 | Jeffrey Combs als Herbert West |
 | Bruce Abbott als Dan Cain |
 | Barbara Crampton als Megan Halsey |
 | David Gale als Dr. Carl Hill |
 | Robert Sampson als Dean Alan Halsey |
 | Carolyn Purdy-Gordon als Dr. Harrod |
 | Peter Kent als Melvin the Re-Animated (uncredited) |
 | Ian Patrick Williams als Swiss Professor (uncredited) |
 | Bunny Summers als Swiss Woman Doctor (uncredited) |
 | Al Berry als Dr. Gruber (uncredited) |
| Barbara Pieters als Nurse |
| Annyce Holzman als E-R Patient Corpse |
| Velvet Debois als Slit Wrist Girl Corpse |
| Robert Holcomb als Motorcycle Accident Corpse |
| Mike Filloon als Bullet Wound to Face Corpse |
| James Earl Cathay als Psycho Ward Guard #2 |
 | James Ellis als Psycho Ward Guard #1 |
| Derek Pendleton als Swiss Policeman #1 |
| Gene Scherer als Swiss Policeman #2 |
| Gerry Black als Mace |
| Lee Percy | Editor |
| Mac Ahlberg | Director of Photography |
| Dan Bradley | Stunt Coordinator |
| Stuart Gordon | Director |
| Stuart Gordon | Writer |
| Brian Yuzna | Producer |
| Richard Band | Original Music Composer |
| Robin Lewis-West | Costume Design |
| Dennis Paoli | Writer |
| John Carl Buechler | Special Effects Makeup Artist |
| H.P. Lovecraft | Novel |
| H.P. Lovecraft | Story |
| Robert A. Burns | Art Direction |
| Everett Burrell | Special Effects Makeup Artist |
| John Kwiatkowski | Sound Editor |
| Dennis Stuart Murphy | Executive In Charge Of Production |
| Michael Avery | Executive Producer |
| Anthony Doublin | Special Effects Makeup Artist |
| Anthony Barnao | Casting |
| Bret Culpepper | Special Effects |
| Stanley B. Gill | Sound Recordist |
| William Norris | Writer |
| Bob Greenberg | Associate Producer |
| John Naulin | Special Effects Makeup Artist |
| Bruce William Curtis | Executive Producer |
| Charles Donald Storey | Associate Producer |
| Robin Burton | Costume Design |
