 | Matthew McConaughey als Dirk Pitt |
 | Penélope Cruz als Dr. Eva Rojas |
 | Steve Zahn als Al Giordino |
 | Lennie James als General Zateb Kazim |
 | Lambert Wilson als Yves Massarde |
 | William H. Macy als Admiral Jim Sandecker |
 | Rainn Wilson als Rudi Gunn |
 | Glynn Turman als Dr. Frank Hopper |
 | Jude Akuwudike als Imam |
 | Clint Dyer als Oshodi |
 | Delroy Lindo als Carl |
 | Robert Cavanah als Captain Tombs |
| Paulin Fodouop als Modibo |
 | Abdul Salis als Oumar |
 | Maurice Lee als Zakara |
| Tosin Sanyalo als Azikiwe Nwokolo |
 | Rakie Ayola als Mrs. Nwokolo |
 | Patrick Malahide als Ambassador Polidori |
 | Emmanuel Ighodaro als Kazim's Officer Asselar |
| Mark Aspinall als Lawyer |
| Christopher Bello als Train Driver |
 | Nicholas Beveney als Gunboat 1 Officer |
| Empotoe Bosage als Pick Up Truck Guard |
| Matthew Flynn als 1st Lieutenant, Ironclad |
| Ouahbou Houcine als Tuareg Village Boy #1 |
 | Daniel Njo Lobé als Tuareg Sangare |
 | Francis Magee als Fuse Cutter |
| Thierno Amath Mbaye als Pick Up Truck Driver |
 | Femi Ogunbanjo als Modibo's Tuareg #2 |
 | Eddie Osei als Train Guard |
| Nathan Osgood als Gun Captain |
| Lahcen Ouezgane als Tuareg Village Boy #2 |
 | Robert Paterson als NUMA Crew Member |
 | Christopher Saul als Pilot, Ironclad |
| Billy Seymour als Powder Monkey |
 | Mark Springer als Solar Plant Guard |
| Celestine Vita als Old Woman in Labbezanga |
| Mark Wells als Sailor Who Drops Gold |
| James V. Hart | Screenplay |
| William J. Immerman | Executive Producer |
| Matthew McConaughey | Executive Producer |
| Howard Baldwin | Producer |
| Gus Gustawes | Executive Producer |
| Breck Eisner | Director |
| Nina Gold | Casting |
| Stephanie Austin | Producer |
| Allan Cameron | Production Design |
| Chris Thompson | Line Producer |
| Mace Neufeld | Producer |
| Karen Elise Baldwin | Producer |
| Andrew MacRitchie | Editor |
| Thomas Dean Donnelly | Screenplay |
| Seamus McGarvey | Director of Photography |
| Clint Mansell | Original Music Composer |
| Scott Thaler | Line Producer |
| Anne McCarthy | Casting |
| Clive Cussler | Novel |
| John C. Richards | Screenplay |
| Henning Molfenter | Co-Producer |
| Denise O'Dell | Co-Producer |
| Mike Phillips | Co-Producer |
| Thierry Potok | Co-Producer |
| Mark Albela | Co-Producer |
| Nick Morton | Co-Producer |
| David Barron | Co-Producer |
| William H. Brown | Co-Producer |
| Joshua Oppenheimer | Screenplay |
| Anna Pinnock | Set Decoration |
| Karen Dawson | Makeup Artist |
| Karen Dawson | Hairstylist |
| Whitney James | Makeup Artist |
| Jean Bourne | Script Supervisor |
| Martin Samuel | Hairstylist |
| Lis Kern | Associate Producer |
| Andrew Reif | Associate Producer |
| Vicki Dee Rock | Executive Producer |
| Katryna Samut-Tagliaferro | Production Coordinator |
| Paul Munro | Boom Operator |
| Charles Howell | Visual Effects Coordinator |
| Nigel Permane | First Assistant Camera |
| Hafid Balafrej | Unit Production Manager |
| Gavin Buckley | Visual Effects Editor |
| Bill Barringer | Location Manager |
| Charif Lemhemdi | Cableman |
| Peter Chester | Best Boy Electric |
| Aileen Seaton | Hair Designer |
| Gavin Walters | Rigging Gaffer |
| Leslie Shatz | Sound Designer |
| David Manzanares | Location Scout |
| John Nixon | Armorer |
| James Benson | 3D Artist |
| Anna Skrein | Art Department Coordinator |
| John Cormican | Prosthetic Makeup Artist |
| Antonio Bloch | Sound Recordist |
| David Hyde | Technical Supervisor |
| Andy Bell | Electrician |
