Fancsikai als Henrik |
 | Paul Albertson als Tibbets |
| Yasuhito Ishikawa als Japanese Man |
| Arthur Bateman als Young Pierre |
 | Jennifer White als Radium Dancer |
| Ema Yuasa als Radium Dancer |
| Nicola Willis als Radium Dancer |
| Acacia Schachte als Radium Dancer |
| Joseph Kudra als Radium Dancer |
 | Robbie Moore als Radium Dancer |
| Jonas Vanderkerckhove als Radium Dancer |
| Oscar Ramos als Radium Dancer |
 | Richard Pepple als Lester Jackson |
 | Alex Bartram als Daniel |
 | Isabella Miles als Ève Aged 4 |
 | Ariella Glaser als Irène Aged 11 |
| Martin Anzor als Dimitri |
 | Cara Bossom als Ève Aged 11 |
 | Edward Davis als Frédéric |
 | Tim Woodward als Alexandre |
| Tamás Szabó als Bernard |
| Marjane Satrapi | Director |
| Tim Bevan | Producer |
| Eric Fellner | Producer |
| Anthony Dod Mantle | Director of Photography |
| Stéphane Roche | Editor |
| Michael Carlin | Production Design |
| Jack Thorne | Screenplay |
| Paul Webster | Producer |
| Shana Eddy-Grouf | Executive Producer |
| Ron Halpern | Executive Producer |
| Ildikó Kemény | Co-Producer |
| Caroline Levy | Co-Producer |
| David Minkowski | Co-Producer |
| Evgueni Galperine | Original Music Composer |
| Sacha Galperine | Original Music Composer |
| Géza Kerti | Art Direction |
| Zoltán Frank | Set Decoration |
| Robert Wischhusen-Hayes | Set Decoration |
| Consolata Boyle | Costume Design |
| Andrew Caller | Sound Re-Recording Mixer |
| Steve Fanagan | Sound Designer |
| Csongor Fazekas | Boom Operator |
| András Horváth | Boom Operator |
| Csaba Major | Sound Mixer |
| Ian Tapp | Sound Re-Recording Mixer |
| Tibor Lázár | Art Direction |
| Sonja Nenadić | Standby Art Director |
| Zsuzsa Kismarty-Lechner | Supervising Art Director |
| Nige Watson | First Assistant Director |
| Phoebe Billington | Script Supervisor |
| Gabor Schmidt | Best Boy Grip |
| Daniel Czinkota | Data Wrangler |
| Attila Tumbász | Digital Imaging Technician |
| Vilmos Keszler | Dolly Grip |
| József Kiss | Electrician |
| Péter Orosz | Electrician |
| Chris Summers | First Assistant Camera |
| Attila Szücs | Key Grip |
| Eduardo Luján | Key Grip |
| Gergely Hajba | Second Assistant Camera |
| Kristóf Párdányi | Second Assistant Camera |
| Michael Wood | Second Unit Director of Photography |
| Laurie Sparham | Still Photographer |
| Máté Oláh | Video Assist Operator |
| Beáta Milák | Assistant Makeup Artist |
| Denise Kum | Hair Designer |
| Lorraine Glynn | Hairstylist |
| Erzsébet Rácz | Hair Supervisor |
| Nuria Mbomio | Makeup & Hair |
| Lesley Smith | Makeup & Hair |
| Réka Görgényi | Makeup Artist |
| Denise Kum | Makeup Designer |
| Éva Kozma | Makeup Supervisor |
| Chris Fitzpatrick | Prosthetic Supervisor |
| Jina Jay | Casting |
| Eliza Heslop | Casting Assistant |
| Kálmán Burai | Casting Coordinator |
| Katalin Baranyi | Casting Director |
| Balázs Kovács | Extras Casting |
| Melinda Derdak | Extras Casting Assistant |
| Johanna Garrad | Assistant Costume Designer |
| José Vico | Assistant Costume Designer |
| Sally Crees | Costume Assistant |
| Yannick Gondran | Costume Assistant |
| Marion Weise | Costume Supervisor |
| Grace Clark | Dresser |
| László Donkó | Key Costumer |
| Dóra Papp | Principal Costumer |
| Zoltán Bus | Supervising Armorer |
| Hardy Ilona | Art Department Coordinator |
| Bence Kalmár | Assistant Art Director |
| Krisztina Szilágyi | Assistant Art Director |
| László Szirmai | Assistant Art Director |
| Balázs Bakró | Assistant Property Master |
| Gergely Álmos | Draughtsman |
| Jannick Guillou | Graphic Designer |
| Arnold Gerhát | Leadman |
| Sandro Ercolini | Painter |
| Adam McCreight | Property Master |
| Nandi Kiss | Set Decorating Coordinator |
| Márton Nedjalkov | Set Dresser |
| Rodney J. McFall | CG Supervisor |
| Attila Gasparetz | Digital Compositor |
| Erdem Gonulay | Digital Compositor |
| Yudai Kato | Digital Compositor |
| Christopher Lucas Maw | Digital Compositor |
| Hannah Sornay | Digital Compositor |
| Petko Zhivkov | Digital Compositor |
| Jolien Buijs | Visual Effects Coordinator |
| Marta Matuszewska | Visual Effects Coordinator |
| Quiben Jack | Visual Effects Editor |
| Robin Hinch | Visual Effects Editor |
| Zafar Janjua | Visual Effects Producer |
| Simon Hughes | Visual Effects Supervisor |
| Gábor Kiszelly | Special Effects Supervisor |
| Gergely Csóri | Special Effects Technician |
| Maria Chamberlain | Additional Colorist |
| Anna Stalter | Colorist |
| Rob Farris | Digital Intermediate |
| Alexander Phillips | Digital Intermediate Assistant |
| Karolina Dziwinska | Digital Intermediate Producer |
| Suhaila Mahmoud | Digital Intermediate Producer |
| George Adams | First Assistant Editor |
| Thora Woodward | First Assistant Editor |
| Chloe Warner-Harris | Online Editor |
| Marcsi Tóth | Production Coordinator |
| Regina Ruffini | Production Coordinator |
| Angela Moneke | Production Coordinator |
| Joanne Dixon | Production Supervisor |
| Lauren Redniss | Book |