| Nicholas Dodd | Orchestrator |
| Dominic Tuohy | Special Effects Supervisor |
| Cristina Sopeña | Costume Supervisor |
| Scott Thaler | Production Manager |
| Nigel Mills | Supervising Sound Editor |
| Tim Keene | Visual Effects Producer |
| Keith Hamshere | Still Photographer |
| Lee Walters | Gaffer |
| Dina Eaton | Music Editor |
| Lindsay Fellows | Music Supervisor |
| Chris Munro | Sound Mixer |
| Saskia Green | Art Department Assistant |
| Christopher Newman | First Assistant Director |
| Giles Masters | Art Direction |
| Stuart Clarke | Scenic Artist |
| Richard Briscoe | Digital Compositors |
| Marc Homes | Assistant Art Director |
| Bradley Woodbridge | Painter |
| Gary Hutchings | Key Grip |
| John Marzano | Aerial Director of Photography |
| Stephen McGregor | Carpenter |
| Dan Frye | Propmaker |
| Susan d'Arcy | Unit Publicist |
| Sophie Drouin | Production Accountant |
| Bruce Gordon | Sculptor |
| Brendan Gunn | Dialect Coach |
| Karim Kahkahni | Set Production Assistant |
| Tom Harrison-Read | First Assistant Editor |
| Tony Reading | Art Direction |
| Jan Meade | Projection |
| Paul Couch | Standby Painter |
| David Holliday | Grip |
| Carmila Gittens | Special Effects Coordinator |
| Mark Auguste | Sound Effects Editor |
| Mara Bryan | Visual Effects Supervisor |
| James Seddon | Dolby Consultant |
| Gary Webber | Stand In |
| Lee Sheward | Stunt Coordinator |
| Paul Apted | First Assistant Sound Editor |
| Steve Griffin | Stunts |
| Marta Ortega | Costume Mistress |
| Sylvia Steinbrecht | Assistant Set Dresser |
| Stephen Challenor | Supervising Carpenter |
| Peter Gleaves | ADR Mixer |
| David Raines | Additional Sound Re-Recording Mixer |
| Steve Brooke Smith | Assistant Camera |
| Toby Glover | Graphic Designer |
| Kathy Ducker | Hair Assistant |
| Alexander Beddow | ADR Recordist |
| Matt Curtis | Title Designer |
| Silvana Sacco | Costume Illustrator |
| Temple Clark | Storyboard Artist |
| Scott MacIntyre | Special Props |
| Adam Aldridge | Special Effects Technician |
| E. J. Foerster | Second Unit Director |
| Sze-Wun Li | Apprentice Sound Editor |
| Stephen Conway | Dressing Prop |
| Felicity Cottrell | Foley Artist |
| Guiomar Alonso | Stunt Double |
| Tarik Ait Ben Ali | Additional Second Assistant Director |
| Tom Glaisyer | Third Assistant Director |
| Jack Dyer | Construction Buyer |
| Lahcen Abbana | Costume Assistant |
| Patricia Aguirre | Dresser |
| Ben Howarth | Second Assistant Director |
| Tony Gil | Best Boy Grip |
| Neill Gorton | Prosthetic Designer |
| Luis Casacuberta | Second Second Assistant Director |
| Tim Battersby | Focus Puller |
| Mark Wright | Negative Cutter |
| Mustapha Adidou | Assistant Location Manager |
| Vanessa Baker | ADR Voice Casting |
| Susan Luciani | Camera Trainee |
| Daryl Bristow | Wardrobe Supervisor |
| Gary Lane | Wardrobe Assistant |
| Jack James | Online Editor |
| Diane Conn | Executive Assistant |
| Michael Conran | Health and Safety |
| Ben Pugh | Production Assistant |
| Mercedes Barbod | Production Secretary |
| Christopher Russell | Post Production Coordinator |
| Kathy Hughes | Additional Script Supervisor |
| Ahmed Achouba | Assistant Accountant |
| Usha Chaman | Assistant Production Coordinator |
| Adam Inglis | Colorist |
| Rodrigo López | Second Assistant Camera |
| Marcus Alexander | Digital Intermediate Producer |
| Nicholas Dodd | Conductor |
| Peter Hornbuckle | Wardrobe Master |
| Ahmed Hajji | Production Runner |
| Marc Wolff | Aerial Coordinator |
| John McHale | Pilot |
| Conor Coughlan | Pyrotechnician |
| Bacha | Casting Assistant |
| Kristine Bochum | Second Assistant Accountant |
| Larry Knox | Generator Operator |
| Neil Miller | Matte Painter |
| Jan Hogevold | Production Executive |
| Elabdi Abdelhadi | Location Assistant |
| Naima Alaoui | Location Coordinator |
| Philip Alton | ADR Editor |
| Philip Alton | Dialogue Editor |
| Mark Norby | Stunt Double |
| Tracey Eddon | Stunts |
| Harvey Harrison | Second Unit Director of Photography |
| Leslie Shatz | Sound Re-Recording Mixer |
| Andy Hennigan | Production Controller |
| Frédéric Bovis | Unit Production Manager |
| Ahmed Hatimi | First Assistant Director |
| Pedro Sopeña | First Assistant Director |
| Yann Marie Faguet | Additional Second Assistant Director |
| Carlos Santana | Second Assistant Director |
| Kai Martin | Stunt Double |
| Adam Kirley | Stunt Double |
| John Allenby | Property Master |
| Luke Haddock | Video Assist Operator |
| Ray Meere | Loader |
| Jennie Paddon | Clapper Loader |
| Ryan Taggart | Clapper Loader |
| Iain Mackay | Clapper Loader |
| Carlos De Carvalho | Focus Puller |
| John Jordan | Focus Puller |
| Rawdon Hayne | Focus Puller |
| Peter Robertson | "A" Camera Operator |
| Rodrigo Gutierrez | "B" Camera Operator |
| Simon Baker | "C" Camera Operator |
| Neil Morrill | Prosthetic Makeup Artist |
| Deborah Murphy | Prosthetic Makeup Artist |
| Anna B. Sheppard | Costume Designer |
| Natalie Burns-Spence | Costume Assistant |
| Antonia Kraskowski | Costume Assistant |
| Peter Paul | Wardrobe Master |
| David Whiteing | Wardrobe Assistant |
| Hassan Taghriti | Key Costumer |
| Vanessa Marshall | Tailor |
| Elspeth Threadgold | Tailor |
| Sharon Billingham | Ager/Dyer |
| Tom Hornsby | Wardrobe Supervisor |
| Lee Croucher | Wardrobe Master |
| Una Hill | Production Coordinator |
| Widad Taha | Production Coordinator |
| Mona Benjamin | Production Coordinator |
| Faye Villalbe | Production Coordinator |
| Luci Lenox | Production Coordinator |
| Kelly Taylor-Dias | Assistant Production Coordinator |
| Jo Wallett | Production Secretary |
| Samantha Smith | Second Second Assistant Director |
| James Chasey | Third Assistant Director |
| Francisco Barrionuevo | Third Assistant Director |
| Khalid Boulasri | Location Manager |
| Jeremy Bau | Location Manager |
| José María González Sinde | Location Manager |
| Salvador Yagüe | Location Manager |
| Félix Rosell | Location Manager |
| Mohamed Chrouate | Assistant Location Manager |
| Khalid Bouslamti | Assistant Location Manager |
| Souheil Hallaoui | Assistant Location Manager |
| Ismail Madkouri | Assistant Location Manager |
| Teddy Villalba | Assistant Location Manager |
| Alba Tovar | Assistant Location Manager |
| Ricardo Serrano | Location Assistant |
| María Cabello | Location Assistant |
| Sylvia Mackintosh | Production Accountant |
| Betty Williams | Production Accountant |
| Chantal Malrat | Production Accountant |
| Ali Moshref | Production Accountant |
| Sammy Horton | Assistant Accountant |
| Anne Marie Gormley | Assistant Accountant |
| Lynne Greenshields | Assistant Accountant |
| Abderahim Taha | Assistant Accountant |
| Saray Perez | Assistant Accountant |
| Gemma Todd Smithers | Assistant Accountant |
| Deborah Leakey | Assistant Accountant |
| Amine Ameriah | Assistant Accountant |
| Alain Dominiecki | Assistant Accountant |
| Ibtissam Semmar | Assistant Accountant |
| Ahmed Berrami | Assistant Accountant |
| Maria Jose Argenta | Assistant Accountant |
| Antony Gibbs | Additional Editing |
| Billy A. Campbell | VFX Editor |
| Gavin Buckley | VFX Editor |
| Philip Hedgecock | First Assistant Editor |
| James Herbert | First Assistant Editor |
| Jon Olive | Sound Designer |
| Malcolm Sheehan | Best Boy Grip |
| David Maund | Grip |
| Peter Harris | Electrician |
| Perry Cullen | Electrician |
| Steve Blythe | Electrician |
| Dean Houlton | Electrician |
| Paul Harris | Electrician |
| Adrian Mackay | Electrician |
| Terry Roberts | Electrician |
| Michael Buxton | Libra Head Technician |
| Steve Mayer | Sound Effects Editor |
| Andy Kennedy | Sound Effects Editor |
| Sam Southwick | Foley Editor |
| Conor Mackey | Assistant Sound Editor |
| Andy Walker | Assistant Sound Editor |
| Craig Irving | Sound Re-Recording Mixer |
| Christopher Wilson | Sound Re-Recording Mixer |
| Mark Lafbery | ADR Mixer |
| Mark Lafbery | Foley Mixer |
| Jack Stew | Foley Artist |
| Andy Thompson | ADR Mixer |
| Frederic Evard | Standby Art Director |
| Patricia Johnson | Assistant Art Director |
| Jordi Yria Roca | Assistant Art Director |
| John Greaves | Storyboard Artist |
| Christopher Glass | Storyboard Artist |
| Philip Keller | Storyboard Artist |
| Robert Camron | Assistant Set Decoration |
| John O'Shaughnessy | Set Decoration Buyer |
| Said El Kounti | Set Decoration Buyer |
| Maite Sánchez | Set Dressing Buyer |
| Aziz Hamichi | Art Department Assistant |
| Joss Skottowe | Armorer |
| Sascha Robey | Armorer |
| Tony Smith | Armorer |
| Garth Gutteridge | Special Effects Technician |
| Tim Jordan | Special Effects Technician |
| Jason Marsh | Special Effects Technician |
| Matthew G. Armstrong | Special Effects Technician |
| Joe Halford | Special Effects Technician |
| Zoila Gomez | Production Coordinator |
| Marsha Trainer | Production Coordinator |
| Kelly DeTample | Assistant Production Coordinator |
| Kawtar Bellafquih | Production Secretary |
| Zine Eddine Ibnoujabal | Casting |
| Natalie Charon | Casting |
| Stephen Moore | Casting Assistant |
| Rosalie Clayton | Casting Assistant |
| Freddy Luis | Casting Assistant |
| Heidi Snoe | Casting Assistant |
| Gora Mbaye | Casting Assistant |
| Russell Atherton | Set Medic |
| Paul Cooke | Set Medic |
| Steve Parry | Set Medic |
| Stuart Crichton | Set Medic |
| Suzanne Bowdler | Set Medic |
| David Adamthwaite | Set Medic |
| Rory Aitken | Producer's Assistant |
| Diane Conn | Producer's Assistant |
| John Chaney | Actor's Assistant |
| Anil Kurian | Executive Producer's Assistant |
| Nathon S. Lewis | Actor's Assistant |
| Christina Giffen | Actor's Assistant |
| Harry Humphries | Technical Advisor |
| Ray Barrett | Construction Manager |
| Pedro de la Fuente | Construction Manager |
| Gerry Gore | Transportation Coordinator |
| Mahjoub Nejma | Transportation Captain |
| Barry Stevenson | Driver |
| Gordon Curran | Driver |
| Rob Hempenstall | Driver |
| John Dawson | Driver |
| Lee Taylor | Driver |
| Mike Wheeler | Driver |
| Tom Gillett | Driver |
| Jason Taylor | Driver |
| Eddie Kay | Driver |
| Steve Lamonby | Picture Car Coordinator |
| Abdenabi Izlaguen | Picture Car Coordinator |
| James Lamb | Visual Effects Producer |
| Cedric Proust | Animal Wrangler |
| Anna Cassina | Unit Production Manager |
| Terry Madden | Second Unit First Assistant Director |
| Rachid Bouzida | Second Unit First Assistant Director |
| Víctor Molero | Standby Art Director |
| Enrique Gutierrez | Standby Carpenter |
| Peio Villalba | Standby Painter |
| Gary Spratling | "A" Camera Operator |
| Carlos Cabeceràn | "B" Camera Operator |
| Mike Evans | Focus Puller |
| Pepe Martinez | Focus Puller |
| Stephen Evans | Clapper Loader |
| Nicolas Garcia | Video Assist Operator |
| Elias Artalejo | Video Assist Operator |
| Aramís Rubio | Boom Operator |
| Susana Sánchez | Makeup Artist |
| Nuria Vela | Hairstylist |
| Paquita Núñez | Hairstylist |
| Julie Brown | Script Supervisor |
| Aurora Yufera | Production Coordinator |
| Soumaya Bellafquih | Production Secretary |
| Hassan Marouch | Production Runner |
| Arnaud Duterque | Location Manager |
| Khalid Awtoul | Assistant Location Manager |
| Marwan Darif | Assistant Location Manager |
| Stephen Foster | Gaffer |
| Paco Caceres | Gaffer |
| Paco Caceres | Best Boy Electric |
| Steve Blythe | Generator Operator |
| Kenneth Atherfold | Key Grip |
| Toni Gil | Best Boy Grip |
| Morchid El Edrissi | Grip |
| Xavi Gordi | Grip |
| Manuel Alvarez | Standby Carpenter |
| David McKay | Libra Head Technician |
| Stephen Morley | Still Photographer |
| Ceri Nichols | Special Effects Technician |
| Oriol Julià | Electrician |
| Ruben Freixas | Electrician |
| Debora Witte | Electrician |
| Marc Vives | Electrician |
| Abderrahim Bissar | Electrician |
| Lance Julian | Marine Coordinator |
| Helen Judd | Visual Effects Coordinator |
| Sandro Henriques | Rotoscoping Artist |
| Angie Wills | Visual Effects Producer |
| Fernanda Moreno | 3D Animator |
| Jamie Gigot | 3D Modeller |
| Fay McConkey | Visual Effects Producer |
| Ryan Cook | CG Supervisor |
| Richard Clarke | CG Supervisor |
| Murray Barber | Compositor |
| Claire Inglis | Compositor |
| Ivan Mena | Compositor |
| Cristina Puente | Compositor |
| Jelena Stojanovic | Compositor |
| Ciaran Crowley | Compositor |
| Alex Ireland | Compositor |
| Alice Mitchell | Compositor |
| Matthew Shaw | Compositor |
| Sean Danischevsky | Compositor |
| Pete Jopling | Compositor |
| Fred Place | Compositor |
| Jim Steel | Compositor |
| Niki Wakefield | Compositor |
| John Kilshaw | 3D Artist |
| Gaël Seydoux | 3D Artist |
| Laurent-Paul Robert | 3D Artist |
| Gia Sadwhani | 3D Artist |
| Vanessa Gratton | 3D Artist |
| Adam Inglis | Digital Intermediate Colorist |
| Andy Godden | Title Designer |
| Jonathan Fawkner | Visual Effects Supervisor |
| Frazer Churchill | Visual Effects Supervisor |
| Jamie Shemeld | Online Editor |
| Patrick Grillo | Production Accountant |
| Lasfer Abdelghni | Stunts |
| Richard Bradshaw | Stunts |
| Serge Crozon-Cazin | Stunts |
| Jim Dowdall | Stunts |
| Abdou Elyounsi | Stunts |
| Dave Fisher | Stunts |
| Youssef Ibaoui | Stunts |
| Charles Jarman | Stunts |
| Jean-François Lenogue | Stunts |
| Tony Lucken | Stunts |
| Daniel Naprous | Stunts |
| Efosa Otuomagie | Stunts |
| Cedric Proust | Stunts |
| Faycal Attougui | Stunts |
| Stuart Clark | Stunts |
| Clive Curtis | Stunts |
| Eric Etje | Stunts |
| Paul Howell | Stunts |
| Othman Ilyassa | Stunts |
| Morgan Johnson | Stunts |
| Philippe Losson | Stunts |
| Abderrazak El Moustaghit | Stunts |
| Gerard Naprous | Stunts |
| Heather Phillips | Stunts |
| Nabil Reda | Stunts |
| Bill Weston | Stunts |
| Ahmed Boubker | Stunts |
| Gaëlle Cohen | Stunts |
| Ray De-Haan | Stunts |
| Jamie Edgell | Stunts |
| Neil Finnighan | Stunts |
| Gaston Morrison | Stunts |
| Ernie Jackson | Stunts |
| Derek Lea | Stunts |
| Trevor Lovell | Stunts |
| Mark Anthony Newman | Stunts |
| Louis-Marie Nyee | Stunts |
| Dominic Preece | Stunts |
| Florian Robin | Stunts |
